REGENECYTE cord blood cell therapy in post-COVID syndrome: a phase IIa randomized, placebo-controlled trial
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Background
Post-COVID syndrome affects a substantial proportion of individuals worldwide and imposes significant healthcare and economic burdens. Fatigue is one of...
Abstract:
Background
Post-COVID condition (PCCo) affects 5-10% of individuals following SARS-CoV-2 infection, with cognitive disturbances being a major feature. Central hypotheses regarding its pathophysiology include disturbed cell energy metabolism and oxidative stress pointing to...
Exhaled breath-based clusters in children with post-COVID condition
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Background:
Pediatric post-COVID condition (PPCC) presents as a heterogeneous disease with a broad spectrum of symptoms. This study aimed to identify distinct phenotypes of PPCC through an unbiased...
Long COVID Does Not Impair Hemodynamic, Vascular, or Autonomic Responses to Maximal Exercise: Sex-Stratified Study in Young Adults
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Background/Objectives: Long COVID (LC) has been linked to fatigue, exercise intolerance, and autonomic dysfunction, but sex-stratified data...
Long COVID in the context of driving styles: An empirical study employing connected vehicle trajectory data
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Abstract
This manuscript examines the "long-COVID" phenomenon, defined for this study as lasting changes in driving behavior stemming from pandemic-induced travel...
Choroid plexus alterations in long COVID and their associations with IL-6
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Abstract
SARS-CoV-2 disrupts the choroid plexus (ChP) epithelium by binding to the ACE-2 receptor, causing blood cerebrospinal fluid barrier leakage and permitting interleukin (IL)-6 and pathogens...
Journal of Clinical Medicine: Special Issue
Deadline for manuscript submissions: 20 January 2026
Special Issue Information
Dear Colleagues,
Postural orthostatic tachycardia syndrome (POTS), myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and long COVID are complex syndromes caused...
Percutaneous Auricular Nerve Stimulation for Treating Post-COVID Fatigue (PAuSing-pCF)
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Abstract
Even mild SARS-CoV-2 infection can lead to post-COVID syndrome, 70% of such patients have post-COVID fatigue (pCF).
Many physiological abnormalities observed in pCF could be...
“We need to be believed": A qualitative interview study on the Hertfordshire (UK) Long Covid and Physical Activity Study
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Background
The Covid-19 pandemic has led to the emergence of Long Covid, a complex multisystem condition characterised by persistent symptoms lasting...
Clinical Practice Guideline Recommendations for Post-Acute Sequelae of COVID-19
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Abstract
The guidelines presented herewith are based on the “Clinical Practice Guideline Recommendations for Post-Acute Sequelae of COVID-19 (PASC)” published in Infection & Chemotherapy in...
SGLT2 inhibitors prevent long-COVID-associated cognitive and pain symptoms in type 2 diabetes patients
Background
Long COVID presents significant health challenges, especially for patients with type 2 diabetes. Emerging evidence suggests that sodium-glucose cotransporter-2 (SGLT2) inhibitors...
Long-Term Health Effects of COVID-19 in Tunisia, 2020–2021
Background
Some patients suffer from persistent symptoms following a COVID-19 infection, referred to as long COVID. The aims of the study were to estimate the prevalence of long COVID and study its determinants in Tunisia.
Methods...
Impact of Micronutrients on Recovery and Rehabilitation Strategies in Long COVID
Saidov F.A.
Abstract
Long COVID, or post-acute COVID-19 syndrome, is characterized by persistent symptoms and functional impairment following acute SARS-CoV-2 infection. Micronutrients such as vitamins and trace...
An Interpretable Machine Learning Model for Predicting the Effectiveness of Low-Dose Methylprednisolone in Treating Long COVID: A Retrospective Study
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Abstract
Long COVID is a chronic, multisystem disease with limited response to conventional treatments. While low-dose...
Long COVID symptoms and loneliness: findings from the World Trade Center Health Registry
Sisti, Julia S.; Packard, Samuel E.; Metzler, Janna
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Background
Symptoms of long COVID can profoundly impact affected individuals’ functioning, including their ability to participate in...
Understanding how social determinants of health shape Long COVID outcomes: a rapid review of evidence
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Background
Long COVID affects over 65 million people worldwide, yet the impact of social determinants of health (SDoH), such as socioeconomic status, race/ethnicity...
Analysis of mucosal immune dysregulation and safety and tolerability of endoscopic topical steroid therapy for long-COVID hyposmia: randomized, double-blinded pilot study
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Background
Millions of people exhibit olfactory dysfunction years after acute SARS-CoV-2 infection...
Long COVID Prevalence and Risk Factors: A Systematic Review and Meta-Analysis of Prospective Cohort Studies
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Background: Long COVID, or post-acute sequelae of SARS-CoV-2 infection (PASC), affects millions globally, with persistent symptoms impacting quality of life. This...
Clinical Improvements Following a Non-Aerobic Therapeutic Exercise in Women with Long COVID
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Background/Objectives: Long COVID (LC) is characterized by persistent symptoms such as fatigue, pain, and reduced quality of life, often lasting months after acute infection...
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