long covid

Long-COVID: assessment of circulating markers suggests no cerebral neuronal damage, neuroinflammation or systemic inflammation–a controlled study An unedited version of the manuscript Background Long-COVID remains incompletely understood, particularly regarding the roles of peripheral...

Mesenchymal stromal cell therapy for post-COVID-19 syndrome: associated impact and mechanism Background Post-COVID-19 syndrome (PCS) affects around 10% of individuals who experience SARS-CoV-2 infection worldwide. This four-year follow-up study investigated the long-term impact of mesenchymal...

Association of symptoms of neuropsychological long COVID with imaging and plasma biomarkers Highlights • Neuropsychological long COVID i.e. “brain fog” were investigated by biomarkers. • Cognitive impairments related to abnormal rCBF in the occipital lobe. • Psychological symptoms related to...

Distinguishing post-COVID from long-COVID in adults: Development and validation of a biomarker signature using targeted proteomics and machine learning in a cross-sectional observational study Background COVID-19 can have diverse clinical manifestations, ranging from asymptomatic infection to...

Reclaiming health: a qualitative, explorative study of long covid recovery journeys involving mind-body approaches https://www.medrxiv.org/content/10.64898/2026.02.21.26345052v1 Objective This study explored the recovery experiences of individuals who report having (largely) recovered from...

Acute inflammation and fronto-striatal connectivity in the transition from acute to persistent fatigue after mild COVID-19: A longitudinal fMRI study Background Persistent fatigue is one of the most common and disabling sequelae of COVID-19, yet its neurobiological mechanisms remain poorly...

Paywall link: https://www.bostonglobe.com/2026/02/20/metro/long-covid-young-woman-treatment/ Archive link: https://archive.is/uJjel#selection-1173.0-1173.74

Abstract Post-acute sequelae of Covid-19 (PASC) refer to persistent symptoms lasting weeks to months after acute SARS-CoV-2 infection. However, identifying biological mechanisms, potential therapeutic targets, and modifiable environmental risk factors remains necessary. Here, we analyzed...

Full title: Prevalence of Circulating Autoantibodies Against G-Protein-Coupled Receptors as Potential Biomarkers for Long COVID: Preliminary Investigations Abstract This prospective, single-center, case-control study investigated circulating autoantibodies (AAbs) targeting G protein-coupled...

Emily Taylor, President and Chief Executive Officer of Solve M.E., discusses the significant socioeconomic burden of Long COVID, highlighting advances in research that can improve understanding of Long COVID and enable targeted interventions and better treatment protocols Long COVID is an...

Abstract: Cognitive dysfunction is a symptom of Long COVID. To characterize functional connectivity changes that may contribute to cognitive dysfunction in Long COVID (LCov), two consecutive 450 s functional magnetic resonance imaging (fMRI) scans (Runs 1 and 2) were acquired on a 7 Tesla MRI...

Abstract: Persistent mitochondrial inflexibility and mitochondrial damage may contribute to Post-Acute Sequelae of COVID-19 (PASC). However, data linking mitochondrial biomarkers, such as circulating cell-free mitochondrial DNA (ccf-mtDNA) to long-COVID symptoms remain limited. We analyzed...

Phase I Open-Label Safety Trial of Pembrolizumab for Neurological Post- Acute Sequelae of SARS-CoV-2 (PD1-PASC I) Brief Summary Background: SARS-CoV-2 is the virus that causes COVID-19.Some people who recover from an acute COVID-19 infection may continue to have symptoms that persist for...

Abstract Background: Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) can develop as post-vaccination syndrome (PVS) or Post-Acute Sequelae of SARS-CoV-2 infection (PASC). In our prior retrospective study, most patients with PVS who developed ME/CFS had vitamin D insufficiency or...

Full title: Postural Orthostatic Tachycardia Syndrome, Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and Long COVID as Neuroimmune Disorders Abstract: Postural orthostatic tachycardia syndrome (POTS), myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and Long COVID are...

Diminished EBV-Specific Humoral Immunity is Associated with Neuropsychiatric Long COVID Development up to 12 Months Post-COVID-19 Symptom Onset [Line breaks added] Abstract Infection with SARS-CoV-2 can lead to long COVID, a chronic multisystemic condition estimated to affect approximately...

See post #5 for latest preprint version. Microvascular Remodeling and Endothelial Dysfunction Across Post-COVID-19 and ME/CFS: Insights from the All Eyes on PCS Study [Line breaks added] Background Post-viral diseases, including post-COVID-19 syndrome (PCS) and myalgic...

A cross-continental comparative analysis of the neurological manifestations of Long COVID [Line breaks added] Objective To compare demographics, comorbidities, neurologic symptoms, quality of life, and cognitive outcomes among adult individuals with neurologic manifestations of post-acute...

Identifying interventions and coping strategies to address the psychosocial repercussions of long-COVID: A qualitative interpretive meta-synthesis (QIMS) [Line breaks added] Abstract Long-COVID is a serious public health concern impacting millions of adults and children around the world...

Olfactory Dysfunction and Cognitive Deterioration in Long COVID: Pathomechanisms and Clinical Implications in Development of Alzheimer’s Disease Abstract Complete or partial loss of smell (anosmia), sometimes in association with distorted olfactory perceptions (parosmia), is a common...