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  1. J

    Tomorrow ONLY - 6x match for your donation on Facebook—OMF

    #TripleTuesdayOMF - Giving Tuesday Special Facebook Matching Gift We’d like to highlight a unique opportunity to have your donation to OMF 6x matched on International Giving Tuesday, starting tomorrow (Tuesday, December 3) at 5 AM Pacific / 8 AM Eastern / 1 PM London. When you donate to our...
  2. J

    Immunostimulatory gut bacteria, Science

    Popular article https://www.google.com/amp/s/www.mskcc.org/blog/milking-it-study-mice-suggests-lactose-diet-feeds-dangerous-gut-bacteria%3famp
  3. J

    Immunostimulatory gut bacteria, Science

    perspective https://science.sciencemag.org/content/366/6469/1077 Article https://science.sciencemag.org/content/366/6469/1143 Or https://science.sciencemag.org/content/366/6469/1143.editor-summary
  4. J

    Do Medical Journals Publish Original Work Anymore? Enough already with meta-analyses

    https://www.medpagetoday.com/blogs/revolutionandrevelation/75045 Amen
  5. J

    Americans dying young at alarming rates, Washington Post

    @Wonko please blame Jeff Bezos as he owns it.
  6. J

    Americans dying young at alarming rates, Washington Post

    https://www.washingtonpost.com/health/theres-something-terribly-wrong-americans-are-dying-young-at-alarming-rates/2019/11/25/d88b28ec-0d6a-11ea-8397-a955cd542d00_story.html
  7. J

    A proposal for ME Action: a commitment to evidence-based medicine

    The knee arthritis mention was absolutely not meant to be a personal call out— it was random. Maybe I should have said knee osteoarthritis— apologies if my words were misconstrued. Well one difference between MECFS and other bad ones is that I can watch an hour of news on TV (I live in the US)...
  8. J

    A proposal for ME Action: a commitment to evidence-based medicine

    I agree with @debored13 here. I disagree with the approach of this exercise’s “cautionary principle”. Cautionary Principle might be OK for knee arthritis, but not good for a serious disease where you get worse over time. I believe aggressive approaches to treatment— with informed consent—are...
  9. J

    Livestream: Ron Davis to speak at Columbia University

    Suramin worked (graph on right)
  10. J

    Livestream: Ron Davis to speak at Columbia University

    Yup, IMO that’s why these people who spend all their time on twitter saying that they have the only “true disease” because they were infected by Enterovirus XYZ sub-strain 321 are not helping anyone, including themselves.
  11. J

    Livestream: Ron Davis to speak at Columbia University

    Yeah not so positive.... at one point he said something about focusing on prevention rather than treatment....
  12. J

    Identification of actin network proteins, talin-1 and filamin-A, in circulating extracellular vesicles as blood biomarkers...ME/CFS 2019, Eguchi et al

    This is the “something in the blood” @Simon M ETA: changed "what's" to "something"
  13. J

    Identification of actin network proteins, talin-1 and filamin-A, in circulating extracellular vesicles as blood biomarkers...ME/CFS 2019, Eguchi et al

    Wow... probably a pretty significant paper... identified what’s in the EV’s.
  14. J

    Livestream: Ron Davis to speak at Columbia University

    So this is at Albert Einstein COM not Columbia http://www.einstein.yu.edu/departments/genetics/calendar/?cMonth=8&cYear=2241 (only of interest because I could attend IRL)
  15. J

    Livestream: Ron Davis to speak at Columbia University

    Wait....Albert Einstein COM is not part of Columbia.... wonder where this is https://en.m.wikipedia.org/wiki/Albert_Einstein_College_of_Medicine
  16. J

    Cyclophosphamide

    Lactobionic Acid Conjugated Quercetin Loaded Organically Modified Silica Nanoparticles Mitigates Cyclophosphamide Induced Hepatocytotoxicity https://www.dovepress.com/lactobionic-acid-conjugated-quercetin-loaded-organically-modified-sili-peer-reviewed-article-IJN
  17. J

    Alzheimer's Trial: Lessons From a Failed Drug — What the pragmatic trial of minocycline can teach us

    https://www.medpagetoday.com/neurology/alzheimersdisease/83410 mentions microglia inflammation. Cheap trial *only* cost $2 million.
  18. J

    Inhibition of Upf2-Dependent Nonsense-Mediated Decay Leads to Behavioral and Neurophysiological Abnormalities by Activating the Immune Response

    They also used minocycline successfully on the mice.
  19. J

    Inhibition of Upf2-Dependent Nonsense-Mediated Decay Leads to Behavioral and Neurophysiological Abnormalities by Activating the Immune Response

    Also highlighted here in Science Translational Medicine “A no-nonsense treatment for autism spectrum disorder” https://stm.sciencemag.org/content/11/516/eaaz3723
  20. J

    Inhibition of Upf2-Dependent Nonsense-Mediated Decay Leads to Behavioral and Neurophysiological Abnormalities by Activating the Immune Response

    https://www.cell.com/neuron/pdfExtended/S0896-6273(19)30733-0 Used cyclophosphamide to treat autism symptoms in mice by reducing brain inflammation.
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