An ad is currently being circulated in Swedish ME groups on social media, a research study led by prof Jonas Bergquist at Uppsala University that is currently recruiting.
It's a study on altered energy metabolism in ME/CFS, focusing mainly on lactate, glucose and hypoxanthine.
(I couldn't find...
Abstract
Background
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a complex and debilitating disease accompanied by muscular fatigue and pain. A functional measure to assess muscle fatigability of ME/CFS patients is, however, not established in clinical routine. The aim of this...
Abstract
Chronic fatigue syndrome (CFS) is a complex illness, which is often misdiagnosed as a psychiatric illness. In two previous reports, using 1H MRSI, we found significantly higher levels of ventricular cerebrospinal fluid (CSF) lactate in patients with CFS relative to those with...
Meta-omics analysis of elite athletes identifies a performance-enhancing microbe that functions via lactate metabolism - Jonathan Scheiman et al
The human gut microbiome is linked to many states of human health and disease1. The metabolic repertoire of the gut micro-biome is vast, but the...
Title:Suggested Pathology of Systemic Exertion Intolerance Disease: Impairment ofthe E3 Subunit or Crossover of Swinging Arms of the E2 Subunit of the Pyruvate Dehydrogenase Complex Decreases Regeneration of Cofactor DihydrolipoicAcid of the E2 Subunit
Abtract:Systemic Exertion Intolerance...
Physiological Reports Abnormal blood lactate accumulation during repeated exercise testing in myalgic encephalomyelitis/chronic fatigue syndrome by Katarina Lien et al
Abstract
Post‐exertional malaise and delayed recovery are hallmark symptoms of myalgic encephalomyelitis/chronic fatigue...
As this came up in a different thread, I thought it would be worth creating a separate thread for it.
Open access at https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3946674/
In vivo lactate imaging for atherosclerosis.
Could this technique work for pwme, particularly after exercise challenge given the same aerobic/ anearobic energy shift?
http://heart.bmj.com/content/early/2018/04/27/heartjnl-2017-312356
Paywalled at http://www.tandfonline.com/doi/abs/10.1080/21641846.2017.1280114?journalCode=rftg20
Study is from Feb 2017 but Solve have just posted a review of it:
http://solvecfs.org/elevations-of-ventricular-lactate-levels-occur-in-both-chronic-fatigue-syndrome-and-fibromyalgia/
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