Interventional Removal of Travelling Microthrombi Using Targeted Magnetic Microbubble
Yongjian Li; Zujie Gao; Xiaobing Zheng; Yunfan Pan; Jinlong Xu; Yan Li; Haosheng Chen
Microthrombus is one of the major causes of the sequelae of COVID-19 and leads to subsequent embolism and necrosis. Due to...
Differential Gene Expression in the Upper Respiratory Tract following Acute COVID-19 Infection in Ambulatory Patients That Develop Long COVID
Biondi, Mia J.; Addo, Mary; Zahoor, Muhammad Atif; Salvant, Elsa; Yip, Paul; Barber, Bethany; Smookler, David; Wasif, Sumaiyah; Gaete, Kayla; Kandel...
Tocilizumab Reduces Hypercoagulation in COVID-19 - Perspectives from The Coagulation and Immunomodulation Covid Assessment Coag-ImmCovA Clinical Trial.
Lou M Almskog; Anna Sjostrom; Jonas Sunden-Cullberg; Apostolos Taxiarchis; Anna Agren; Sara Freyland; Madeleine Borjesson; Agneta Wikman; Carl...
Reduction of hemagglutination induced by a SARS-CoV-2 spike protein fragment using an amyloid-binding benzothiazole amphiphile
Li, Meihan; Castro Lingl, Sascha; Yang, Jerry
COVID-19 infection is associated with a variety of vascular occlusive morbidities. However, a comprehensive understanding...
Fibrinaloid Microclots and Atrial Fibrillation
Kell, Douglas B.; Lip, Gregory Y. H.; Pretorius, Etheresia
Atrial fibrillation (AF) is a comorbidity of a variety of other chronic, inflammatory diseases for which fibrinaloid microclots are a known accompaniment (and in some cases, a cause, with a...
The Role of Heparin in Postural Orthostatic Tachycardia Syndrome and Other Post-Acute Sequelae of COVID-19
Gómez-Moyano, Elisabeth; Pavón-Morón, Javier; Rodríguez-Capitán, Jorge; Bardán-Rebollar, Daniel; Ramos-Carrera, Teresa; Villalobos-Sánchez, Aurora; Pérez de Pedro, Iván; Ruiz-García...
Now published: Cardiovascular symptoms of PASC are associated with trace-level cytokines that affect function of stem cell derived cardiomyocytes, 2024, Sinclair+']link here[/URL]
Preprint
Cardiovascular symptoms of PASC are associated with trace-level cytokines that affect the function of...
Rethinking coagulation: from enzymatic cascade and cell-based reactions to a convergent model involving innate immune activation
Yong, Jun; Toh, Cheng-Hock
Advancements in the conceptual thinking of hemostasis and thrombosis have been catalyzed by major developments within health research over...
Amyloid-Fibrinogen Aggregates Microclots Predict Risks of Disseminated Intravascular Coagulation and Mortality
Schofield, Jeremy; Abrams, Simon Timothy; Jenkins, Rosalind; Lane, Steven; Wang, Guozheng; Toh, Cheng-Hock
Microclots have been associated with various conditions, including post-acute...
Preprint
Blood-brain barrier disruption in Long COVID-associated cognitive impairment
Chris Greene, Ruairi Connolly, Declan Brennan, Aoife Laffan, Eoin O'Keeffe, Lilia Zaporojan, Emma Connolly, Cliona Ni Cheallaigh, Niall Conlon, Colin Doherty, Matthew Campbell
Vascular disruption has been...
A signature of platelet reactivity in CBC scattergrams reveals genetic predictors of thrombotic disease risk
Verdier, Hippolyte; Thomas, Patrick; Batista, Joana; Kempster, Carly; McKinney, Harriet; Gleadall, Nicholas; Danesh, John; Mumford, Andrew; Heemskerk, Johan W. M.; Ouwehand, Willem H...
Alterations to Sphingomyelin Metabolism Affect Hemostasis and Thrombosis
Jue Wang; Shiva Keshava; Kaushik Das; Richard Kolesnick; Xian-Cheng Jiang; Usha R. Pendurthi; L. Vijaya Mohan Rao
BACKGROUND: Our recent studies suggest that sphingomyelin levels in the plasma membrane influence TF (tissue...
Tale of two systems: the intertwining duality of fibrinolysis and lipoprotein metabolism
Wen Dai; Mark Castleberry; Ze Zheng
Fibrinolysis is an enzymatic process that breaks down fibrin clots, while dyslipidemia refers to abnormal levels of lipids and lipoproteins in the blood. Both...
Cerebrospinal Fluid Proteomic Profiles in Patients with Postherpetic Neuralgia
Kai Chen; Meng Wang; Dongju Long; Dingquan Zou; Xin Li; Ruixuan Wang; Yaping Wang; Lin Yang
The intrinsic mechanism of postherpetic neuralgia (PHN) remains unclear. Herein, we aimed to seek the hub proteins in the...
Integrated longitudinal multi-omics study identifies immune programs associated with COVID-19 severity and mortality in 1152 hospitalized participants
Jeremy P. Gygi; Cole Maguire; Ravi K. Patel; Pramod Shinde; Anna Konstorum; Casey P. Shannon; Leqi Xu; Annmarie Hoch; Naresh Jayavelu; IMPACC...
Longitudinal viscosity of blood plasma for rapid COVID-19 prognostics
Jennifer Illibauer; Tamara Clodi-Seitz; Alexander Zoufaly; Judith H Aberle; Wolfgang J Weninger; Manuela Foedinger; Kareem Elsayad
Blood Plasma Viscosity (PV) is an established biomarker for numerous diseases. While PV...
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