coagulation

  1. Mij

    Fibrin drives thromboinflammation and neuropathology in COVID-19, 2024, Jae Kyu Ryu et al

    Abstract Life-threatening thrombotic events and neurological symptoms are prevalent in COVID-19 and are persistent in patients with long COVID experiencing post-acute sequelae of SARS-CoV-2 infection1,2,3,4. Despite the clinical evidence1,5,6,7, the underlying mechanisms of coagulopathy in...
    • Mij
    • Thread
    • coagulation complement fibrin fibrinogen neuroinflammation nk cells spike protein thromboinflammation
    • Replies: 11
    • Forum: Long Covid research
  2. SNT Gatchaman

    Review Inflammation-, immunothrombosis,- & autoimmune-feedback loops may lead to persistent neutrophil self-stimulation in long COVID, 2024, Thierry & Salmon

    Inflammation-, immunothrombosis,- and autoimmune-feedback loops may lead to persistent neutrophil self-stimulation in long COVID Alain R. Thierry; Dominique Salmon Understanding the pathophysiology of long COVID is one of the most intriguing challenges confronting contemporary medicine. Despite...
  3. SNT Gatchaman

    Monocyte-Mediated Thrombosis Linked to Circulating Tissue Factor and Immune Paralysis in COVID-19, 2024, Goonewardena et al.

    Monocyte-Mediated Thrombosis Linked to Circulating Tissue Factor and Immune Paralysis in COVID-19 Sascha N. Goonewardena; Qinzhong Chen; Ashley M. Tate; Olga G. Grushko; Dilna Damodaran; Pennelope K. Blakely; Salim S. Hayek; David J. Pinsky; Robert S. Rosenson BACKGROUND SARS-CoV-2 infections...
  4. SNT Gatchaman

    Trial Report Sex Modifies the Effect of COVID-19 on Arterial Elasticity, 2024, Durieux et al.

    Sex Modifies the Effect of COVID-19 on Arterial Elasticity Durieux, Jared C.; Zisis, Sokratis N.; Mouchati, Christian; Labbato, Danielle; Abboud, Marc; McComsey, Grace A. There is limited long-term evidence on the effects of COVID-19 on vascular injury between male and female sex. An adult...
    • SNT Gatchaman
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    • coagulation d-dimer endopat endothelium gut permeability oestrogen sex differences vascular zonulin
    • Replies: 1
    • Forum: Long Covid research
  5. forestglip

    [...] LC-MS/MS analysis of ME/CFS plasma reveals dysregulated coagulation [...], endothelial dysfunction, [...], 2024, Nunes, Kell, Pretorius et al

    Data-independent LC-MS/MS analysis of ME/CFS plasma reveals a dysregulated coagulation system, endothelial dysfunction, downregulation of complement machinery Massimo Nunes, Mare Vlok, Amy Proal, Douglas B. Kell, Etheresia Pretorius Published 16 July 2024 Abstract Myalgic...
    • forestglip
    • Thread
    • coagulation complement complement component 9 complement system endothelial function immunoglobulin kell lactotransferrin liquid chromatography tandem mass spectroscopy me/cfs platelet factor 4 platelet-poor plasma pretorius protein s s100 s100-a9 thrombospondin-1
    • Replies: 6
    • Forum: ME/CFS research
  6. SNT Gatchaman

    Preferential and sustained platelet activation in COVID-19 survivors with mental disorders, 2024, Maugeri et al.

    Preferential and sustained platelet activation in COVID-19 survivors with mental disorders Maugeri, Norma; De Lorenzo, Rebecca; Mazza, Mario Gennaro; Palladini, Mariagrazia; Ciceri, Fabio; Rovere-Querini, Patrizia; Manfredi, Angelo A.; Benedetti, Francesco Pre-existing mental disorders are...
    • SNT Gatchaman
    • Thread
    • anxiety cd147 coagulation covid depression p-selectin platelet hyperactivity platelets spike protein thromboinflammation
    • Replies: 1
    • Forum: Long Covid research
  7. SNT Gatchaman

    SARS-CoV-2 spike protein potentiates platelet aggregation via upregulating integrin αIIbβ3 outside-in signaling pathway, 2024, Wang et al.

    SARS-CoV-2 spike protein potentiates platelet aggregation via upregulating integrin αIIbβ3 outside-in signaling pathway Wang, Ruijie; Tian, Zezhong; Zhu, Meiyan; Zhang, Bingying; Li, Yanzhang; Zheng, Yiqi; Mao, Yuheng; Zhao, Yimin; Yang, Yan Platelet hyperreactivity is one of the crucial causes...
  8. SNT Gatchaman

    Interventional Removal of Travelling Microthrombi Using Targeted Magnetic Microbubble, 2024, Li et al.

    Interventional Removal of Travelling Microthrombi Using Targeted Magnetic Microbubble Yongjian Li; Zujie Gao; Xiaobing Zheng; Yunfan Pan; Jinlong Xu; Yan Li; Haosheng Chen Microthrombus is one of the major causes of the sequelae of COVID-19 and leads to subsequent embolism and necrosis. Due to...
  9. SNT Gatchaman

    Differential Gene Expression in the Upper Respiratory Tract following Acute COVID-19 Infection in Ambulatory Patients That Develop [LC], 2024, Biondi+

    Differential Gene Expression in the Upper Respiratory Tract following Acute COVID-19 Infection in Ambulatory Patients That Develop Long COVID Biondi, Mia J.; Addo, Mary; Zahoor, Muhammad Atif; Salvant, Elsa; Yip, Paul; Barber, Bethany; Smookler, David; Wasif, Sumaiyah; Gaete, Kayla; Kandel...
    • SNT Gatchaman
    • Thread
    • coagulation complement cpb2 epigenetics fibrinogen fibrinolysis il-7 kallikreins transcriptomics
    • Replies: 9
    • Forum: Long Covid research
  10. SNT Gatchaman

    [Preprint] Tocilizumab Reduces Hypercoagulation in COVID-19 - Perspectives from Coag-ImmCovA Clinical Trial, 2024, Almskog et al.

    Tocilizumab Reduces Hypercoagulation in COVID-19 - Perspectives from The Coagulation and Immunomodulation Covid Assessment Coag-ImmCovA Clinical Trial. Lou M Almskog; Anna Sjostrom; Jonas Sunden-Cullberg; Apostolos Taxiarchis; Anna Agren; Sara Freyland; Madeleine Borjesson; Agneta Wikman; Carl...
  11. SNT Gatchaman

    Reduction of hemagglutination induced by a SARS-CoV-2 spike protein fragment using an amyloid-binding benzothiazole amphiphile, 2024, Li et al.

    Reduction of hemagglutination induced by a SARS-CoV-2 spike protein fragment using an amyloid-binding benzothiazole amphiphile Li, Meihan; Castro Lingl, Sascha; Yang, Jerry COVID-19 infection is associated with a variety of vascular occlusive morbidities. However, a comprehensive understanding...
  12. SNT Gatchaman

    Targeting the High-Density Lipoprotein Proteome for the Treatment of Post-Acute Sequelae of SARS-CoV-2, 2024, Grote et al.

    Targeting the High-Density Lipoprotein Proteome for the Treatment of Post-Acute Sequelae of SARS-CoV-2 Grote, Karsten; Schaefer, Ann-Christin; Soufi, Muhidien; Ruppert, Volker; Linne, Uwe; Mukund Bhagwat, Aditya; Szymanski, Witold; Graumann, Johannes; Gercke, Yana; Aldudak, Sümeya...
    • SNT Gatchaman
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    • ace2 actin amyloid atp atp6 coagulation cytoskeleton endothelial cells filamin-a hdl lipids proteomics statins
    • Replies: 0
    • Forum: Long Covid research
  13. SNT Gatchaman

    Preprint Persistent Activation of Chronic Inflammatory Pathways in Long Covid, 2024, Aid et al.

    Persistent Activation of Chronic Inflammatory Pathways in Long Covid Malika Aid; Katherine McMahan; Nicole Hachmann; Jessica Miller; Erica Borducchi; David Hope; Marjorie Rowe; Eleanor Schonberg; Siline Thai; Ai-ris Collier; Janet Mullington; Dan Barouch Long Covid, or Post-Acute Sequelae of...
    • SNT Gatchaman
    • Thread
    • coagulation complement hla-dqb1 inflammation insulin jak-stat lipids mast cells nk cells t cells
    • Replies: 4
    • Forum: Long Covid research
  14. SNT Gatchaman

    Hypothesis Fibrinaloid Microclots and Atrial Fibrillation, 2024, Kell, Lip, Pretorius

    Fibrinaloid Microclots and Atrial Fibrillation Kell, Douglas B.; Lip, Gregory Y. H.; Pretorius, Etheresia Atrial fibrillation (AF) is a comorbidity of a variety of other chronic, inflammatory diseases for which fibrinaloid microclots are a known accompaniment (and in some cases, a cause, with a...
  15. SNT Gatchaman

    Review The Role of Heparin in Postural Orthostatic Tachycardia Syndrome and Other Post-Acute Sequelae of COVID-19, 2024, Gómez-Moyano et al.

    The Role of Heparin in Postural Orthostatic Tachycardia Syndrome and Other Post-Acute Sequelae of COVID-19 Gómez-Moyano, Elisabeth; Pavón-Morón, Javier; Rodríguez-Capitán, Jorge; Bardán-Rebollar, Daniel; Ramos-Carrera, Teresa; Villalobos-Sánchez, Aurora; Pérez de Pedro, Iván; Ruiz-García...
  16. SNT Gatchaman

    Cardiovascular symptoms of PASC are associated with trace-level cytokines that affect function of stem cell derived cardiomyocytes, 2024, Sinclair+

    Now published: Cardiovascular symptoms of PASC are associated with trace-level cytokines that affect function of stem cell derived cardiomyocytes, 2024, Sinclair+']link here[/URL] Preprint Cardiovascular symptoms of PASC are associated with trace-level cytokines that affect the function of...
    • SNT Gatchaman
    • Thread
    • antimicrobial peptides cardiac clusterin coagulation complement cytokines interferon nanotechnology profilin raman stem cells
    • Replies: 4
    • Forum: Long Covid research
  17. SNT Gatchaman

    Persistent hypofibrinolysis in severe COVID-19 associated with elevated fibrinolysis inhibitors activity, 2024, Okazaki et al.

    Persistent hypofibrinolysis in severe COVID-19 associated with elevated fibrinolysis inhibitors activity Okazaki, Erica; Barion, Bárbara Gomes; da Rocha, Tania Rubia Flores; Di Giacomo, Giovanna; Ho, Yeh-Li; Rothschild, Cynthia; Fatobene, Giancarlo; de Carvalho Moraes, Bruna del Guerra...
  18. SNT Gatchaman

    Review Rethinking coagulation: from enzymatic cascade and cell-based reactions to a convergent model involving innate immune activation, 2023, Yong, Jun and

    Rethinking coagulation: from enzymatic cascade and cell-based reactions to a convergent model involving innate immune activation Yong, Jun; Toh, Cheng-Hock Advancements in the conceptual thinking of hemostasis and thrombosis have been catalyzed by major developments within health research over...
  19. SNT Gatchaman

    Amyloid-Fibrinogen Aggregates Microclots Predict Risks of Disseminated Intravascular Coagulation and Mortality, 2024, Schofield et al.

    Amyloid-Fibrinogen Aggregates Microclots Predict Risks of Disseminated Intravascular Coagulation and Mortality Schofield, Jeremy; Abrams, Simon Timothy; Jenkins, Rosalind; Lane, Steven; Wang, Guozheng; Toh, Cheng-Hock Microclots have been associated with various conditions, including post-acute...
  20. SNT Gatchaman

    Blood–brain barrier disruption and sustained systemic inflammation in individuals with long COVID-associated cognitive impairment, 2024, Greene et al

    Preprint Blood-brain barrier disruption in Long COVID-associated cognitive impairment Chris Greene, Ruairi Connolly, Declan Brennan, Aoife Laffan, Eoin O'Keeffe, Lilia Zaporojan, Emma Connolly, Cliona Ni Cheallaigh, Niall Conlon, Colin Doherty, Matthew Campbell Vascular disruption has been...
    • SNT Gatchaman
    • Thread
    • blood brain barrier brain imaging coagulation csf dce-mri endothelial gfap icam-1 inflammation long covid long covid clinic mri p-selectin pf4 platelets s100 scam-1 spike protein t cells tgf-beta tnf
    • Replies: 44
    • Forum: Long Covid research
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