autoantibodies

  1. Sly Saint

    Observational Study of Repeat Immunoadsorption in Post-COVID ME/CFS Patients with Elevated Beta-2-Adrenergic Receptor Autoantibodies,2023, Stein et al

    Scheibenbogen et al Abstract There is increasing evidence for an autoimmune aetiology in post-infectious Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). SARS-CoV-2 has now become the main trigger for ME/CFS. We have already conducted two small proof-of-concept studies of IgG...
  2. SNT Gatchaman

    Generation of potentially inhibitory autoantibodies to ADAMTS13 in coronavirus disease 2019, 2023, Doevelaar et al.

    Generation of potentially inhibitory autoantibodies to ADAMTS13 in coronavirus disease 2019 Doevelaar, Adrian A. N.; Bachmann, Martin; Hölzer, Bodo; Seibert, Felix S.; Rohn, Benjamin J.; Zgoura, Panagiota; Witzke, Oliver; Dittmer, Ulf; Brenner, Thorsten; Paniskaki, Krystallenia; Yilmaz, Serap...
  3. M

    Protocol A Proof-of-concept Study to Evaluate the Efficacy and Safety of Rozanolixizumab to Treat [Adults] With Severe Fibromyalgia Syndrome, 2022-4, UK

    https://classic.clinicaltrials.gov/ct2/show/NCT05643794?recrs=abdf&type=Intr&cond=Fibromyalgia&draw=3&rank=11 Someone is moving ahead with the theory of autoimmune antibodies for fibromyalgia
  4. Arnie Pye

    Preprint Autoantibodies to Selenoprotein P in Patients with CFS suggest Selenium Transport Impairment and .. Resistance to Thyroid Hormone, 2023, Qian Sun et a

    Preprint, not peer reviewed : https://papers.ssrn.com/sol3/papers.cfm?abstract_id=4332223 Autoantibodies to Selenoprotein P in Patients with Chronic Fatigue Syndrome suggest Selenium Transport Impairment and Acquired Resistance to Thyroid Hormone Qian Sun1,2,†, Elisa Oltra3,†, D. A. Janneke...
  5. Wyva

    Clinical improvement of Long-COVID is associated with reduction in autoantibodies, lipids, and inflammation following (...), 2023, Achleitner et al

    Full title: Clinical improvement of Long-COVID is associated with reduction in autoantibodies, lipids, and inflammation following therapeutic apheresis Abstract In the aftermath of the COVID-19 pandemic, we are witnessing an unprecedented wave of post-infectious complications. Most...
  6. Hutan

    Autoantibodies against muscarinic cholinergic receptor in chronic fatigue syndrome, 2003, Tanaka et al

    An old study that has been included in a list of studies finding issues with G protein-coupled receptors. https://pubmed.ncbi.nlm.nih.gov/12851722/. Paywall Abstract The disturbance of the central nervous system and immunological abnormalities have been suggested in patients with chronic...
  7. J

    Autoantibodies against chemokines post-SARS-CoV-2 infection correlate with disease course, 2023, Cavalli et al

    Abstract Infection with severe acute respiratory syndrome coronavirus 2 associates with diverse symptoms, which can persist for months. While antiviral antibodies are protective, those targeting interferons and other immune factors are associated with adverse coronavirus disease 2019 (COVID-19)...
  8. MSEsperanza

    Immune adsorption for the treatment of fatigue-dominant long-/post-COVID syndrome—a case series [...], 2023, Ruhe et al

    Immune adsorption for the treatment of fatigue-dominant long-/post-COVID syndrome—a case series of standardized individual experimental therapy Research letter / case series of 10 patients. Announced English version not published yet. So in lieu of an abstract here's a google translate link...
  9. Hutan

    Anti-ganglionic acetylcholine receptor antibodies in functional neurological symptom disorder/conversion disorder, 2023, Nagata et al

    https://www.frontiersin.org/articles/10.3389/fneur.2023.1137958/full Open access Team from Kagoshima, Japan Objective: Autoimmune autonomic ganglionopathy (AAG) is a rare disorder characterized by autonomic failure associated with the presence of anti-ganglionic acetylcholine receptor (gAChR)...
  10. SNT Gatchaman

    Autoantigen profiling reveals a shared post-COVID signature in fully recovered and Long COVID patients, 2023

    Autoantigen profiling reveals a shared post-COVID signature in fully recovered and Long COVID patients Multiple authors from UCSF Some individuals do not return to baseline health following SARS-CoV-2 infection, leading to a condition known as Long COVID. The underlying pathophysiology of Long...
  11. SNT Gatchaman

    Severe COVID-19 induces autoantibodies against angiotensin II that correlate with blood pressure dysregulation and disease severity, 2022, Briquez &

    Severe COVID-19 induces autoantibodies against angiotensin II that correlate with blood pressure dysregulation and disease severity Briquez PS, Rouhani SJ, Yu J, Pyzer AR, Trujillo J, Dugan HL, Stamper CT, Changrob S, Sperling AI, Wilson PC, Gajewski TF, Hubbell JA, Swartz MA Patients infected...
  12. Sly Saint

    Dysregulated autoantibodies targeting vaso- and immunoregulatory receptors in Post COVID Syndrome correlate with symptom severity 2022 Scheibenbogen

    Most patients with Post COVID Syndrome (PCS) present with a plethora of symptoms without clear evidence of organ dysfunction. A subset of them fulfills diagnostic criteria of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). Symptom severity of ME/CFS correlates with natural...
  13. Wyva

    Circulating anti-nuclear autoantibodies in COVID-19 survivors predict long-COVID symptoms, 2022, Mukherjee et al

    Abstract Background Autoimmunity has been reported in patients with severe COVID-19. We investigated whether antinuclear/extractable-nuclear antibodies (ANAs) were present up to a year after infection, and if they were associated with the development of clinically relevant Post-Acute Sequalae...
  14. Andy

    Anti-neuronal antibodies against brainstem antigens are associated with COVID-19, 2022, Lucchese et al

    Summary Background Understanding how SARS-CoV-2 affects respiratory centres in the brainstem may help to preclude assisted ventilation for patients in intensive care setting. Viral invasion appears unlikely, although autoimmunity has been implicated, the responsible antigens remain unknown. We...
  15. Hutan

    Antibodies to β adrenergic and muscarinic cholinergic receptors in patients with CFS, 2016, Loebel et al

    https://www.sciencedirect.com/science/article/pii/S0889159115300209?via%3Dihub Open Access Madlen Loebel 1, Patricia Grabowski 2, Harald Heidecke 3, Sandra Bauer 2, Leif G Hanitsch 2, Kirsten Wittke 2, Christian Meisel 4, Petra Reinke 5, Hans-Dieter Volk 6, Øystein Fluge 7, Olav Mella 8, Carmen...
  16. M

    Detection of G Protein-Coupled Receptor Autoantibodies in Postural Orthostatic Tachycardia Syndrome Using Standard Methodology (2022) Hall et al

    Detection of G Protein-Coupled Receptor Autoantibodies in Postural Orthostatic Tachycardia Syndrome Using Standard Methodology (the title is a bit misleading, read the whole abstract) Main author is Dr Satish Raj from Calgary. Abstract Background: Postural orthostatic tachycardia syndrome...
  17. Ryan31337

    Platelet Storage Pool Deficiency and Elevated Inflammatory Biomarkers Are Prevalent in POTS, 2022, Gunning, Grubb et al

    Platelet Storage Pool Deficiency and Elevated Inflammatory Biomarkers Are Prevalent in Postural Orthostatic Tachycardia Syndrome by William T. Gunning, Paula M. Kramer, Jacob A. Cichock, Beverly L. Karabin, Sadik A. Khuder, Blair P. Grubb doi.org/10.3390/cells11050774...
  18. Andy

    Transcutaneous vagus nerve stimulation attenuates autoantibody-mediated cardiovagal dysfunction & inflammation in a rabbit model of [POTS], 2022, Deng

    Abstract Purpose Previous studies demonstrated M2 muscarinic acetylcholine receptor-activating autoantibodies (M2R-AAb) were present in some patients with postural tachycardia syndrome (POTS). This study examines how these autoantibodies might contribute to the pathophysiology of POTS, and...
  19. Wyva

    Multiple Early Factors Anticipate Post-Acute COVID-19 Sequelae, 2022, Su et al

    Highlights Longitudinal multiomics associate PASC with autoantibodies, viremia and comorbidities Reactivation of latent viruses during initial infection may contribute to PASC Subclinical autoantibodies negatively correlate with anti-SARS-CoV-2 antibodies Gastrointestinal PASC uniquely present...
  20. Samuel

    Early diagnostics of autoinflammatory disorders associated with post-viral CFS and cognitive impairments in chronic ... herpes, 2021, Nesterova et al

    vvv Source: Medical Immunology Vol 23, #4, pp 975-980 Date: July/August 2021 URL: https://www.mimmun.ru/mimmun/article/view/2439 https://www.mimmun.ru/mimmun/article/view/2439/1456 Early diagnostics of autoinflammatory disorders associated with post-viral chronic fatigue...
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