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  1. Sean

    EAPM 2025 (European Association Of Psychosomatic Medicine)

    What most strikes me about the BPS movement is its lack of humility. They are utterly certain they are correct, and are instead entirely focused on how to market it to the lay public, the profession, and the political class.
  2. Sean

    Open Research study on ME/CFS and rest

    Convalescence is a concept and term that could be useful for us. Good chance, I think, that a lot more patients would do considerably better in the long term, even if not actually fully recovering, if they were both diagnosed early, and allowed to convalesce adequately in the early stages.
  3. Sean

    News from the USA, United States of America

    It is staring the medical profession and governments right in the face, and yet... *crickets*
  4. Sean

    SequenceME genetic study - from Oxford Nanopore Technologies, the University of Edinburgh and Action for ME

    It's pathetic, isn't it. They will not commit to the one thing that will help both us and their short-sighted budgetary obsessions, which is a solid basic research program. How many decades have been lost now because of this and the blocking of non-psych research by the psychs?
  5. Sean

    General thread on functional disorders in Denmark

    Damning with faint praise, indeed.
  6. Sean

    Loss of CRH neurons and other neural changes in ME/CFS autopsy study - University of Amsterdam

    For a start, the unremarkable fact of the additional burdens of normal ageing on top of serious chronic and very badly managed disease need to be factored in. If you are already barely functional it does not take much extra burden to crash the whole show. Indeed. The lack of decent...
  7. Sean

    Interventions that manipulate how patients report symptoms as a separate form of bias

    I remain deeply and increasingly skeptical of the whole CBT show.
  8. Sean

    Indistinguishable mitochondrial phenotypes after exposure of healthy myoblasts to myalgic encephalomyelitis or control serum, 2026, Ryback et al

    As disappointing as any negative result is for a previously promising preliminary finding, nonetheless it is far better to know it is not holding up so efforts and funding can be better allocated to other possibilities. Onward ho!
  9. Sean

    Invisible Illness A History, from Hysteria to Long Covid, 2026, Mendenhall (book)

    Yep. Why is he so special and important that he gets such endless uncritical deference and protection? How such a person has been allowed to become so powerful and beyond accountability, indeed lavishly rewarded for his failure and misbehaviour, speaks disturbing volumes about the broader...
  10. Sean

    Multicentre validation of a patient-reported outcome measure for functional movement disorders 2026 Michaelis et al

    Still not seeing the demonstration of content validity. Just more proof of rampant confirmation bias. Same as it ever was.
  11. Sean

    Scottish ME/CFS clinical service provision

    “It’s at a level of the brain you are not in control of” - understanding this is essential for recovery. 'You have no control over it, and here is how to take control over it.' :cautious:
  12. Sean

    2025-2026 Norwegian chronic fatigue guidelines - draft published

    Ah. Thanks. Usual trick, bury it deep and misrepresent the problem and solution anyway. These arseholes really think we are foolish flakes who just need to taken by a firm guiding hand and treated like moronic wayward 5 year olds. Indeed, but worse. I regard this stuff now as straight fraud...
  13. Sean

    2025-2026 Norwegian chronic fatigue guidelines - draft published

    exercise-induced exacerbations (PEM) It is not exercise induced, it is effort induced. These are fundamentally different. The distinction matters because some want to keep the focus on physical exercise and hence the understanding limited to deconditioning type interpretations, not on the...
  14. Sean

    Instruments for measuring fatigue in people with rheumatic and musculoskeletal diseases: a systematic review of measurement properties 2025 Machado+

    I am becoming actively hostile to questionnaires, and now operate on the presumption they are of very limited and uncertain value at best, and typically worse than that. Problematic enough a tool in the hands of honest and diligent researchers with the most honourable intentions, and an open...
  15. Sean

    Instruments for measuring fatigue in people with rheumatic and musculoskeletal diseases: a systematic review of measurement properties 2025 Machado+

    "Fatigue is described as being overwhelming, distressing, extreme, not restored by sleep, multidimensional and part of a vicious circle where fatigue feeds and fosters itself.11–13" Ref 12 being Sharpe M. Cognitive behavior therapy for chronic fatigue syndrome: efficacy and implications. Am J...
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