long covid

  1. Jesse

    Invivyd and Leading Researchers Form SPEAR Study Group to Assess the Effects of Monoclonal Antibody Therapy for Long COVID

    Key points: SPEAR Study Group initiated following multiple, independent reports of substantial clinical benefit associated with PEMGARDA® (pemivibart) therapy among people with Long COVID SPEAR Study Group collaborators Drs. Michael Peluso, Amy Proal, and David Putrino are key thought leaders...
  2. forestglip

    Trial Report REGAIN: A Randomized Controlled Clinical Trial of Oxaloacetate for Improving the Symptoms of Long COVID, 2025, Vernon et al

    REGAIN: A Randomized Controlled Clinical Trial of Oxaloacetate for Improving the Symptoms of Long COVID Suzanne D Vernon, Candace Rond, Jennifer Bell, Brindisi Butler, Sara Isolampi, Annaleah Otteson, Pearl Phalwane, Samantha Mower, Shad Roundy, David Kaufman, Alan Brian Cash, Lucinda Bateman...
  3. Sly Saint

    Lower Airway and Oral Microbiome Dysbiosis in Patients with Long COVID Post-Hospitalisation: A UK Multicentre, Prospective Cohort Study 2025

    Abstract Background: Acute COVID-19 alters the airway microbiota. Whether these changes persist post-COVID-19 and contribute to Long COVID (LC) is unknown. We aimed to describe the microbiota based on LC severity and subtype; and identify links with inflammation to find potential therapeutic...
  4. forestglip

    Hybrid Pulmonary Rehabilitation Improves Cardiorespiratory Exercise Fitness in Formerly Hospitalised Long COVID Patients, 2025, Chynkiamis et al

    Hybrid Pulmonary Rehabilitation Improves Cardiorespiratory Exercise Fitness in Formerly Hospitalised Long COVID Patients Nikolaos Chynkiamis, Angelos Vontetsianos, Christina Anagnostopoulou, Christiana Lekka, Maria Ioanna Gounaridi, Evangelos Oikonomou, Manolis Vavuranakis, Nikoleta Rovina...
  5. John Mac

    Immune Signatures in Post-Acute Sequelae of PASC and ME/CFS: Insights from the Fecal Microbiome and Serum Cytokine Profiles, 2025, Tobi et al

    Full title: Immune Signatures in Post-Acute Sequelae of COVID-19 (PASC) and Myalgia/Chronic Fatigue Syndrome (ME/CFS): Insights from the Fecal Microbiome and Serum Cytokine Profiles Abstract While there are many postulates for the etiology of post-viral chronic fatigue and other...
  6. rvallee

    Trial Report Awe reduces depressive symptoms and improves well-being in a randomized-controlled clinical trial, 2025, Lopez et al

    Awe reduces depressive symptoms and improves well-being in a randomized-controlled clinical trial https://www.nature.com/articles/s41598-025-96555-w Emerging evidence suggests that experiences of awe benefit health and well-being. The present investigation examined the efficacy of an awe...
  7. forestglip

    Preprint Integrative Bioinformatics Analysis Identifies Peripheral Blood Hub Genes and Establishes a Five-Gene Diagnostic Model for Long COVID, 2025, Liu et al

    Integrative Bioinformatics Analysis Identifies Peripheral Blood Hub Genes and Establishes a Five-Gene Diagnostic Model for Long COVID Yang Liu, Yuwei Shen, Peilian Cao, Yuqiang Qian, Yutong Chen, Daxing Jiang, Jianan Li [Line breaks added] Background Long COVID (LC) is a multisystem condition...
  8. forestglip

    Trial Report Effect of normobaric and hyperbaric hyperoxia treatment on symptoms and cognitive capacities in Long COVID patients: [placebo RCT], 2025, D’hoore+

    Effect of normobaric and hyperbaric hyperoxia treatment on symptoms and cognitive capacities in Long COVID patients: a randomised placebo-controlled, prospective, double-blind trial Leen D’hoore, Peter Germonpré, Bert Rinia, Leonard Caeyers, Nancy Stevens, Costantino Balestra [Line breaks...
  9. John Mac

    Preprint There Is No Established Connection Between Long-COVID and Chronic Fatigue Syndrome, 2025, Kouyoumdjian et al

    https://www.preprints.org/manuscript/202506.2016/v1 Abstract Fatigue is the most common symptom of Long-COVID (LC), characterized by persistent or new symptoms occurring at least three months after the initial SARS-CoV-2 infection, with no other identifiable cause. This study aims to assess the...
  10. ahimsa

    USA: News from Patient-Led Research Collaborative

    I wasn't sure where to put the news about this group's July 9 webinar. So I created a new thread for the Patient-Led Research Fund organization. Please move this post if it belongs elsewhere. Website for Patient-Led Research Collaborative Linktree for Patient-Led Research Collaborative...
  11. forestglip

    Dysregulated monocyte compartment in PACS patients, 2025, Kronstein-Wiedemann et al

    Dysregulated monocyte compartment in PACS patients Romy Kronstein-Wiedemann, Madeleine Teichert, Elisa Michel, Janina Berg, George Robinson, Kristin Tausche, Martin Kolditz, Johannes Bergleiter, Jessica Thiel, Dirk Koschel, Stephan R. Künzel, Kristina Hlig, Torsten Tonn, Manuela Rossol...
  12. forestglip

    [68Ga]FAPI PET/CT reveals increased pulmonary fibroblast activation protein expression in long COVID patients after ICU discharge, 2025, Leer et al

    [68Ga]FAPI PET/CT reveals increased pulmonary fibroblast activation protein expression in long COVID patients after ICU discharge B. van Leer, M. Londema, Ö. Kasalak, J. H. van Snick, M. L. Duiverman, J. C. Kuijvenhoven, M. D. de Kruif, D. E. Oprea-Lager, K. Pabst, M. E. Hellemons, H. H...
  13. forestglip

    Closed RECLAIM: Recovering From COVID-19 Lingering Symptoms Adaptive Integrative Medicine

    RECLAIM: Recovering From COVID-19 Lingering Symptoms Adaptive Integrative Medicine Drug: Ibudilast 10mg pills, 2 pills twice per day Other Names: Drug: Pentoxifylline 400mg pill 3 times per day Other: Placebo Placebo matching ibudilast, 2 pills twice per day OR placebo matching...
  14. forestglip

    P109 Circulating autoantibodies targeting G-protein-coupled neurotransmitter receptors: reliable biomarkers for long COVID diagnosis?, 2025, Camici+

    P109 Circulating autoantibodies targeting G-protein-coupled neurotransmitter receptors: reliable biomarkers for long COVID diagnosis? M Camici, M Franco, L Talamanca, E Cimini, E Tartaglia, S Notari, M Petino, L Scarnecchia, A Vergori, R Baldelli, P Zuppi, A Antinori [Line breaks added]...
  15. forestglip

    [Book chapter] How Stigma Emerges and Mutates: The Case of Long COVID Stigma, 2025, Farrimond et al

    8: How Stigma Emerges and Mutates: The Case of Long COVID Stigma Hannah Farrimond, Mike Michael [Line breaks added] Introduction How do new stigmas emerge? How do they relate to existing stigma? Why are we seeing an emergent devaluation and discrimination of people who have long COVID, given...
  16. ME/CFS Skeptic

    Phase 2b program with sonlicromanol in patients with mitochondrial disease due to m.3243A>G mutation, 2025, Smeitink et al.

    Abstract Mitochondrial disease incorporates a group of rare conditions with no approved treatment to date, except for Leber hereditary optic neuropathy. Therapeutic options to alleviate the symptoms of mitochondrial disease are urgently needed. Sonlicromanol is a promising candidate, as it...
  17. forestglip

    Still to open [Fort Lauderdale, Florida, USA] SARS-CoV-2 Specific Monoclonal Antibody for Post-COVID-19 Conditions (Long COVID)

    Effectiveness of Treating Post-COVID-19 Conditions (Long COVID) With the SARS-CoV-2 Specific Monoclonal Antibody, Sipavibart Brief Summary This placebo-controlled, randomized, blinded, two-arm phase II study will test the safety and potential efficacy of the targeted mAb, Sipavibart (formerly...
  18. forestglip

    Review Long-term neurological and cognitive impact of COVID-19: a systematic review and meta-analysis in over 4 million patients, 2025, Elboraay et al

    Long-term neurological and cognitive impact of COVID-19: a systematic review and meta-analysis in over 4 million patients Toka Elboraay, Mahmoud A. Ebada, Maged Elsayed, Heba Ahmed Aboeldahab, Hazem Mohamed Salamah, Omar Rageh, Mohamed Elmallahy, Hadeer Elsaeed AboElfarh, Lena Said Mansour...
  19. forestglip

    The pivotal role of central sensitization in long COVID, fibromyalgia and myalgic encephalomyelitis/chronic fatigue syndrome, 2025, Goldenberg

    The pivotal role of central sensitization in long COVID, fibromyalgia and myalgic encephalomyelitis/chronic fatigue syndrome Don L. Goldenberg Introduction Long COVID is a condition characterized by persistent unexplained symptoms following COVID-19 infection. These symptoms are not related to...
  20. forestglip

    [PASC] Across 12 Major Health Domains and 141 Diseases in Individuals With Mental Illness Among COVID-19 Survivors [...], 2025, Kang et al

    Postacute Sequelae of COVID-19 Across 12 Major Health Domains and 141 Diseases in Individuals With Mental Illness Among COVID-19 Survivors: A Population-Based Cohort Study in South Korea Jiseung Kang, Jaeyu Park, Yejun Son, Hyeon Jin Kim, Guillaume Fond, Laurent Boyer, Masoud Rahmati, Hayeon...
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