hypothalamus

  1. C

    Nature: A preoptic neuronal population controls fever and appetite during sickness, 2022, Osterhout et al

    A preoptic neuronal population controls fever and appetite during sickness Osterhout, Kapoor, Eichhorn, Vaughn, Moore, Ding Liu, Lee, DeNardo, Liqun Luo, Xiaowei Zhuan, Dulac Abstract During infection, animals exhibit adaptive changes in physiology and behaviour aimed at increasing...
  2. Andy

    A Paradigm for Post-Covid-19 Fatigue Syndrome Analogous to ME/CFS, 2021, Mackay

    A significant proportion of COVID-19 patients are suffering from prolonged Post-COVID-19 Fatigue Syndrome, with characteristics typically found in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). However, no clear pathophysiological explanation, as yet, has been provided. A novel...
  3. Andy

    Hypothalamic-Pituitary autoimmunity and related impairment of hormone secretions in chronic fatigue syndrome, 2021, De Bellis, Montoya et al

    Abstract Context Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a severe chronic illness which reduces the quality of life. A potential role of neuroendocrine autoimmune dysfunction has been hypothesized. Objective To investigate the occurrence of anti-pituitary (APA) and...
  4. B

    Hypothesis: Mechanisms That Prevent Recovery in Prolonged ICU Patients Also Underlie ME/CFS: 2021, Stanculescu, Larsson and Bergquist

    https://www.frontiersin.org/articles/10.3389/fmed.2021.628029/full?utm_source=F-NTF&utm_medium=EMLX&utm_campaign=PRD_FEOPS_20170000_ARTICLE Here the hypothesis is advanced that maladaptive mechanisms that prevent recovery in some intensive care unit (ICU) patients may also underlie Myalgic...
  5. R

    A neuro-inflammatory model can explain the onset, symptoms and flare-ups of ME/CFS, 2019, Mackay

    This research article in the Journal of The Royal New Zealand College of General Practitioners has just been brought to my attention... http://www.publish.csiro.au/HC/fulltext/HC19041 A neuro-inflammatory model can explain the onset, symptoms and flare-ups of myalgic encephalomyelitis/chronic...
  6. adambeyoncelowe

    A compromised paraventricular nucleus within a dysfunctional hypothalamus: A novel neuroinflammatory paradigm for ME/CFS, 2018, Mackay, Tate.

    A compromised paraventricular nucleus within a dysfunctional hypothalamus: A novel neuroinflammatory paradigm for ME/CFS Angus MackayWarren P Tate First Published December 6, 2018 https://doi.org/10.1177/2058738418812342 Bolding in the quoted text mine for clarity.
  7. Hip

    The buspirone challenge test clearly distinguishes ME/CFS patients from healthy controls: why is it not being developed and deployed?

    Moderator note: Link to @forestglip's excellent summary of what is known, as of August 2026, about the prolactin response to a buspirone challenge in ME/CFS here See also a Google document where some members are compiling findings and ideas related to prolactin response here. ******** I...
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