Phytochemical Modulators of Nociception: A Review of Cannabis Terpenes in Chronic Pain Syndromes
Abstract
Cannabis sativa L. is a phytochemically rich plant with therapeutic potential across various clinical domains, including pain, inflammation, and neurological disorders.
Among its...
Pain Neuroscience Education als Intervention zur Verbesserung der Lebensqualität bei Patienten mit chronischen Kreuzschmerzen
Irle, Lisa; Alfuth, Martin
Abstract
Background
Educational strategies that improve understanding of pain can influence the behaviour of patients with chronic low back...
Modulating neuroplasticity for chronic pain relief: noninvasive neuromodulation as a promising approach
Abstract
Abstract Chronic neuropathic pain is a debilitating neuroplastic disorder that notably impacts the quality of life of millions of people worldwide.
This complex condition...
Adieu to an aphorism: why nociception is necessary for pain
Weisman, Asaf; Quintner, John; Cohen, Milton
Abstract
An aphorism is a short saying intended to express a general truth.
In this article, the popular aphorism, 'nociception is neither necessary nor sufficient for pain', is critically...
Investigation of MMP-3, IL-6, IL-6R, and TNF-Alpha Levels in Fibromyalgia Patients Presenting to a Physical Medicine and Rehabilitation Clinic
Background
Fibromyalgia syndrome (FMS) is a syndrome that commonly affects the musculoskeletal system and is characterized by fatigue and body aches...
Sociodemographic Characteristics and Comorbidities of Primary Fibromyalgia: A Cross-Sectional Study
Introduction
Fibromyalgia (FM) is a chronic condition characterized by widespread musculoskeletal pain, fatigue, cognitive disturbances, and multiple somatic symptoms. However, data on primary...
Gene expression alterations at baseline and following moderate exercise in patients with Chronic Fatigue Syndrome and Fibromyalgia Syndrome
Abstract
Objectives. To determine mRNA expression differences in genes involved in signalling and modulating sensory fatigue, and muscle pain in patients...
Poster abstract from the EULAR rheumatology conference -
EFFICACY OF LOW-DOSE NALTREXONE FOR FIBROMYALGIA: A RANDOMISED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL WITH 12 MONTHS OF FOLLOW-UP (Luciano et al., 2026)
Low-Dose Naltrexone Fails to Outperform Placebo for Pain in Fibromyalgia Treatment...
Fibromyalgia, perfectionism, and interpersonal style. Further evidence for a person-centered approach
Maes, Frank; Vanaerschot, Greet; Goossens, Els; Houdenhove, Boudewijn Van
Objectives
We carried out a controlled, cross-sectional investigation in patients with Fibromyalgia (FM) to determine...
Shared genetic risk between functional somatic syndromes, internalizing disorders, and immune-mediated diseases: a twin-sibling study
Highlights
• We analyzed healthcare data from over 6 million Swedish individuals.
• We used twin-sibling modeling to disentangle genetic and...
Full title: A systematic scoping review and conceptual analysis of new-onset fibromyalgia manifestations after non-hospitalized COVID-19: empirics, definitions, methodologies, pathophysiology, mapping of literature, and knowledge gaps
Abstract
Background
The global coronavirus pandemic has led...
Abstract
Background:
There is growing evidence suggesting a bidirectional relationship between fibromyalgia and migraine. The aim of this work was to study the impact of fibromyalgia on the frequency and severity of migraine headache attacks and the psychological burden in patients with...
Autonomic dysfunction in fibromyalgia syndrome: the role of small fiber damage
Abstract
Abstract
Objective: Cardiovascular autonomic symptoms, particularly orthostatic intolerance, are frequent in fibromyalgia syndrome (FMS) and markedly contribute to disability, yet their underlying...
The influence of Mitoq on symptoms and cognition in fibromyalgia, myalgic encephalomyelitis and chronic fatigue
Cort Johnson; Grant, Joshua
Abstract
Fibromyalgia (FM), myalgic encephalomyelitis (ME) and chronic fatigue syndrome (CFS) are disorders with similar symptom- constellations including...
Resolution of fibromyalgia by controlling obstructive sleep apnea with a mandibular advancement device
Fernanda Vantine, Dominik Ettlin, Miguel Meira-e-Cruz
https://pmc.ncbi.nlm.nih.gov/articles/PMC8848527/ (PDF available)
Abstract
Fibromyalgia (FM) is a chronic, often disabling disorder...
Obstructive sleep apnea syndrome as an uncommon cause of fibromyalgia: a case report
Vesile Sepici, Aliye Tosun, Oğuz Köktürk
https://link.springer.com/article/10.1007/s00296-007-0375-9
Sci-Hub link: https://sci-hub.st/10.1007/s00296-007-0375-9
Abstract
Fibromyalgia syndrome (FMS) is...
Inspiratory Airflow Dynamics During Sleep in Women with Fibromyalgia
Avram R Gold, Francis Dipalo, Morris S Gold, Joan Broderick
https://www.researchgate.net/publication/8541375_Inspiratory_Airflow_Dynamics_During_Sleep_in_Women_with_Fibromyalgia (PDF Available)
Study objectives: To determine...
Key Points
Question Is transcutaneous electrical nerve stimulation (TENS) effective for treating pain when combined with physical therapy (PT) in individuals with fibromyalgia?
Findings This cluster randomized clinical trial of 459 participants with fibromyalgia from 28 PT clinics from 6...
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