lupus

Low dose IL-2 therapy restores regulatory T cells in patients with systemic lupus erythematosus in a dose-dependent manner: a phase IIb trial Abstract Low-dose interleukin 2 (Ld-IL2) has shown therapeutic effects in autoimmune diseases, particularly systemic lupus erythematosus (SLE), yet...

This is a poster I think, about a survey by Lupus Foundation of America. I don't find a full article anywhere. Authors: Daly R, Partovi R. Background/Purpose: Delays in lupus diagnosis and misdiagnosis are sources of concern, as uncontrolled disease activity and early damage can increase...

https://www.independent.co.uk/life-style/health-and-families/health-news/lupus-treatment-remission-cart-cell-therapy-nhs-b2994527.html

Editor’s Summary Epstein-Barr virus (EBV) has been making waves as a candidate driver of diseases like multiple sclerosis and Long Covid. It has also long been linked to systemic lupus erythematosus (SLE), although the “why” behind this link has not been defined. Here, Younis et al. provide...

https://medicalxpress.com/news/2025-10-car-nk-cells-evade-immune.html

Abstract A woman with aggressive refractory systemic lupus erythematosus was treated with a short course of the bispecific antibody teclistamab (anti–B-cell maturation antigen and anti-CD3) and had a drug-free complete remission. Link Full article if you follow the link in the comments (not...

Common Variants within MECP2 Confer Risk of Systemic Lupus Erythematosus Amr H. Sawalha; Ryan Webb; Shizhong Han; Jennifer A. Kelly; Kenneth M. Kaufman; Robert P. Kimberly; Marta E. Alarcón-Riquelme; Judith A. James; Timothy J. Vyse; Gary S. Gilkeson; Chan-Bum Choi; R. Hal Scofield; Sang-Cheol...

Variants within MECP2, a key transcription regulator, are associated with increased susceptibility to lupus and differential gene expression in patients with systemic lupus erythematosus Ryan Webb; Jonathan D. Wren; Matlock Jeffries; Jennifer A. Kelly; Kenneth M. Kaufman; Yuhong Tang; Mark...

Diagnostic overshadowing in systemic lupus erythematosus (SLE): A qualitative study Rupert Harwood, Chris Wincup, David D’Cruz, and Melanie Sloan [Line breaks added] Objectives SLE diagnostic journeys can be protracted, with negative impacts on long-term health. This study explored the role...

Posting several links exploring temporal dynamics between interferon, autoantibodies, and autoimmune diseases (primarily lupus). (Review) Emerging concepts of type I interferons in SLE pathogenesis and therapy Note: SLE = systemic lupus erythematosus Links to references are active in the...

Simple blood test offers new hope to lupus patients

Ignored, Dismissed, and Minimized: Understanding the Harmful Consequences of Invalidation in Health Care—A Systematic Meta-Synthesis of Qualitative Research Allyson C. Bontempo, John M. Bontempo, Paul R. Duberstein [Line breaks added] Abstract The upsurge in the prevalence of contested...

I’ve been wondering whether it’s helpful to compare how cognitive behavioral therapy (CBT) is used in systemic lupus erythematosus (SLE) and in ME/CFS. Both are complex, multifactorial chronic illnesses. Adverse childhood experiences are also thought to increase the risk of developing SLE, and...

Correlation of Interferons and Autoimmune Aspects in Long COVID-19 Patients Fumiyuki Hattori, Junji Nishiyama, Hideaki Hasuo [Line break added] Abstract Long COVID, or post-acute sequelae of COVID-19 (PASC), represents a major global health challenge, with its underlying mechanisms remaining...

Exploring the shared mechanism of fatigue between systemic lupus erythematosus and myalgic encephalomyelitis/chronic fatigue syndrome: monocytic dysregulation and drug repurposing Daisi Zheng, Xiaolong Li, Qingmiao Zhu, Zhiyan Huang, Peicheng Wang, Ting Zhao [Provisionally accepted] Edit: Now...

Epstein–Barr virus as a potentiator of autoimmune diseases William H. Robinson, Shady Younis, …Tobias V. Lanz Show authors Nature Reviews Rheumatology (2024)Cite this article Metricsdetails Abstract The Epstein–Barr virus (EBV) is epidemiologically associated with development of autoimmune...

Interferon gene expression declines over time post-COVID infection and in long COVID patients A. Gómez-Carballa; S. Pischedda; J. Pardo-Seco; J. Gómez-Rial; F. Martinón-Torres; A. Salas BACKGROUND Interferons (IFNs) represent a first-line defense against viruses and other pathogens. It has been...

Interferon subverts an AHR–JUN axis to promote CXCL13+ T cells in lupus Law, Calvin; Wacleche, Vanessa Sue; Cao, Ye; Pillai, Arundhati; Sowerby, John; Hancock, Brandon; Horisberger, Alice; Bracero, Sabrina; Skidanova, Viktoriya; Li, Zhihan; Adejoorin, Ifeoluwakiisi; Dillon, Eilish; Benque, Isaac...

Researchers found medication that controls blood sugar levels in type 2 diabetes can also help patients with certain auto-immune diseases such as Lupus and arthritis Drug used by millions for common condition could end pain for arthritis sufferers - Mirror Online

Objective Whereas genetic susceptibility for systemic lupus erythematosus (SLE) has been well explored, the triggers for clinical disease flares remain elusive. To investigate relationships between microbiota community resilience and disease activity, we performed the first longitudinal...