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  1. forestglip

    Preprint A Proposed Mechanism for ME/CFS Invoking Macrophage Fc-gamma-RI and Interferon Gamma, 2025, Edwards, Cambridge and Cliff

    Using a percentile here somewhat downplays it. On the Qeios page for these stats, it says this paper is ranked number 1 out of 8 for papers of a similar age from Qeios.
  2. forestglip

    The Scientist: 'The “Virus Hunter” Who Advanced Public Health, One Tool at a Time' [Ian Lipkin]

    The Scientist: 'The “Virus Hunter” Who Advanced Public Health, One Tool at a Time' In his 40-year epidemiology career, Ian Lipkin has done it all: from discovering 2,000 viruses to solving a nationwide SARS crisis. by Shelby Bradford, PhD ---- 'Alongside his pathogen discovery work at the turn...
  3. forestglip

    Chronically Ignored - Investigative Documentary

    The Canary: 'A groundbreaking documentary on ME/CFS is now available to international audiences' ---- 'The documentary has gone live to rent on Vimeo. The film is in German, but international viewers can select various subtitle options to follow it in their preferred language. However, if you...
  4. forestglip

    Long-COVID is associated with increased absenteeism from work, 2025, Kim et al

    Long-COVID is associated with increased absenteeism from work Jaewhan Kim, Sanghoon Lee, Peter Weir [Line breaks added] Abstract Long-COVID, defined as COVID-19 symptoms persisting for more than 3 months, may lead to persistent health issues requiring extensive medical care. Despite its...
  5. forestglip

    Genetics of monozygotic twins reveals the impact of environmental sensitivity on psychiatric and neurodevelopmental phenotypes, 2025, Assary et al

    I tried reading the paper, and can't understand most of it. But I think the main idea is this: they're not looking for SNPs that cause these conditions. They're looking for SNPs that cause increased variation in getting the condition (in other words, SNPs that increase the influence of...
  6. forestglip

    Genetics of monozygotic twins reveals the impact of environmental sensitivity on psychiatric and neurodevelopmental phenotypes, 2025, Assary et al

    Genetics of monozygotic twins reveals the impact of environmental sensitivity on psychiatric and neurodevelopmental phenotypes Abstract Individual sensitivity to environmental exposures may be genetically influenced. This genotype-by-environment interplay implies differences in phenotypic...
  7. forestglip

    Amplification of select autonomous HERV loci and surrounding host gene transcription in monocytes from patients with [PASC], 2025, Koo et al

    Amplification of select autonomous HERV loci and surrounding host gene transcription in monocytes from patients with post-acute sequelae of COVID-19 Hyunmin Koo, Casey D. Morrow [Line breaks added] Background The human genome contains approximately 3,200 near full-length autonomous human...
  8. forestglip

    The Implications and Predictability of Sleep Reversal for People with [ME/CFS]: A Machine Learning Approach, 2025, Dietrich, Jason et al

    The Implications and Predictability of Sleep Reversal for People with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Machine Learning Approach Meghan P. Dietrich, Raam Pravin, Jacob Furst, Leonard A. Jason Background/Objectives: Impaired sleep is one of the core symptoms of myalgic...
  9. forestglip

    Very severe French patient needs help

    I can't find one from a quick search, but maybe an auto-translation of the relevant parts would be okay?
  10. forestglip

    Forensic biomarker discovery: Utilising metabolomics to elucidate prospective fatigue biomarkers for eventual roadside detection, 2025, Hamilton et al

    Interestingly, scyllo-inositol has been tested as a treatment for Alzheimer's, bipolar disorder, and down syndrome, with apparently negative results in all. (Wikipedia)
  11. forestglip

    Forensic biomarker discovery: Utilising metabolomics to elucidate prospective fatigue biomarkers for eventual roadside detection, 2025, Hamilton et al

    Forensic biomarker discovery: Utilising metabolomics to elucidate prospective fatigue biomarkers for eventual roadside detection Aaron Hamilton, Luke Whiley, Maria Kadyrov, Brendan Chapman Highlights • Metabolomics can be used to identify biomarkers for fatigue. • Scyllo-inositol...
  12. forestglip

    Preprint Indistinguishable mitochondrial phenotypes after exposure of healthy myoblasts to myalgic encephalomyelitis or control serum, 2025, Ryback et al

    Agree with other posters - very well written and thorough. I wonder if the diagnostic criteria might be a factor. CCC in Fluge et al, but CCC and/or IOM here, so maybe the factor in the blood wasn't necessarily related to ME/CFS, but was related to a comorbidity required by CCC but not by IOM.
  13. forestglip

    Deep Sequencing of BCR Heavy Chain Repertoires in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, 2025, Ryback et al

    Here's an association, but this specifically is only describing healthy controls. It's a positive correlation between Vitality (SF-36) and IGHV3-23/IGHV3-30. r=0.527, q=0.039. The more they have the healthier they are, so opposite direction of the association between controls and ME/CFS in the...
  14. forestglip

    Webinar 2pm today (Friday 6 June 2025): Genetics Centre of Excellence (Edinburgh Ponting lab): update on recent research

    Wow I just put together that chillier is the one of the people from your 'something in the blood' post. The username makes sense now, I thought they were just cold. Someone asked if she falsified the nanoneedle study. She said it's hard to compare her result to Ron Davis's, but that Fatima...
  15. forestglip

    Nature: "Science-integrity project will root out bad medical papers ‘and tell everyone’"

    Nature: "Science-integrity project will root out bad medical papers ‘and tell everyone’" ---- 'The Center for Scientific Integrity — the non-profit organization that runs Retraction Watch — has launched a project aimed at rounding up flawed and fake medical-research papers and neutralizing...
  16. forestglip

    Pathogen-specific exposure is associated with multisite chronic pain: A prospective cohort study, 2025, Fang et al

    Pathogen-specific exposure is associated with multisite chronic pain: A prospective cohort study Jialiu Fang, Zemene Demelash Kifle, Jing Tian, Silvana Bettiol, Flavia Cicuttini, Graeme Jones, Feng Pan [Line breaks added] Abstract Evidence suggests that pathogens may influence pain perception...
  17. forestglip

    Deoxygenation Trends and Their Multivariate Association with Self-Reported Fatigue in Post-COVID Syndrome, 2025, Ladek et al

    Deoxygenation Trends and Their Multivariate Association with Self-Reported Fatigue in Post-COVID Syndrome Anja-Maria Ladek, Marianna Lucio, Andreas Weiß, Thomas Knauer, Helena Sarmiento, Miriam Ilgner, Marie Jakobi, Laura Barteczko, Marion Ganslmayer, Jürgen Rech, Antonio Bergua, Christian Y...
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