lupus

Abstract. Estrogen-related receptor gamma (Esrrg) is a murine lupus susceptibility gene associated with T cell activation. Here, we report that Esrrg controls regulatory T cells (Treg) through mitochondria homeostasis. Esrrg deficiency impaired the maintenance and function of Treg cells...

Summary Daratumumab, a human monoclonal antibody that targets CD38, depletes plasma cells and is approved for the treatment of multiple myeloma. Long-lived plasma cells are implicated in the pathogenesis of systemic lupus erythematosus because they secrete autoantibodies, but they are...

https://lupus.bmj.com/content/5/1/e000254

https://www.virology.ws/2020/04/08/trial-by-error-a-post-about-lupus-and-mus-not-covid/

Full title: Medically explained symptoms: A mixed methods study of diagnostic, symptom and support experiences of patients with lupus and related systemic autoimmune diseases Authors: Melanie Sloan et al. (UK universities) Link...

https://www.google.at/amp/s/m.jpost.com/Israel-News/Ben-Gurion-University-develops-miracle-molecule-for-fighting-Lupus-612163/amp

Paywall, https://www.sciencedirect.com/science/article/pii/S089684111930099X Sci hub, https://sci-hub.se/10.1016/j.jaut.2019.05.003

https://eurekalert.org/pub_releases/2019-02/nlh-lsl021319.php

Paywalled at https://www.sciencedirect.com/science/article/pii/S1931312818305912

This is the kind of article I hate. Trying to be sympathetic but perpetuating the psychological myth. https://www.thetimes.co.uk/article/kirsty-young-must-go-softer-on-herself-during-break-from-desert-island-discs-2pkjdbfbn Includes: I worry, though, that Young’s affliction is a form of...

https://www.lupus.org/general-news/entry/senate-committee-advances-funding-for-lupus-research

Not addressing the underlying cause of course but by reducing inflammation associated with autoimmune diseases such as rheumatoid arthritis or lupus. It's a little bit garbled but as far as I can tell baking soda appears to reduce inflammation by inducing the cholinergic anti-inflammatory...

The researchers looked at genetic and protein information from both healthy people and those with autoimmune conditions, using a newly developed technique. https://www.nih.gov/news-events/news-releases/epstein-barr-virus-protein-can-switch-risk-genes-autoimmune-diseases The paper...

Full paper (open access) here: http://stm.sciencemag.org/content/10/434/eaan2306 Journal summary: Write up in New Scientist here: https://www.newscientist.com/article/2165088-autoimmune-disorder-lupus-may-be-triggered-by-bodys-bacteria/

this might be slightly incoherent or too long due to brain not working. i have lung issues.(*) my doctor's initial idea was 7 days of prednisone to calm lungs down, plus an adrenaline inhaler. i was a little concerned, but only on the basis of anecdotal reports and general caution. for...