long covid

SON4PEM Study: Sonlicromanol in Post-COVID: A Randomized, Double-blind, Placebo-controlled, Phase II Trial Brief Summary The aim of this randomized, doube-blind, placebo-controlled, phase II trial, is to study the effect of sonlicromanol on fatigue in patiënt with post-COVID who experience...

Severe Neurocognitive Manifestations in Healthy Young Individuals With COVID-19: A Case Series Background A growing number of patients suffering from neurocognitive symptoms related to COVID-19 were observed as the pandemic progressed. This article addresses severe neurological manifestations...

Evidence of Impaired Neuroimmune System in Post‐COVID Syndrome—A Whole Brain Magnetic Resonance Spectroscopy Study [Line breaks added] Abstract Chronic fatigue, mood disturbances, and cognitive deficits characterize the neurological post‐COVID syndrome (PCS). This study aimed to find out if...

An article from The Sick Times explaining why telehealth (remote/virtual healthcare) is needed by patients with Long Covid, ME/CFS, and other chronic illness or disabilities. The article lists some actions that people in the USA and Canada can take to advocate for telehealth. Telehealth is...

Broadly neutralizing antibodies to SARS-CoV-2 in Long COVID are associated with viral persistence and clinical outcome Chenyu Liu, Daniel Sanson, Serhan Soylu, Leen Moens, Isabelle Meyts, Marc Jamoulle, Johan Van Weyenbergh [Line breaks added] Abstract Long COVID (also known as post-acute...

Desentangling the Long Covid biomarker network: Insights into viral persistence and therapeutic response using random forest feature selection Daniel Sanson , Chenyu Liu, Serhan Soylu, Leen Moens, Isabelle Meyts, Marc Jamoulle, Johan Van Weyenbergh [Line breaks added] Abstract Long COVID...

Exaggerated IFN-I Response in Long COVID PBMCs Following Exposure to Viral Mimics Purpose Long COVID (LC) is a long-term debilitating disease of which the exact pathophysiology is unknown. A dysregulated immune response resulting in hyperresponsive immune cells is hypothesized as a key...

Virtual Pet–Assisted Therapy to Alleviate Symptoms of Long COVID: A Prospective Pilot Interventional Study [Line breaks added] Background: Post–COVID-19 condition (long COVID) is characterized by persistent symptoms following acute infection. Given the limited efficacy of pharmacologic...

Case Report: Celiac plexus block improves gastrointestinal Long COVID symptoms Liu, Luke D.; Duricka, Deborah L. Abstract Lingering symptoms following SARS-CoV-2 infection, recognized as the clinical entity “Long COVID,” are common. Gastrointestinal dysfunction during and after COVID have...

From long COVID to neurodegeneration Carpio-Orantes, Luis Del No abstract. Snippets: Web | DOI | PMC | PDF | Brain Circulation | Commentary | Jan-Mar 2025

Risk Factors for Severe Post-COVID Condition in Children, Adolescents, and Young Adults [Line breaks added] Background Post-COVID condition (PCC) in children and young people (PCCcyp) remains a significant health burden. Early identification of patients at risk for severe disease, including...

The lingering shadow of epidemics: post-acute sequelae across history Miller, Christine M.; Moen, Janna K.; Iwasaki, Akiko Abstract The SARS-CoV-2 pandemic has drawn global attention to post-acute infection syndromes (PAIS), with millions affected by post-acute sequelae of COVID-19 (PASC, or...

Altered brain tissue microstructure and neurochemical profiles in long COVID and recovered COVID-19 individuals: A multimodal MRI study [Line breaks added] Background Diverse neurological symptoms are experienced by long COVID and COVID-19 recovered individuals. However, the long-term...

T cell-driven sustained inflammation and immune dysregulation mimicking immunosenescence for up to three years post-COVID-19 [Line breaks added] Abstract Long COVID has emerged as a major global health concern, yet the long-term trajectory of immune recovery and its contribution to...

Extracellular vesicles from long COVID patients promote RUNX2-mediated cellular stress via dysregulated miR-204 and p53 pathway activation [Line breaks added] Background: Subjects with Long COVID, also known as post-acute sequelae of SARS-CoV-2 infection (PASC)...

Autonomic dysfunction and vasoregulation in Long COVID-19 are linked to anti-GPCR autoantibodies [Line breaks added] Background SARS-CoV-2-triggered autoantibodies (AAB) targeting G protein-coupled receptors (GPCRs) have been suggested to contribute to the post-acute sequelae of COVID-19...

Effectiveness of inspiratory muscle training and multicomponent physical training in patients with post-COVID conditions: a systematic review and meta-analysis https://link.springer.com/article/10.1186/s13643-025-02982-1 BMC Systematic reviews Abstract Background There is evidence that fatigue...

Abstract: Long COVID, defined by symptoms persisting three months post-SARS-CoV-2 infection, presents a significant global health and economic challenge, with global prevalence estimated at 36% (ranging from 1–92%). This brief communication consolidates current knowledge on its economic...

A region-specific brain dysfunction underlies cognitive impairment in long COVID brain fog [Line breaks added] Abstract Long COVID "brain fog" is a common and debilitating subjective syndrome often associated with persistent cognitive impairment after COVID-19 infection. Here we identify a...

Association of Long COVID-Related inflammatory Processes in the Musculoskeletal System: 12-Month Longitudinal Cohort Feasibility Study Background A subset of individuals develops persistent symptoms following SARS-CoV-2 infection, including musculoskeletal (MSK) manifestations, a condition...