long covid

“Long COVID”: The First Illness in History Named by Patients Mari Shiozaki Abstract The COVID‑19 pandemic created a large population of individuals who continued to experience debilitating symptoms long after the acute infection had resolved. This chapter examines the emergence of Long COVID...

Pathogen Effector Convergence Theory (PECT): A Protocol to Create a Unifying Framework for Post-Acute Infection Syndromes (PAISs) Jain, Nita Abstract Post-infectious syndromes (ME/CFS, Long COVID, PTLDS) represent significant global health challenges with overlapping clinical manifestations...

High prevalence of obstructive sleep apnea in patients with Long-COVID. Background Long-COVID (LC) is defined as the persistence of symptoms 12 weeks after the acute COVID infection not explained by any other alternative diagnosis. Its pathophysiology is poorly understood. Obstructive Sleep...

Sex Differences in Long COVID Prevalence Over One year After the Acute Phase, and Related Risk Factors. The GINA-COVID Cohort Study Background This 1-year cohort study aimed to track long COVID prevalence, identify associated risk factors, and assess its association with hospitalization...

Comparing ME/CFS following mononucleosis with Long COVID Jason, Leonard A; Furst, Jacob; Katz, Ben Z Objectives Long COVID following SARS-CoV-2 and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) following infectious mononucleosis (IM) are examples of post-infectious chronic...

Risk of Post-acute Symptoms and Conditions After SARS-CoV-2 Compared to Other Respiratory Viral Infections: A Systematic Review and Meta-Analysis Background How post-COVID-19 condition (PCC) differs from post-acute infection syndromes (PAIS) caused by other respiratory viruses remains...

Comprehensive Immunophenotyping of Monocytes and Dendritic Cells Suggests Distinct Pathophysiology in Chronic Fatigue Syndrome and Long COVID Abstract Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and long COVID are complex chronic conditions that often follow infectious...

Effects of Exercise-Based Pulmonary Rehabilitation in Patients with Long COVID: A Systematic Review and Meta-Analysis Background/Objective A substantial proportion of infected individuals develop persistent symptoms after the acute phase of COVID-19, regardless of initial disease severity...

Shear Stress Tolerance Threshold, eNOS Uncoupling, and the Two-Threshold Model of Post-Exertional Malaise in Long COVID: A Mechanistic Hypothesis with Implications for Physiotherapy Practice Karipidis, Yiannis K.; Karipidis, Konstantinos Y. Background A subset of Long COVID patients presents...

Aminopeptides ameliorate long COVID symptoms in immunocompromised rheumatic patients through immune reconstitution Objective To evaluate the effects of aminopeptide nutritional support on immune reconstitution and antiviral capacity in immunocompromised patients with rheumatic diseases...

Association of ADIPOQ rs1501299 with long-COVID syndrome: a single-center cross-sectional study Background Long-COVID syndrome is a public health issue, affecting millions of individuals worldwide. However, the pathophysiological mechanisms underlying the syndrome’s sequelae are still under...

The Long Tail of Long COVID-19: Broad and Extensive Increase in Utilization Within an Integrated Healthcare System https://www.cureus.com/articles/462075-the-long-tail-of-long-covid-19-broad-and-extensive-increase-in-utilization-within-an-integrated-healthcare-system Abstract Background The...

An imaging flow cytometry method to study platelet-monocyte aggregates using Long COVID as a model Background Long COVID is characterised by persistent systemic inflammation and endothelial dysfunction, with increasing evidence implicating thromboinflammatory mechanisms. Platelet-monocyte...

Microbiota-induced intestinal barrier disruption drives BAFF-mediated B-cell dysregulation and autoimmunity in long COVID Abstract Abstract Long COVID (post-coronavirus disease 2019 (COVID-19) condition) is an infection-associated chronic condition that can follow severe acute respiratory...

Whispers in the Dark: A Critical-Creative Exploration of Lived Experiences of Myalgic Encephalomyelitis (M.E) and Long Covid Based on a Collaborative Audiobook Listening Practice Jackson, Arlene Abstract This thesis is composed of two parts: a novel, Dear Listener, and a critical commentary...

Elevated blood viscosity is associated with dysautonomia in long COVID symptoms Background Long COVID is associated with elevated inflammatory and antibody levels. Elevated plasma proteins can increase blood viscosity and decrease blood flow. Our aim is to evaluate if blood viscosity is...

Exploring duplication in reviews of Long COVID: 2020-2023 Gary Austin Raine; Claire Loise Khouja Background The unnecessary duplication of reviews is a recognised problem in the field of evidence synthesis. This paper reports findings from a study exploring potential duplication of effort in...

Background Fatigue persists as a dominant and debilitating phenomenon in long-COVID, yet its underlying biological mechanisms remain unclear. While inflammatory variables tend to normalize within months post-infection, fatigue continues to significantly impact quality of life. Understanding...

Occurrence and persistence of symptoms, diagnoses and prescriptions after community-diagnosed COVID-19: a matched cohort study using the OpenSAFELY platform https://pubmed.ncbi.nlm.nih.gov/41887765/ Background: We aimed to explore the occurrence and persistence of symptoms...

MicroRNA sequencing of peripheral blood mononuclear cells reveals significant expression changes in women with Long COVID Abstract Long COVID is a clinical condition marked by persistent symptoms like fatigue and brain fog, estimated to have affected many of post-SARS-CoV-2/COVID-19...