lupus

  1. Sly Saint

    Article: Simple blood test offers new hope to lupus patients

    Simple blood test offers new hope to lupus patients
  2. forestglip

    Review Ignored, Dismissed, and Minimized: Understanding the Harmful Consequences of Invalidation in Health Care [...], 2025, Bontempo et al

    Ignored, Dismissed, and Minimized: Understanding the Harmful Consequences of Invalidation in Health Care—A Systematic Meta-Synthesis of Qualitative Research Allyson C. Bontempo, John M. Bontempo, Paul R. Duberstein [Line breaks added] Abstract The upsurge in the prevalence of contested...
  3. H

    Is it useful to compare CBT in SLE and ME/CFS?

    I’ve been wondering whether it’s helpful to compare how cognitive behavioral therapy (CBT) is used in systemic lupus erythematosus (SLE) and in ME/CFS. Both are complex, multifactorial chronic illnesses. Adverse childhood experiences are also thought to increase the risk of developing SLE, and...
  4. forestglip

    Correlation of Interferons and Autoimmune Aspects in Long COVID-19 Patients, 2025, Hattori et al

    Correlation of Interferons and Autoimmune Aspects in Long COVID-19 Patients Fumiyuki Hattori, Junji Nishiyama, Hideaki Hasuo [Line break added] Abstract Long COVID, or post-acute sequelae of COVID-19 (PASC), represents a major global health challenge, with its underlying mechanisms remaining...
  5. forestglip

    Exploring the shared mechanism of fatigue between [lupus] and [ME/CFS]: monocytic dysregulation..., 2024, Zheng et al

    Exploring the shared mechanism of fatigue between systemic lupus erythematosus and myalgic encephalomyelitis/chronic fatigue syndrome: monocytic dysregulation and drug repurposing Daisi Zheng, Xiaolong Li, Qingmiao Zhu, Zhiyan Huang, Peicheng Wang, Ting Zhao [Provisionally accepted] Edit: Now...
  6. Joan Crawford

    Epstein–Barr virus as a potentiator of autoimmune diseases

    Epstein–Barr virus as a potentiator of autoimmune diseases William H. Robinson, Shady Younis, …Tobias V. Lanz Show authors Nature Reviews Rheumatology (2024)Cite this article Metricsdetails Abstract The Epstein–Barr virus (EBV) is epidemiologically associated with development of autoimmune...
  7. SNT Gatchaman

    Interferon gene expression declines over time post-COVID infection and in long COVID patients, 2024, Gómez-Carballa et al.

    Interferon gene expression declines over time post-COVID infection and in long COVID patients A. Gómez-Carballa; S. Pischedda; J. Pardo-Seco; J. Gómez-Rial; F. Martinón-Torres; A. Salas BACKGROUND Interferons (IFNs) represent a first-line defense against viruses and other pathogens. It has been...
  8. SNT Gatchaman

    Interferon subverts an AHR–JUN axis to promote CXCL13+ T cells in lupus, 2024, Law et al.

    Interferon subverts an AHR–JUN axis to promote CXCL13+ T cells in lupus Law, Calvin; Wacleche, Vanessa Sue; Cao, Ye; Pillai, Arundhati; Sowerby, John; Hancock, Brandon; Horisberger, Alice; Bracero, Sabrina; Skidanova, Viktoriya; Li, Zhihan; Adejoorin, Ifeoluwakiisi; Dillon, Eilish; Benque, Isaac...
  9. Sly Saint

    Drug used by millions for common condition could end pain for arthritis sufferers

    Researchers found medication that controls blood sugar levels in type 2 diabetes can also help patients with certain auto-immune diseases such as Lupus and arthritis Drug used by millions for common condition could end pain for arthritis sufferers - Mirror Online
  10. Andy

    Longitudinal gut microbiome analyses and blooms of pathogenic strains during lupus disease flares, 2023, Azzouz et al

    Objective Whereas genetic susceptibility for systemic lupus erythematosus (SLE) has been well explored, the triggers for clinical disease flares remain elusive. To investigate relationships between microbiota community resilience and disease activity, we performed the first longitudinal...
  11. Sly Saint

    Cochrane review: What are the benefits and risks of exercise for people with systemic lupus erythematosus?

    Published: 19 April 2023 Authors: Frade S, O'Neill S, Greene D, Nutter E, Cameron M https://www.cochrane.org/CD014816/MUSKEL_what-are-benefits-and-risks-exercise-people-systemic-lupus-erythematosus full review here...
  12. Sly Saint

    Fatigue is independently associated with disease activity assessed using the PGA but not the SLEDAI in systemic Lupus erythematosus, 2022, Mertz et al

    Fatigue is independently associated with disease activity assessed using the Physician Global Assessment but not the SLEDAI in patients with systemic lupus erythematosus Abstract Objectives To analyse whether reported fatigue, one of the most challenging manifestations of systemic lupus...
  13. T

    "Scientists hail autoimmune breakthrough" - the Guardian

    I don't know if this has been posted elsewhere but I thought it was very interesting. I wonder if something like this might end up being helpful for a subset of pwME... https://www.theguardian.com/science/2022/sep/15/scientists-hail-autoimmune-disease-therapy-breakthrough-car-t-cell-lupus "In...
  14. cassava7

    2022: a banner year for systematic lupus erythematosus?, Lancet Rheumatology editorial

    2022 has been an auspicious year for systemic lupus erythematosus (SLE). In February, the interferon receptor inhibitor anifrolumab became only the second targeted agent to be approved in Europe for treatment of SLE in more than six decades. A few months later, a 7-year-old Spanish girl who...
  15. MSEsperanza

    Fatigue, patient reported outcomes, and objective measurement of physical activity in systemic lupus erythematosus, 2016, Mahieu et al

    Mahieu MA, Ahn GE, Chmiel JS, Dunlop DD, Helenowski IB, Semanik P, Song J, Yount S, Chang RW, Ramsey-Goldman R. Fatigue, patient reported outcomes, and objective measurement of physical activity in systemic lupus erythematosus. Lupus. 2016 Oct;25(11):1190-9. doi: 10.1177/0961203316631632. Epub...
  16. S

    Antibodies against human endogenous retrovirus K102 envelope activate neutrophils in SLE, 2021, Tokuyama et al

    Antibodies against human endogenous retrovirus K102 envelope activate neutrophils in systemic lupus erythematosus Maria Tokuyama, Bronwyn M. Gunn, Arvind Venkataraman, Yong Kong, Insoo Kang, Tasfia Rakib, Michael J. Townsend, Karen H. Costenbader, Galit Alter and Akiko Iwasaki Journal of...
  17. Andy

    Lupus susceptibility gene Esrrg modulates regulatory T cells through mitochondrial metabolism, 2021, Li et al

    Abstract. Estrogen-related receptor gamma (Esrrg) is a murine lupus susceptibility gene associated with T cell activation. Here, we report that Esrrg controls regulatory T cells (Treg) through mitochondria homeostasis. Esrrg deficiency impaired the maintenance and function of Treg cells...
  18. S

    Targeting CD38 with Daratumumab in Refractory Systemic Lupus Erythematosus, 2020, Ostendorf et al.

    Summary Daratumumab, a human monoclonal antibody that targets CD38, depletes plasma cells and is approved for the treatment of multiple myeloma. Long-lived plasma cells are implicated in the pathogenesis of systemic lupus erythematosus because they secrete autoantibodies, but they are...
  19. J

    Kynurenine pathway is altered in patients with SLE and associated with severe fatigue, 2018, Akesson et al.

    https://lupus.bmj.com/content/5/1/e000254
  20. Andy

    Trial By Error: A Post About Lupus and MUS, Not COVID

    https://www.virology.ws/2020/04/08/trial-by-error-a-post-about-lupus-and-mus-not-covid/
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