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  1. Samuel

    Neurologic sequalae of COVID-19 are determined by immunologic imprinting from previous Coronaviruses, 2022, Marianna Spatola et al

    perhaps hard to find good data, but do pwme have lots of colds in childhood? could that be relevant? or [prhaps less relevnt to this study] long-lasting ones?
  2. Samuel

    Circadian rhythm disruption in [ME/CFS]: Implications for the post-acute sequelae of COVID-19, 2022, McCarthy

    [i am posting old posts in my n>2000 firefox tabs. at current state idk if this or others make sense but i do not want to discard all of them.] "we" in your description struck me as potentially significant here. idk if this kind of thing is typically recognized as a clue. the 2 of you might...
  3. Samuel

    Studying severe long COVID to understand post-infectious disorders beyond COVID-19, 2022, Brodin, COVID Human Genetic Effort Consortium et al

    > they state that they wish to exclude pw psychosomatic complaints, implying they consider psychosomatic complaints to be a real thing. perhaps this bothers me more than it should but it does. if you are going to use that word in any legitimizing context, then you need to define what you do...
  4. Samuel

    Inflammation-type dysbiosis of the oral microbiome associates with the duration of COVID-19 symptoms and long-COVID, 2021, Haran et al

    i have encountered research that says that inflammation [edit: inflammatory cytokines] can be the cause of dental problems. do pwme have more than normal, after controlling for diet, dental hygiene practices, or anything else?
  5. Samuel

    Bayesian statistics improves biological interpretability of metabolomics data from human cohorts, 2023, Brydges, Che, Lipkin and Fiehn

    maybe the answer can be found at https://www.sciencedirect.com/topics/mathematics/bayes-rule ? disclaimer: i am completely incapable of anything.
  6. Samuel

    ‘Kind of Awkward’: Doctors Find Themselves on a First-Name Basis, NYT

    i think the medical industry needs to focus less on authority over the customer and more on medicine. i'd like to see an arrogance-ectomy of the entire industry. honorifics are ok if yours is used also.
  7. Samuel

    Covid-19 vaccines and vaccinations

    could the newer-variant-including bivalents work better in those who have not gotten vaccinated yet? has that been studied? i refer to the immune system fighting the last war phenomenon.
  8. Samuel

    Addiction drug shows promise lifting long COVID brain fog, fatigue

    I tried low-dose naltrexone (LDN) for m.e. for a month, but had constant nausea and several episodes of prolonged severe nausea, vomiting, delayed gastric emptying, sweating, diarrhea, and worse IBS. In one episode, I needed to vomit for about 7 hours but could not. Strange regurgitating...
  9. Samuel

    Covid-19 vaccines and vaccinations

    Merged thread Preventing vaccine reactions here is a very short youtube from klimas that for health reasons i cannot watch but looks like it could be useful. i think the talk is new and not her earlier written advice. this thread is for discussion, science, treatment, who is at risk...
  10. Samuel

    A Double-Blind, Placebo-Controlled, Randomized, Clinical Trial of the TLR-3 Agonist Rintatolimod in Severe Cases of CFS, Strayer et al, 2012

    > What I am saying is that for someone more severe that could be the difference between an essential task making you permanently worse or being recoverable from at 14%. And that being able to live more weeks without such 'heavy PEM' knocking someone downwards could indeed stop that inherent...
  11. Samuel

    Covid-19 vaccines and vaccinations

    Merged thread Moderna COVID-19 Booster Likely Triggers Acquired Angioedema https://angioedemanews.com/news/covid-19-booster-vaccine-trigger-of-acquired-angioedema/ === p.s. i have angioedema, with usual angioedema features, triggered by extremely small amounts of a specific, very common...
  12. Samuel

    The Atlantic - Long COVID Has Forced a Reckoning for One of Medicine's Most Neglected Diseases - by Ed Yong

    > but that would take massive lobbying and political action that is one reason i like the growing alliance.
  13. Samuel

    Circadian skin temperature rhythm and dysautonomia in [ME/CFS]: ... endothelin-1 in vascular dysregulation, 2023, Cambras et al

    Post with a link to the final paper here ******** Source: Research Square Preprint Date: September 21, 2022 URL: https://www.researchsquare.com/article/rs-2044838/v1 Circadian skin temperature rhythm and dysautonomia in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: the role...
  14. Samuel

    Ever-changing but always constant: “Waves” of disability discrimination during the COVID-19 pandemic in the United States, 2022, Lund and Ayers

    thank you for posting this. elsevier, in its infinite wisdom, however, has denied my humanity with a captcha that just decides i am not after i correctly answer their qs. === well i am denied access to vaccines, although nobody in the solar system would seem to agree. i cannot leave the...
  15. Samuel

    What items/documents would you like to send to GPs/primary care physicians if you were doing a mail-out?

    i have the problem trying to even scan part of this thread that i do with my notes from many years of saving links. with my sevre/extree executive dysfunction i cannot possibly organize them or figure out which to send. on top of that i can't read them to vet them. if i could, then i could...
  16. Samuel

    Nature - Online harassment: a toolkit for protecting yourself from abuse

    when do we get the big expose in major media about the development of the harassmenet narrative and about the smc. is such an expose not possible or counterproductive?
  17. Samuel

    Long Covid in the media and social media 2022

    cannot read more than part o it or health reasons but yong seems to understand not only scientific and other facts, and teh central topics, but also the kind of rhetoric that is needed to get past the persecution and stupidity. in this case he slides the persecuted diseases in sideways while...
  18. Samuel

    Open 2022 Pilot study in Norway - Daratumumab in ME/CFS

    > moderate to severe ME patients > Participants need to be able to travel to i think it is worth making very clear to newcomers and all that many definitions of severe make that a contradiction.
  19. Samuel

    UK Clock Club

    a critical field. with at least one unwanted member. i have permanent jetlag. reversed phase. i am still waking up [takes all day, most days never fully wake up and go to bed again nbefore i can do anything useufl] from going to bed when it was light out. residents of bangalore, i see on...
  20. Samuel

    Genetic Risk Factors for ME/CFS Identified using Combinatorial Analysis, 2022, Das et al

    is this statistically sound? multiple comparisons or so? what is combinatorial analysis? is there an explosion and what is done to reduce it? apologies for asking a q that cold be looked up.
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