long covid

Chronic stress primes TLR3-mediated systemic inflammation to produce persistent post-viral fatigue syndrome-like symptoms in mice Highlights • Chronic stress in combination with poly I:C produces persistent multi-domain PVFS-like symptoms in mice. • Minocycline attenuates fatigue...

Implications of RNA virus persistence for post-acute sequelae and chronic inflammatory syndromes Vidal, Daniela; Castro, Ítalo de Araújo; López, Carolina B. Abstract Viral persistence refers to the ability of a virus to remain in its host for an extended period. Although most non-retroviral...

Long-term trajectories of social adjustment and emotional/behavioral problems in pediatric post-acute COVID-19 Abstract COVID-19 has been associated with adverse mental health outcomes in children. However, evidence regarding the long-term trajectories of post-acute symptoms remains limited...

Post-COVID-19 immune dysregulation and autoimmune sequelae Abdel-Moneim, Ahmed S.; Al-Balushi, Mohammad S.; Al-Jabri, Ali A. Highlights SARS-CoV-2 infection can induce persistent immune dysregulation : hyperinflammation, lymphopenia, and innate–adaptive imbalance. Molecular mimicry, bystander...

Dissociation Between Peripheral Muscle Strength and Exercise Capacity in Symptomatic Post‐COVID‐19 Individuals: Implications for Musculoskeletal Rehabilitation ABSTRACT Introduction Infection with SARS-CoV-2 may result in persistent functional impairment after the acute phase of the disease...

Association between corticosteroid therapy during acute COVID-19 and Long COVID symptoms: a propensity score overlap-weighted analysis Highlights • Long-term effects of acute-phase corticosteroids remain uncertain. • Overlap weighting was applied in a multicenter COVID-19 cohort. •...

Association of kynurenine metabolites with cognitive and psychological symptoms in post COVID-19 condition: A case-control study Background Cognitive dysfunction and psychological symptoms, including depression and anxiety, are commonly observed in chronic post COVID condition (PCC)...

Symptomatic hypermobility as a risk factor for Long COVID with high post-exertional symptom exacerbation: further analysis of data from a retrospective online survey of adults in the United States and United Kingdom Background In a retrospective online survey, we assessed the extent to which...

Influence of inflammatory and reninangiotensin system gene polymorphisms ACE2 rs2285666, IL1A rs1800587, and TNF rs1800629 on COVID-19 severity and the persistence of symptoms in the post-COVID-19 phase: a cross-sectional study Objective We evaluated the influence of single-nucleotide...

https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2851024 Key Points Question Does cognitive rehabilitation (CR) improve goal attainment, cognitive, and clinical outcomes in people with cognitive impairment as a part of long COVID? Findings In this randomized clinical trial of...

Genetic evidence that advanced COVID-19 accelerates longitudinal brain atrophy: A Mendelian randomization study Abstract Coronavirus disease 2019 (COVID-19) was reported to persist long-term in the brain and leave several long-term neurologic sequelae. However, the causal relationship between...

Post-COVID-19 diabetes outcomes Abstract Long-COVID-19 presentation has not been evaluated with proper depth in patients with diabetes (DM). This retrospective study evaluated 870 patients (320 DM, 550 non-DM) followed for up to 7.1 months post-hospitalization. Acute myocardial infarction...

SSRI/SNRI and long COVID in children and adolescents with neuropsychiatric conditions: a cohort study from the RECOVER Initiative Abstract Long COVID has been an important health concern in children and adolescents, yet factors associated with its development remain incompletely understood...

Sensibility of the Episodic Disability Questionnaire among adults living with Long COVID in Canada, Ireland, the United Kingdom, and the United States Abstract Background: Persons living with Long COVID experience a range of health-related challenges that may fluctuate over time, known as...

Dynamic changes in cardiac autonomic function persist in the post-acute phase after SARS-CoV-2 infection in a hamster model of COVID-19 Abstract Background Autonomic nervous system (ANS) dysfunction is a central feature of long COVID syndrome, yet little is known about how it develops during...

Spezialisierte kognitive Angebote bei Long-COVID-Symptomen nicht überlegen Hüll, Michael Abstract (Machine Translation) Question: Do cognitive training and rehabilitation strategies improve cognitive symptoms (such as memory problems, impaired concentration, “brain fog”) in Long COVID...

Abstract Background The mechanisms driving the broad spectrum of Long COVID symptoms—such as fatigue, brain fog, pain, and dysautonomia—remain uncertain. This study investigated central sensitization (CS) as a potential contributor to symptom burden in patients with Long COVID. We aimed to...

Community-delivered hyperbaric oxygen therapy for people affected by long COVID: a pilot study Abstract Long COVID is an umbrella term commonly used to describe a range of symptoms, such as chronic fatigue, ‘brain fog’ and breathlessness, that persist for at least 12 weeks after acute...

Algorithm dependence of patient phenotypes in Long COVID: a patient-led, multi-method clustering of 6031 patients using 162 self-reported symptoms Objectives Long COVID, characterized by symptoms that remain or emerge in the months after acute COVID-19 infection, is a multisystemic condition...

Effectiveness of adapted physical activity and therapeutic exercise programme in improving chronic fatigue syndrome in long COVID, delivered via hospital-based rehabilitation versus telerehabilitation Background Long COVID is a prevalent condition characterised by pain, fatigue, disability...