coagulation
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Sustained Vascular Inflammatory Effects of SARS-CoV-2 Spike Protein on Human Endothelial Cells, 2024, Gultom et al.
Sustained Vascular Inflammatory Effects of SARS-CoV-2 Spike Protein on Human Endothelial Cells Gultom, Mitra; Lin, Lin; Brandt, Camilla Blunk; Milusev, Anastasia; Despont, Alain; Shaw, Jane; Döring, Yvonne; Luo, Yonglun; Rieben, Robert Severe acute respiratory syndrome coronavirus 2...- SNT Gatchaman
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- coagulation complement endothelial cells endothelial dysfunction spike protein tnf vascular
- Replies: 0
- Forum: Long Covid research
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Preprint Proteomic and metabolomic profiling of plasma uncovers immune responses in patients with Long COVID-19, 2024, Wei et al
Proteomic and metabolomic profiling of plasma uncovers immune responses in patients with Long COVID-19 Yulin Wei, Hongyan Gu, Jun Ma, Xiaojuan Mao, Bing Wang, Weiyan Wu, Shimin Yu, Jinyuan Wang, Huan Zhao, yanbin he [Preprint] Abstract Long COVID is an often-debilitating condition with...- forestglip
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- arachidonic acid coagulation complement complement system glycerophospholipids gnai2 gpcr long covid platelets proteomics sphingolipids thrombospondin-1 transport tsp-1 tsp1
- Replies: 10
- Forum: Long Covid research
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Proteomic analysis of post-COVID condition: Insights from plasma and pellet blood fractions, 2024, Seco-González et al
Proteomic analysis of post-COVID condition: Insights from plasma and pellet blood fractions Alejandro Seco-González, Paula Antelo-Riveiro, Susana B. Bravo, P.F. Garrido, M.J. Domínguez-Santalla, E. Rodríguez-Ruiz, Á. Piñeiro, R. Garcia-Fandino Background Persistent symptoms extending beyond...- forestglip
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- antimicrobial peptides coagulation complement complement system cytoskeleton glycolysis immune system long covid oxidative stress proteomics
- Replies: 15
- Forum: Long Covid research
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Long-term dysregulation of plasma peptidome in mild and multiple COVID-19 recovered patients revealed by a novel peptidomics workflow, 2024, Song+
Long-term dysregulation of plasma peptidome in mild and multiple COVID-19 recovered patients revealed by a novel efficient peptidomics workflow Song, Zhijing; Liu, Chaoran; Liu, Yaozhou; Bian, Zheng; Sun, Qing; He, Ting; Su, Rong; Huang, Shengchun; Dai, Ningbin; Zhao, Ke li; Li, Yan; Liang, Kai...- SNT Gatchaman
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- coagulation complement immune lipids peptidomics
- Replies: 1
- Forum: Long Covid research
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Preprint Unraveling SARS-CoV-2 Host-Response Heterogeneity through Longitudinal Molecular Subtyping, 2024, Wang, Iwasaki+
Unraveling SARS-CoV-2 Host-Response Heterogeneity through Longitudinal Molecular Subtyping Hospitalized COVID-19 patients exhibit diverse immune responses during acute infection, which are associated with a wide range of clinical outcomes. However, understanding these immune heterogeneities...- SNT Gatchaman
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- coagulation complement inflammation t cells
- Replies: 0
- Forum: Long Covid research
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Characterization model of the post COVID-19 condition based on immunological, biochemical, and cytokine markers, 2024, Oliván-Blázquez et al.
Characterization model of the post COVID-19 condition based on immunological, biochemical, and cytokine markers Bárbara Oliván-Blázquez; Marta Bona-Otal; Fátima Méndez-López; David Lerma-Irureta; Paula García-Izuel; Jesús Ibáñez-Ruiz; Alberto Montolío; María Ruiz-Herreros; Javier Godino; Beatriz...- SNT Gatchaman
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- coagulation igfbp il-10 nk cells
- Replies: 1
- Forum: Long Covid research
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Fibrin drives thromboinflammation and neuropathology in COVID-19, 2024, Jae Kyu Ryu et al
Abstract Life-threatening thrombotic events and neurological symptoms are prevalent in COVID-19 and are persistent in patients with long COVID experiencing post-acute sequelae of SARS-CoV-2 infection1,2,3,4. Despite the clinical evidence1,5,6,7, the underlying mechanisms of coagulopathy in...- Mij
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- coagulation complement fibrin fibrinogen neuroinflammation nk cells spike protein thromboinflammation
- Replies: 11
- Forum: Long Covid research
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Review Inflammation-, immunothrombosis,- & autoimmune-feedback loops may lead to persistent neutrophil self-stimulation in long COVID, 2024, Thierry & Salmon
Inflammation-, immunothrombosis,- and autoimmune-feedback loops may lead to persistent neutrophil self-stimulation in long COVID Alain R. Thierry; Dominique Salmon Understanding the pathophysiology of long COVID is one of the most intriguing challenges confronting contemporary medicine. Despite...- SNT Gatchaman
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- autoimmunity coagulation neutrophil extracellular traps neutrophils
- Replies: 5
- Forum: Long Covid research
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Monocyte-Mediated Thrombosis Linked to Circulating Tissue Factor and Immune Paralysis in COVID-19, 2024, Goonewardena et al.
Monocyte-Mediated Thrombosis Linked to Circulating Tissue Factor and Immune Paralysis in COVID-19 Sascha N. Goonewardena; Qinzhong Chen; Ashley M. Tate; Olga G. Grushko; Dilna Damodaran; Pennelope K. Blakely; Salim S. Hayek; David J. Pinsky; Robert S. Rosenson BACKGROUND SARS-CoV-2 infections...- SNT Gatchaman
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- coagulation complement immunoparalysis immunothrombosis innate immune system monocytes tissue factor toll-like receptor
- Replies: 1
- Forum: Epidemics (including Covid-19, not Long Covid)
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Trial Report Sex Modifies the Effect of COVID-19 on Arterial Elasticity, 2024, Durieux et al.
Sex Modifies the Effect of COVID-19 on Arterial Elasticity Durieux, Jared C.; Zisis, Sokratis N.; Mouchati, Christian; Labbato, Danielle; Abboud, Marc; McComsey, Grace A. There is limited long-term evidence on the effects of COVID-19 on vascular injury between male and female sex. An adult...- SNT Gatchaman
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- coagulation d-dimer endopat endothelium gut permeability oestrogen sex differences vascular zonulin
- Replies: 1
- Forum: Long Covid research
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[...] LC-MS/MS analysis of ME/CFS plasma reveals dysregulated coagulation [...], endothelial dysfunction, [...], 2024, Nunes, Kell, Pretorius et al
Data-independent LC-MS/MS analysis of ME/CFS plasma reveals a dysregulated coagulation system, endothelial dysfunction, downregulation of complement machinery Massimo Nunes, Mare Vlok, Amy Proal, Douglas B. Kell, Etheresia Pretorius Published 16 July 2024 Abstract Myalgic...- forestglip
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- coagulation complement complement component 9 complement system endothelial function immunoglobulin kell lactotransferrin liquid chromatography tandem mass spectroscopy me/cfs platelet factor 4 platelet-poor plasma pretorius protein s s100 s100-a9 thrombospondin-1
- Replies: 6
- Forum: ME/CFS research
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Preferential and sustained platelet activation in COVID-19 survivors with mental disorders, 2024, Maugeri et al.
Preferential and sustained platelet activation in COVID-19 survivors with mental disorders Maugeri, Norma; De Lorenzo, Rebecca; Mazza, Mario Gennaro; Palladini, Mariagrazia; Ciceri, Fabio; Rovere-Querini, Patrizia; Manfredi, Angelo A.; Benedetti, Francesco Pre-existing mental disorders are...- SNT Gatchaman
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- anxiety cd147 coagulation covid depression p-selectin platelet hyperactivity platelets spike protein thromboinflammation
- Replies: 1
- Forum: Long Covid research
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SARS-CoV-2 spike protein potentiates platelet aggregation via upregulating integrin αIIbβ3 outside-in signaling pathway, 2024, Wang et al.
SARS-CoV-2 spike protein potentiates platelet aggregation via upregulating integrin αIIbβ3 outside-in signaling pathway Wang, Ruijie; Tian, Zezhong; Zhu, Meiyan; Zhang, Bingying; Li, Yanzhang; Zheng, Yiqi; Mao, Yuheng; Zhao, Yimin; Yang, Yan Platelet hyperreactivity is one of the crucial causes...- SNT Gatchaman
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- coagulation covid fibrinogen integrins platelet hyperactivity platelets spike protein
- Replies: 1
- Forum: Epidemics (including Covid-19, not Long Covid)
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Interventional Removal of Travelling Microthrombi Using Targeted Magnetic Microbubble, 2024, Li et al.
Interventional Removal of Travelling Microthrombi Using Targeted Magnetic Microbubble Yongjian Li; Zujie Gao; Xiaobing Zheng; Yunfan Pan; Jinlong Xu; Yan Li; Haosheng Chen Microthrombus is one of the major causes of the sequelae of COVID-19 and leads to subsequent embolism and necrosis. Due to...- SNT Gatchaman
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- coagulation microclots
- Replies: 8
- Forum: Long Covid research
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Differential Gene Expression in the Upper Respiratory Tract following Acute COVID-19 Infection in Ambulatory Patients That Develop [LC], 2024, Biondi+
Differential Gene Expression in the Upper Respiratory Tract following Acute COVID-19 Infection in Ambulatory Patients That Develop Long COVID Biondi, Mia J.; Addo, Mary; Zahoor, Muhammad Atif; Salvant, Elsa; Yip, Paul; Barber, Bethany; Smookler, David; Wasif, Sumaiyah; Gaete, Kayla; Kandel...- SNT Gatchaman
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- coagulation complement cpb2 epigenetics fibrinogen fibrinolysis il-7 kallikreins transcriptomics
- Replies: 9
- Forum: Long Covid research
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[Preprint] Tocilizumab Reduces Hypercoagulation in COVID-19 - Perspectives from Coag-ImmCovA Clinical Trial, 2024, Almskog et al.
Tocilizumab Reduces Hypercoagulation in COVID-19 - Perspectives from The Coagulation and Immunomodulation Covid Assessment Coag-ImmCovA Clinical Trial. Lou M Almskog; Anna Sjostrom; Jonas Sunden-Cullberg; Apostolos Taxiarchis; Anna Agren; Sara Freyland; Madeleine Borjesson; Agneta Wikman; Carl...- SNT Gatchaman
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- coagulation covid 19 il-6 monoclonal antibody
- Replies: 0
- Forum: Epidemics (including Covid-19, not Long Covid)
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Reduction of hemagglutination induced by a SARS-CoV-2 spike protein fragment using an amyloid-binding benzothiazole amphiphile, 2024, Li et al.
Reduction of hemagglutination induced by a SARS-CoV-2 spike protein fragment using an amyloid-binding benzothiazole amphiphile Li, Meihan; Castro Lingl, Sascha; Yang, Jerry COVID-19 infection is associated with a variety of vascular occlusive morbidities. However, a comprehensive understanding...- SNT Gatchaman
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- amyloid coagulation red blood cells spike protein
- Replies: 1
- Forum: Epidemics (including Covid-19, not Long Covid)
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Targeting the High-Density Lipoprotein Proteome for the Treatment of Post-Acute Sequelae of SARS-CoV-2, 2024, Grote et al.
Targeting the High-Density Lipoprotein Proteome for the Treatment of Post-Acute Sequelae of SARS-CoV-2 Grote, Karsten; Schaefer, Ann-Christin; Soufi, Muhidien; Ruppert, Volker; Linne, Uwe; Mukund Bhagwat, Aditya; Szymanski, Witold; Graumann, Johannes; Gercke, Yana; Aldudak, Sümeya...- SNT Gatchaman
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- ace2 actin amyloid atp atp6 coagulation cytoskeleton endothelial cells filamin-a hdl lipids proteomics statins
- Replies: 0
- Forum: Long Covid research
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Preprint Persistent Activation of Chronic Inflammatory Pathways in Long Covid, 2024, Aid et al.
Persistent Activation of Chronic Inflammatory Pathways in Long Covid Malika Aid; Katherine McMahan; Nicole Hachmann; Jessica Miller; Erica Borducchi; David Hope; Marjorie Rowe; Eleanor Schonberg; Siline Thai; Ai-ris Collier; Janet Mullington; Dan Barouch Long Covid, or Post-Acute Sequelae of...- SNT Gatchaman
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- coagulation complement hla-dqb1 inflammation insulin jak-stat lipids mast cells nk cells t cells
- Replies: 4
- Forum: Long Covid research
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Hypothesis Fibrinaloid Microclots and Atrial Fibrillation, 2024, Kell, Lip, Pretorius
Fibrinaloid Microclots and Atrial Fibrillation Kell, Douglas B.; Lip, Gregory Y. H.; Pretorius, Etheresia Atrial fibrillation (AF) is a comorbidity of a variety of other chronic, inflammatory diseases for which fibrinaloid microclots are a known accompaniment (and in some cases, a cause, with a...- SNT Gatchaman
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- amyloid atrial fibrillation coagulation fibrinaloid fibrinolysis microclots
- Replies: 10
- Forum: Other health news and research