long covid

Persistent Sleep Disturbance Following Pandemic Lockdowns: Longitudinal Findings From the UK COVID ‐19 Symptom Study Biobank ABSTRACT Sleep disturbance and fatigue were highly prevalent during the COVID-19 pandemic, in both infected and non-infected individuals, though mostly assessed...

Estimating the Quality-Adjusted Life-Year Loss due to Fatal and Nonfatal COVID-19 Outcomes across US States and Counties, July 2020 to December 2022 Abstract Objective: The population-level quality-of-life impact of nonfatal health outcomes, including prolonged hospitalizations and long...

Post‐Omicron cognitive decline is largely reversible: Two‐year multicenter cohort study of domain‐specific outcomes in hospitalized patients Abstract Background Cognitive impairment represents a significant concern within the spectrum of post-acute sequelae of Severe Acute Respiratory...

COVID-19 vaccination timing, relative to acute COVID-19, and subsequent risk of long COVID Summary Background Vaccination is a vital tool in preventing acute COVID-19 and may confer additional protection against Long COVID, although it is unclear whether this protection wanes over time...

IL-6 family cytokines behind acute COVID-19 and Long COVID syndrome: Mechanisms, biomarkers, and intervention strategies Bustos, Matilde; Rodríguez-Hernández, María Ángeles Highlights IL-6 family cytokines differentially contribute to COVID-19 and Long COVID. Biomarker strength differs among...

An exploratory exome-wide machine learning analysis identifies candidate host gene signatures associated with Long COVID in a large admixed Brazilian cohort Introduction Genetic factors have been suggested as modifiers of vulnerability to postCOVID-19 sequelae, referred to as Long COVID (LC)...

Item comprehension and content coverage of patient-reported outcome measures for long COVID: a qualitative study Abstract Purpose Fit-for-purpose clinical outcome assessments are essential to inform medical product development, but outcome measures for Long COVID, a new and devastating...

Necroptosis and Cellular Stress Characterize Immune and Endothelial Dysfunction in Long COVID Abstract Background Long COVID, or Post-Acute Sequelae of SARS-CoV-2 infection (PASC), affects a significant proportion of COVID-19 survivors and is associated with persistent fatigue, dysautonomia...

Persistent neurological and behavioral alterations after SARS-CoV-2 infection in an optimized K18-hACE2 mouse model Abstract Introduction: Persistent neurological symptoms are among the most prevalent and debilitating manifestations of post-COVID-19 Condition (PCC), affecting millions of...

Stress, social support, and long COVID diagnosis and symptom burden in women. Abstract Objectives: To examine whether general stress and childcare stress are associated with long COVID status, symptom number, and symptom duration in women, and whether perceived and received social support...

Efficacy of a psychotherapeutic group intervention for patients with Post-COVID-19 condition: a randomized controlled trial (PsyLoCo study) Abstract Background Persistent physical symptoms such as fatigue following SARS-CoV-2 infection are common and often accompanied by cognitive complaints...

https://clinicaltrials.gov/study/NCT05798221?id=NCT05798221&viewType=Card&rank=1&tab=study Complementary Self-help Strategies for Patients With Post-COVID-19 Syndrome (NASH-POCO) ClinicalTrials.gov ID: NCT05798221 Brief Summary Individuals affected by SARS-CoV-2 infection may subsequently be...

Background: Prior to the COVID-19 pandemic, the etiology of postural orthostatic tachycardia syndrome (POTS) remained elusive. Since the pandemic, a newly recognized disorder, termed Long COVID, has emerged with a significant subset of patients developing dysautonomia and a multitude of...

Evaluation of neuronal and immunological biomarkers in post-COVID-19 condition Highlights Plasma biomarkers reveal persistent inflammation in post-COVID condition (PCC) volunteers. Volunteers with neurological symptoms PCC-NS showed high IgA levels. PCC-NS volunteers presented elevated...

Systematic review of randomized clinical trials for the treatment of long COVID syndrome Background There is a critical need for interventions for long COVID. Our aim was to conduct a systematic review on the efficacy and safety of different interventions in patients with long COVID...

Neurologic Manifestations of Long COVID Affect Adult Females More Severely Than Males ABSTRACT Objective To characterize differences in neurologic manifestations of postacute sequelae of SARS-CoV-2 infection (Neuro-PASC) between females and males. Methods Cross-sectional study of the first...

Post-Acute Sequelae of COVID-19 Across 15 Major Health Domains and 67 Diseases in Individuals With Depressive Disorder: A Korean Nationwide Cohort Study Abstract Background Individuals with depressive disorder often face barriers in accessing healthcare; however, research on the acute and...

Ozone therapy by rectal insufflation in long COVID syndrome: a preliminary study with thermographic evaluation and quality of life measurement Abstract Introduction Post-acute coronavirus disease 2019 syndrome (PACS) is a multisystemic clinical condition that clinically starting weeks or...

At the Icahn School of Medicine at Mount Sinai, the neuroscientist and long COVID expert David Putrino is collecting blood samples from some of the patients who responded well to Vyvgart. He hopes the samples could enable better immune phenotyping so clinicians can predict whether a person with...

https://cen.acs.org/pharmaceuticals/drug-development/long-covid-pots-mecfs-drug-trials-ethics/104/web/2026/07 4000-word article. Access to potential long COVID drugs dwindles as trials falter Two sets of studies for COVID-driven conditions show the struggles of drug development by Rowan Walrath...