il-6

  1. forestglip

    Seasonal variation in the associations between self-reported long-COVID symptoms and IL-6 signalling-related factors [...], 2025, Rees et al

    Seasonal variation in the associations between self-reported long-COVID symptoms and IL-6 signalling-related factors (particularly the rs2228145 variant of the IL-6R gene): A clinical study. Katie Rees, Rebecca Aicheler, Lee Butcher, Alan Dodd, John Geen, Ceri Lynch, Isabel Massey, Keith...
  2. Mij

    Cellular deconstruction of the human skeletal muscle microenvironment identifies an exercise-induced histaminergic crosstalk,2025,Van der Stede et al

    Highlights Mononuclear cells are primary drivers of the exercise response in skeletal muscle • Release of histamine from skeletal muscle during exercise from mast cells • Histamine receptor antagonists impair post-exercise muscle glycogen resynthesis • Exercise-induced transcriptional...
    • Mij
    • Thread
    • bdnf biopsy exercise glucose histamine il-6 insulin jak-stat mapk mast cells p53 tgf-β tnf
    • Replies: 8
    • Forum: Other health news and research
  3. Yann04

    [Preprint] Unravelling the Impact of SARS-CoV-2 on Hemostatic and Complement Systems: A Systems Immunology Perspective, 2024, Murad et al

    Abstract: The hemostatic system prevents and stops bleeding, maintaining circulatory integrity after injury. It directly interacts with the complement system, which is key to innate immunity. In coronavirus disease 2019 (COVID-19), dysregulation of the hemostatic and complement systems has been...
  4. forestglip

    Association of inflammation cytokines with cognitive function in first-episode major depressive disorder, 2024, Wang et al

    Association of inflammation cytokines with cognitive function in first-episode major depressive disorder Yanfang Wang, Yanqing Xi, Zongqi Wang, Guojuan Li, Zhuoqun Hao, Jiahui Nie, Jinxiang Li, Yuting Tan, Xiaodong Hu, Genwei Wang, Sha Liu [Provisionally accepted] Abstract Abnormal cognitive...
  5. forestglip

    Exploring the landscape of symptom-specific inflammatory cytokines in post-COVID syndrome patients, 2024, Tilikete et al

    Exploring the landscape of symptom-specific inflammatory cytokines in post-COVID syndrome patients Chafik Tilikete, Imen Zamali, Zeineb Meddeb, Ghassen Kharroubi, Soumaya Marzouki, Tarak Dhaouadi, Ahlem Ben Hmid, Samar Samoud, Yousr Galai, Selma Charfeddine, Leila Abid, Salem Abdessalem, Jihène...
    • forestglip
    • Thread
    • acute infection cytokines dyspnea endothelial dysfunction fatigue ifny il-10 il-12p70 il-1a il-1b il-27 il-6 il-8 inflammation ip-10 long covid mcp-1 memory tnfa
    • Replies: 0
    • Forum: Long Covid research
  6. Mij

    CCL2-mediated endothelial injury drives cardiac dysfunction in long COVID, 2024, Dilip Thomas et al

    Abstract Evidence linking the endothelium to cardiac injury in long coronavirus disease (COVID) is well documented, but the underlying mechanisms remain unknown. Here we show that cytokines released by endothelial cells (ECs) contribute to long-COVID-associated cardiac dysfunction. Using...
    • Mij
    • Thread
    • acetylcholine calcium cardiac ccl2 cytokines endothelial cells endotheliitis fibronectin glycocalyx il-6 monocytes nf-κb nitric oxide post-translational modification spike protein
    • Replies: 4
    • Forum: Long Covid research
  7. SNT Gatchaman

    Immune system adaptation during gender-affirming testosterone treatment, 2024, Lakshmikanth, Brodin et al.

    Immune system adaptation during gender-affirming testosterone treatment Lakshmikanth, Tadepally; Consiglio, Camila; Sardh, Fabian; Forlin, Rikard; Wang, Jun; Tan, Ziyang; Barcenilla, Hugo; Rodriguez, Lucie; Sugrue, Jamie; Noori, Peri; Ivanchenko, Margarita; Piñero Páez, Laura; Gonzalez, Laura...
  8. SNT Gatchaman

    Effects of physical training on coagulation parameters, IL-6, and ACE-2 in COVID-19 survivors, 2024, Binabaji et al.

    Effects of physical training on coagulation parameters, interleukin-6, and angiotensin-converting enzyme-2 in COVID-19 survivors Binabaji, Soheila; Rahimi, Mohammad; Rajabi, Hamid; Keshavarz, Mohsen; Rahimi, Rahimeh; Ahmadi, Azam; Gahreman, Daniel COVID-19 is a highly contagious virus that uses...
  9. forestglip

    Preprint Clinical and Diagnostic Features of Post-Acute COVID-19 Vaccination Syndrome (PACVS), 2024, Mundorf et al

    Clinical and Diagnostic Features of Post-Acute COVID-19 Vaccination Syndrome (PACVS) Anna Katharina Mundorf, Amelie Semmler, Harald Heidecke, Matthias Schott, Falk Steffen, Stefan Bittner, Karl J. Lackner, Karin Schulze-Bosse, Marc Pawlitzki, Sven Guenther Meuth, Frank Klawonn, Jana Ruhrländer...
  10. SNT Gatchaman

    [Preprint] Tocilizumab Reduces Hypercoagulation in COVID-19 - Perspectives from Coag-ImmCovA Clinical Trial, 2024, Almskog et al.

    Tocilizumab Reduces Hypercoagulation in COVID-19 - Perspectives from The Coagulation and Immunomodulation Covid Assessment Coag-ImmCovA Clinical Trial. Lou M Almskog; Anna Sjostrom; Jonas Sunden-Cullberg; Apostolos Taxiarchis; Anna Agren; Sara Freyland; Madeleine Borjesson; Agneta Wikman; Carl...
  11. SNT Gatchaman

    Extreme γ′ fibrinogen levels in COVID-19 patients, 2024, Hudkins et al.

    Extreme γ′ fibrinogen levels in COVID-19 patients Hudkins; Hamilton; Underwood; Kazmierczak; Dewey; Kazmierczak; Messer; Khan; Schreiber; Farrell COVID-19 disease progression can be accompanied by a “cytokine storm” that leads to secondary sequelae such as acute respiratory distress syndrome...
  12. SNT Gatchaman

    Preprint Alpha7 nicotinic acetylcholine receptor agonist PHA 568487 dampens inflammation in PBMCs from patients with coronary artery disease, 2024, Mjörnstedt+

    Alpha7 nicotinic acetylcholine receptor agonist PHA 568487 dampens inflammation in PBMCs from patients with newly discovered coronary artery disease. Filip Mjörnstedt; Rebecka Wilhelmsson; Marcus Ulleryd; Maria Hammarlund; Göran Bergström; Anders Gummesson; Maria E Johansson BACKGROUND The...
  13. SNT Gatchaman

    Severe COVID-19 and long COVID are associated with high expression of STING, cGAS and IFN-α, 2024, Queiroz et al.

    Severe COVID-19 and long COVID are associated with high expression of STING, cGAS and IFN-α Queiroz, Maria Alice Freitas; Brito, Wandrey Roberto dos Santos; Pereira, Keise Adrielle Santos; Pereira, Leonn Mendes Soares; Amoras, Ednelza da Silva Graça; Lima, Sandra Souza; Santos, Erika Ferreira...
  14. SNT Gatchaman

    Cytokines IL1β, IL6, TNFα & serum cortisol may not constitute reliable biomarkers to identify [PASC], 2024, Fleischer, Kleinschnitz et al.

    Cytokines IL1β, IL6, TNFα and serum cortisol levels may not constitute reliable biomarkers to identify individuals with post-acute sequelae of COVID-19 Michael Fleischer; Fabian Szepanowski; Anne K Mausberg; Livia Asan; Ellen Uslar; Denise Zwanziger; Lothar Volbracht; Mark Stettner; Christoph...
  15. SNT Gatchaman

    Viral afterlife: SARS-CoV-2 as a reservoir of immunomimetic peptides that reassemble into proinflammatory supramolecular complexes, 2024, Zhang et al.

    Viral afterlife: SARS-CoV-2 as a reservoir of immunomimetic peptides that reassemble into proinflammatory supramolecular complexes Zhang, Yue; Bharathi, Vanthana; Dokoshi, Tatsuya; de Anda, Jaime; Ursery, Lauryn Tumey; Kulkarni, Nikhil N.; Nakamura, Yoshiyuki; Chen, Jonathan; Luo, Elizabeth W...
    • SNT Gatchaman
    • Thread
    • amyloid antimicrobial peptides cathelicidin il-6 inflammation mmp-9 molecular mimicry pamps sars-cov-2 transcriptome
    • Replies: 13
    • Forum: Long Covid research
  16. SNT Gatchaman

    Near-Infrared Light Exposure Triggers ROS to Downregulate Inflammatory Cytokines Induced by SARS Spike Protein in Human Cell Culture, 2023, Aguida +

    Near-Infrared Light Exposure Triggers ROS to Downregulate Inflammatory Cytokines Induced by SARS-CoV-2 Spike Protein in Human Cell Culture Aguida, Blanche; Chabi, Marie-Marthe; Baouz, Soria; Mould, Rhys; Bell, Jimmy D.; Pooam, Marootpong; André, Sebastien; Archambault, Dominique; Ahmad...
  17. SNT Gatchaman

    Preliminary Evidence of the Differential Expression of HERVs in Kawasaki Disease and SARS-CoV-2-Associated MIS-C, 2023, Balestrieri et al.

    Preliminary Evidence of the Differential Expression of Human Endogenous Retroviruses in Kawasaki Disease and SARS-CoV-2-Associated Multisystem Inflammatory Syndrome in Children Balestrieri, Emanuela; Corinaldesi, Elena; Fabi, Marianna; Cipriani, Chiara; Giudice, Martina; Conti, Allegra...
    • SNT Gatchaman
    • Thread
    • children herv herv-k herv-w il-6 kawasaki mis-c nf-κb retrovirus sars-cov-2 spike protein syncitin tlr-4
    • Replies: 0
    • Forum: Long Covid research
  18. SNT Gatchaman

    Preprint A 50-gene high-risk profile predictive of COVID & pulmonary fibrosis mortality from molecular imbalance in monocyte & T-cell subsets, 2023, Tourki +

    A 50-gene high-risk profile predictive of COVID-19 and Idiopathic Pulmonary Fibrosis mortality originates from a molecular imbalance in monocyte and T-cell subsets that reverses in survivors with post-COVID-19 Interstitial Lung Disease Bochra Tourki; Minxue Jia; Theodoros Karampitsakos; Iset M...
    • SNT Gatchaman
    • Thread
    • cd163 fibrosis gene expression hspc il-6 ild ipf lung fibrosis lungs monocytes pbmc sars-cov-2 tgf-beta
    • Replies: 2
    • Forum: Long Covid research
  19. SNT Gatchaman

    Preprint SARS-CoV-2 induces acute neurological signs while CGRP signaling blockade reduces IL-6 release and weight loss in mouse models, 2023, Rahman et al.

    SARS-CoV-2 induces acute neurological signs while Calcitonin Gene-Related Peptide CGRP signaling blockade reduces interleukin 6 IL-6 release and weight loss in mouse models Shafaqat M Rahman; David W Buchholz; Brian Imbiakha; Mason C Jaeger; Justin Leach; Raven M Osborn; Ann O Birmingham...
  20. SNT Gatchaman

    A myeloid program associated with COVID-19 severity is decreased by therapeutic blockade of IL-6 signaling, 2023, Hackney et al.

    A myeloid program associated with COVID-19 severity is decreased by therapeutic blockade of IL-6 signaling Altered myeloid inflammation and lymphopenia are hallmarks of severe infections. We identified the upregulated EN-RAGE gene program in airway and blood myeloid cells from patients with...
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