long covid

Abstract Post-acute sequelae of Covid-19 (PASC) refer to persistent symptoms lasting weeks to months after acute SARS-CoV-2 infection. However, identifying biological mechanisms, potential therapeutic targets, and modifiable environmental risk factors remains necessary. Here, we analyzed...

Full title: Prevalence of Circulating Autoantibodies Against G-Protein-Coupled Receptors as Potential Biomarkers for Long COVID: Preliminary Investigations Abstract This prospective, single-center, case-control study investigated circulating autoantibodies (AAbs) targeting G protein-coupled...

Emily Taylor, President and Chief Executive Officer of Solve M.E., discusses the significant socioeconomic burden of Long COVID, highlighting advances in research that can improve understanding of Long COVID and enable targeted interventions and better treatment protocols Long COVID is an...

Abstract: Cognitive dysfunction is a symptom of Long COVID. To characterize functional connectivity changes that may contribute to cognitive dysfunction in Long COVID (LCov), two consecutive 450 s functional magnetic resonance imaging (fMRI) scans (Runs 1 and 2) were acquired on a 7 Tesla MRI...

Abstract: Persistent mitochondrial inflexibility and mitochondrial damage may contribute to Post-Acute Sequelae of COVID-19 (PASC). However, data linking mitochondrial biomarkers, such as circulating cell-free mitochondrial DNA (ccf-mtDNA) to long-COVID symptoms remain limited. We analyzed...

Phase I Open-Label Safety Trial of Pembrolizumab for Neurological Post- Acute Sequelae of SARS-CoV-2 (PD1-PASC I) Brief Summary Background: SARS-CoV-2 is the virus that causes COVID-19.Some people who recover from an acute COVID-19 infection may continue to have symptoms that persist for...

Abstract Background: Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) can develop as post-vaccination syndrome (PVS) or Post-Acute Sequelae of SARS-CoV-2 infection (PASC). In our prior retrospective study, most patients with PVS who developed ME/CFS had vitamin D insufficiency or...

Full title: Postural Orthostatic Tachycardia Syndrome, Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and Long COVID as Neuroimmune Disorders Abstract: Postural orthostatic tachycardia syndrome (POTS), myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and Long COVID are...

Diminished EBV-Specific Humoral Immunity is Associated with Neuropsychiatric Long COVID Development up to 12 Months Post-COVID-19 Symptom Onset [Line breaks added] Abstract Infection with SARS-CoV-2 can lead to long COVID, a chronic multisystemic condition estimated to affect approximately...

See post #5 for latest preprint version. Microvascular Remodeling and Endothelial Dysfunction Across Post-COVID-19 and ME/CFS: Insights from the All Eyes on PCS Study [Line breaks added] Background Post-viral diseases, including post-COVID-19 syndrome (PCS) and myalgic...

A cross-continental comparative analysis of the neurological manifestations of Long COVID [Line breaks added] Objective To compare demographics, comorbidities, neurologic symptoms, quality of life, and cognitive outcomes among adult individuals with neurologic manifestations of post-acute...

Identifying interventions and coping strategies to address the psychosocial repercussions of long-COVID: A qualitative interpretive meta-synthesis (QIMS) [Line breaks added] Abstract Long-COVID is a serious public health concern impacting millions of adults and children around the world...

Olfactory Dysfunction and Cognitive Deterioration in Long COVID: Pathomechanisms and Clinical Implications in Development of Alzheimer’s Disease Abstract Complete or partial loss of smell (anosmia), sometimes in association with distorted olfactory perceptions (parosmia), is a common...

Longitudinal Landscape of Long Flu and Long COVID Zheng, Ming [Line breaks added] Abstract Influenza is typically framed as an acute respiratory infection, yet accumulating evidence suggests that—like SARS-CoV-2—it may trigger persistent, multi-organ morbidity consistent with a post-acute...

Graph-Neural-Network-Based Brain Connectivity Analysis for Early Detection of Long-COVID Cognitive Impairments Using MRI/fMRI Dubey, Supriya; Singh, Jitendra; Bhardwaj, Manish [Line breaks added] Abstract Long-term COVID are frequently causing neurological problems that persist for long time...

Identifying potential post-COVID-19 condition among people experiencing homelessness using longitudinal symptom patterns: A prospective cohort study [Line breaks added] Objectives People experiencing homelessness have high SARS-CoV-2 infection and re-infection burden, potentially leading to...

Immunological Density Shapes Recovery Trajectories in Long COVID [Line breaks added] Abstract Post-acute sequelae of SARS-CoV-2 infection (Long COVID) frequently persists for months, yet drivers of clinical remission remain incompletely defined. Here we analyzed 97,564 longitudinal PASC...

Severe people may hold answers to Long COVID. They must be included in research. After giving several examples of research projects that have included more severe patients, they made these comments:

EEG-based frontal excitation/inhibition balance as an objective biomarker for cognitive fatigue across multiple sclerosis and Long COVID BACKGROUND Cognitive fatigue is a prevalent and disabling symptom in neurological and post-viral conditions, including multiple sclerosis (MS) and Long...

Trajectory, healthcare utilisation and recovery in 3590 individuals with long covid: a 4-year prospective cohort analysis BMJ Open: https://bmjopen.bmj.com/content/16/1/e103884 Abstract Objective To characterise long-term trajectory of recovery in individuals with long covid. Design...