biomarker

  1. Sly Saint

    A nanoelectronics-blood-based diagnostic biomarker for ME/CFS (2019) Esfandyarpour, Davis et al

    By Open Medicine Foundation full article here: https://www.sanluisobispo.com/news/state/california/article229756099.html [have looked at the link but can't find the published paper?] eta: link now works this one takes you to where it's listed...
  2. W

    What is the normal value of the neutrophil-to-lymphocyte ratio? (2017) Forget, De Kock, et al.

    Background Neutrophil-to-lymphocyte ratio (NLR) has proven its prognostic value in cardiovascular diseases, infections, inflammatory diseases and in several types of cancers. However, no cut-off has been proposed on the basis of reference values coming from healthy population. Methods Routine...
  3. J

    Biological markers evaluated in randomized trials of psychological treatments for depression: a systematic review & meta-analysis (2019) Cristea et al

    I haven't looked at this, but it sounds interesting and relevant. It is accepted by the CBT-GET promoters that there are biological changes in patients with ME. A key part of their argument has always been that psychotherapy can bring about or reverse biological changes. Here is a study that...
  4. Andy

    Decreased Expression of the CD57 Molecule in T Lymphocytes of Patients with Chronic Fatigue Syndrome, 2019, Espinosa and Urra

    Paywalled at https://link.springer.com/article/10.1007/s12035-019-1549-7 alt https://sci-hub.se/https://link.springer.com/article/10.1007/s12035-019-1549-7
  5. Sly Saint

    Impact of Polypharmacy on Candidate Biomarker miRNomes for the Diagnosis of Fibromyalgia and ME/CFS:Striking Back on Treatments 2019 Oltra et al

    Impact of Polypharmacy on Candidate Biomarker miRNomes for the Diagnosis of Fibromyalgia and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Striking Back on Treatments Eloy Almenar-Pérez 1, Teresa Sánchez-Fito 1, Tamara Ovejero 2, Lubov Nathanson 3,4 and Elisa Oltra 2,5,* 1 Escuela de...
  6. MSEsperanza

    The European ME/CFS Biomarker Landscape project... (EUROMENE) (2016), Scheibenbogen et al

    Scheibenbogen et al (2016), The European ME/CFS Biomarker Landscape project: an initiative of the European network EUROMENE , Journal of Translational Medicine, https://translational-medicine.biomedcentral.com/articles/10.1186/s12967-017-1263-z#Sec4 pdf: The European ME/CFS Biomarker Landscape...
  7. Hutan

    Activin B is a novel biomarker for chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) diagnosis, 2017, Lidbury et al

    https://translational-medicine.biomedcentral.com/articles/10.1186/s12967-017-1161-4 Background Investigations of activin family proteins as serum biomarkers for chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME). CFS/ME is a disease with complex, wide-ranging symptoms, featuring...
  8. Andy

    Investigating causality in the association between vitamin D status and self-reported tiredness, 2019, Havdahl et al

    All of authors are from University of Bristol and include Crawley's mate, George Davey Smith. ME gets mentioned a number of times. Open access at https://www.nature.com/articles/s41598-019-39359-z Starting to build a narrative that our fatigue isn't anything out of the ordinary?
  9. Ravn

    Molecular Psychiatry (2019): Towards precision medicine for pain: diagnostic biomarkers and repurposed drugs

    An objective biomarker - gene expression patterns - for pain? Can this be true? https://www.nature.com/articles/s41380-018-0345-5 (A.B Niculescu et al.) Full text. The cohorts and the scientists are psychiatric patients/psychiatrists but otherwise the study seems to lean more biomedical - not...
  10. Andy

    miRNA profiling of circulating EVs in (ME/CFS), 2018, Almenar-Pérez et al

    Abstract only, or it's a poster presentation? https://search.proquest.com/openview/3ecbf2853f437616f4506cf68f104f30/1?pq-origsite=gscholar&cbl=2030046
  11. leokitten

    Serum neurofilament dynamics predicts neurodegeneration and clinical progression in presymptomatic Alzheimer’s disease (2019) Preische, et al.

    Might increased serum NfL also be a potential biomarker for ME/CFS since it is for Alzheimer’s and other neurological disorders? https://www.nature.com/articles/s41591-018-0304-3
  12. Webdog

    Possible Biomarker for Multiple Sclerosis Identified

    Possible Biomarker for Multiple Sclerosis Identified https://neurosciencenews.com/multiple-sclerosis-biomarker-10380/
  13. John Mac

    Prospective Biomarkers from Plasma Metabolomics of ME/CFS Implicate Redox Imbalance in Disease Symptomatology, 2018, Hanson et al

    https://www.mdpi.com/2218-1989/8/4/90
  14. Andy

    Low omega-3 index and polyunsaturated fatty acid status in patients with CFS/ME, 2018, Castro-Marerro et al

    Paywalled at https://www.plefa.com/article/S0952-3278(18)30053-X/fulltext
  15. Hoopoe

    Erythrocyte Deformability As a Potential Biomarker for Chronic Fatigue Syndrome, Davis et al (2018)

    www.bloodjournal.org/content/132/Suppl_1/4874 At the moment, the full article is not yet available. Edit: We have 3 threads on related or the same research by the same team: Erythrocyte Deformability As a Potential Biomarker for Chronic Fatigue Syndrome, Davis et al (2018) Altered Erythrocyte...
  16. Suffolkres

    Hand grip strength as a clinical biomarker for ME/CFS, 2018, Nacul et al

    Source: Frontiers in Neurology Preprint Date: November 5, 2018 URL: https://www.frontiersin.org/articles/10.3389/fneur.2018.00992/abstract Hand grip strength as a clinical biomarker for ME/CFS and disease severity ---------------------------------------------------------- Luis C. Nacul(*)...
  17. Mij

    Biomarker For Flu Susceptibility

    I've never had a flu jab my entire life (I'm 56), and don't feel that I've ever gotten the flu. Of course it's difficult to know for sure with M.E because I feel viral-like 80% of the time. Perhaps I get a milder form when exposed but not sure. Researchers at Stanford have discovered a way...
  18. Hip

    The buspirone challenge test clearly distinguishes ME/CFS patients from healthy controls: why is it not being developed and deployed?

    Moderator note: Link to @forestglip's excellent summary of what is known, as of August 2026, about the prolactin response to a buspirone challenge in ME/CFS here See also a Google document where some members are compiling findings and ideas related to prolactin response here. ******** I...
  19. Andy

    SMCI RAMSAY 2018: “Biomarkers of mitochondrial dysfunction and signaling in ME/CFS”, Blomberg and Rosen

    2018 Ramsay Award recipients https://solvecfs.org/ramsay-2018-meet-professor-jonas-blomberg-md-phd-dr-anders-rosen-md-phd/
  20. Webdog

    Scientific American: "We Need New Biomarkers for Alzheimer's Disease"

    Scientific American article on the search for an Alzheimer's biomarker, and how both the FDA and Bill Gates have made finding an inexpensive blood test for Alzheimer's a priority. We Need New Biomarkers for Alzheimer's Disease They're essential to coming up with better treatments, and a new...
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