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A number of posts about 'whether 2XCPETs are an objective indicator of PEM' and 'the definition of PEM' have been moved to Post-Exertional Malaise - a discussion including defining and measuring PEM

Gosh. In my non-exercise physiologist way, I'll give you a personal example to try to explain what I am saying. I participated in a two day CPET. I did the first CPET in the early afternoon. Later that night, I had a period of PEM for some hours - crushing pain, feeling ill, chills, glands...

Heading off topic, but just because Workwell say something, doesn't necessarily make it true. The 2xCPET does seem to show an abnormal reaction to exercise in ME/CFS. A reduced workrate at Anaerobic Threshold on the second test isn't what I and most people call PEM though. That reduced...

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5743676/ Abstract Musculoskeletal pain due to ischemia is present in a variety of clinical conditions including peripheral vascular disease (PVD), sickle cell disease (SCD), complex regional pain syndrome (CRPS), and even fibromyalgia (FM). The...

So interesting @SNT Gatchaman.

Looks to have been well done. A number of familiar names there :thumbup:

https://www.phcc.org.nz/briefing/long-covid-aotearoa-nz-risk-assessment-and-preventive-action-urgently-needed On the Public Health Communication Centre Aotearoa Amanda Kvalsvig, Anna E. S. Brooks, John D. Potter, Mona Jeffreys, Julie Bennett, David Davies-Payne, Jonathan Kennedy, Dianne...

There was an interview with epidemiologist Michael Baker on First Up on Radio NZ this morning. Michael Baker has been a reliably good commentator throughout the pandemic. He and a number of others have authored an article on the impact of Long Covid that will be available today - it sounds to...

I see from SNT's bolding that he has also noted the fact that this author, even after going through this awful process of having significant pain dismissed as a psychological reaction, and even after being motivated enough to write up her experience in a paper and reflecting on the issue, still...

I think it's worth acknowledging the particular issues many of us face that can make decision-making more difficult, regardless of any intrinsic specific executive dysfunction. It can be hard to know how we will be functioning in the future, and so we may feel rather ambivalent about committing...

X thread continues: Thanks EMEC.

I'll resist the temptation to find an appropriate gif, but, :thumbup:

(Perth, Australia) Investigation of motoneurone firing behaviour and associations with symptom severity in ME/CFS. Interesting sounding research project looking for participants in Perth, Western Australia

Fereshteh Jahanbani1*, Justin C. Sing2, Rajan D. Maynard1, Shaghayegh Jahanbani3, Janet Dafoe4, Whitney Dafoe4, Nathan Jones1, Kelvin J. Wallace1, Azuravesta Rastan1, Hannes Rost2, Holden Maecker5, Michael P. Snyder6, Ronald W. Davis4 Presumably Whitney Dafoe is the patient. A few red flags...

While trying to understand poetinsf's post, I briefly contemplated @Andy in fluffy pyjamas...

Cognitive tests Spinal fluid Neuroimaging some overlap but interesting underwhelming result, given these three regions were the most different out of 39 regions.

Fukuda criteria

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5393352/ Abstract The purpose of this study was to investigate whether CFS patients without comorbid psychiatric diagnoses differ from CFS patients with comorbid psychiatric diagnoses and healthy control subjects in neuropsychological performance...

There's a brief mention in this post. NICE Guideline review: Call for evidence on myalgic encephalomyelitis (or encephalopathy)/chronic fatigue syndrome, deadline 16th Oct 2019 The study pre-dates the establishment of this forum. For studies from 2017 or before that aren't here, threads on the...