fatigue

mGluR5 mediates post-radiotherapy fatigue development in cancer patients https://www.nature.com/articles/s41398-018-0161-3 In essence, a genetic vulnerability primes the immune system to an inflammatory reponse to radiotherapy in those who develop long term fatigue. Interestingly these...

Lipid profile is associated with decreased fatigue in individuals with progressive multiple sclerosis following a diet-based intervention: Results from a pilot study https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0218075 Popular article...

Download the MSQLI: A User’s Manual (PDF) https://www.nationalmssociety.org/For-Professionals/Researchers/Resources-for-Researchers/Clinical-Study-Measures/Modified-Fatigue-Impact-Scale-(MFIS) Fatigue Impact Scale (Fisk et al, 1994b)...

All sounds very familiar. I wish there were another word to encompass these symptoms. I note they use the term 'pathological fatigue'.........

Cardiopulmonary Physical Therapy Journal Reproducibility of Measurements Obtained During Cardiopulmonary Exercise Testing in Individuals With Fatiguing Health Conditions - Benjamin Larson, Todd Davenport, Staci Stevens, Jared Stevens, Mark Van Ness, Christopher Snell Purpose: Measurements...

https://multiplesclerosisnewstoday.com/news-posts/2019/08/26/persistent-ms-related-fatigue-linked-to-damage-in-specific-brain-regions/ Study here https://journals.sagepub.com/doi/10.1177/1352458519869185

Inflammation and fatigue in early, untreated Parkinson's Disease Abstract Objectives Parkinson's disease (PD)‐related fatigue is a significant clinical problem, and the pathological processes that cause fatigue remain unknown. The aim of the present study was to explore the possible association...

Matcham, F., Ali, S., Irving, K., & Chalder, T. (2019). Psychological predictors of fatigue, work and social adjustment, and psychological distress in rheumatology outpatients: A short report. European Journal of Health Psychology, 26(1), 25-29. https://psycnet.apa.org/record/2019-31300-004

There are a number of references to chronic fatigue syndrome in this paper, including in the abstract, so I thought I would post it here, particularly given that Systrom is a co-author. He is now doing some ME/CFS research in the US. Free full text...

Nancy Klimas is a named author on this. Paywall, https://www.sciencedirect.com/science/article/abs/pii/S0277953619303776 Sci hub, https://sci-hub.se/10.1016/j.socscimed.2019.112392

So, I'm sure many of us are familiar with the idea of establishing an activity baseline, which is where the activity that you are able to manage doesn't trigger PEM. I would argue though that the concept of a baseline is inherently dangerous for PwME as it implies a position that can then be...

Opinion Piece Abstract seemed well thought out... until the last bit open access https://www.wjgnet.com/1007-9327/full/v25/i28/3669.htm

Not a new article, but I was struck by this comment on the relation between fatigue and pro-inflammatory cytokines: link to the article here There are are no consistently observed associations between fatigue in ME and levels of pro-inflammatory cytokines. But its interesting to see we're not...

Open access, https://journals.sagepub.com/doi/10.1177/2050312119850390

Open access at https://jneuroinflammation.biomedcentral.com/articles/10.1186/s12974-019-1502-8

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6003444/ Fig. 5 looks pretty good. Anybody try this?

https://link.springer.com/article/10.1007%2Fs11682-019-00119-2

I don't think this article from yesterday has been shared yet on the forum? Nice to see coverage from Canada. White Rock woman shares her struggle with "horrendous" fatigue A report from the Myalgic Encephalomyelitis & Fibromyalgia Society of BC says that Canadian ME research is “essentially...

FYI https://www.nytimes.com/2019/04/13/health/implant-brain-injury.html?action=click&module=Discovery&pgtype=Homepage Wonder what the cost is.... Surgery done at Stanford

Havana Syndrome: U.S. and Canadian diplomats targeted with possible weapon causing brain injury and neurological symptoms CBS News/60 Minutes main story/video https://www.cbsnews.com/news/brain-trauma-suffered-by-u-s-diplomats-abroad-could-be-work-of-hostile-foreign-government-60-minutes/ CBS...