Post-COVID-19 ME/CFS: a case report of the treatment and recovery of a 17-year-old high-school student
Oka, Takakazu
Background
Evidence is accumulating that some patients infected with SARS-CoV-2 develop persistent fatigue and cognitive dysfunction that meets the diagnostic criteria for...
Effects of Tai Chi on fatigue and resting-state brain activity in chronic fatigue syndrome: a randomized controlled fMRI study
Wang, Bin; Zhang, Xiaodong
Background
Chronic fatigue syndrome (CFS) is a complex disorder characterized by persistent fatigue, sleep disturbance, and cognitive...
Impact of frailty phenotype on chronic disease accumulation and healthy life years lost: A multi-state analysis of the UK Biobank
Background
Frailty is a systemic vulnerability syndrome linked to adverse health outcomes, yet its role in shaping the dynamic trajectory from health through...
Registered interventional trials fail to cover patient-prioritised treatments in Post-COVID condition (PCC)
Purpose
Despite the substantial health and socioeconomic burden of Post-COVID condition (PCC), no disease-modifying therapy has been established, largely because of clinical...
Uncertainty-Driven Healthcare Epistemic Injustice: Evidence from Chronic Fatigue Syndrome
Hugh Robertson-Ritchie
Abstract
In this thesis, I critique inappropriate and unhelpful responses to radical epistemic uncertainties in medicine, which, I argue, significantly contribute to epistemic...
Long COVID, chronic fatigue syndrome, and chronic lyme disease as Post-acute Infection Syndromes (PAIS): a translational synthesis
Sewell, Patrick E.; Reddy, Rohan
Background
Post-acute infection syndromes (PAIS) comprise a heterogeneous group of chronic, multisystem conditions characterized...
Functional enrichment of immune targeted gut microbiota in post-infectious myalgic encephalomyelitis/chronic fatigue syndrome
Abstract
Post-infectious myalgic encephalomyelitis/chronic fatigue syndrome (PI-ME/CFS) is a debilitating condition characterized primarily by profound fatigue and...
The increase of alpha-melanocyte-stimulating hormone in the plasma of chronic fatigue syndrome patients
Background
Despite extensive research, no reliable biological marker for chronic fatigue syndrome (CFS) has yet been identified. However, hyperactivation of melanotrophs in the pituitary...
Plasma and cerebrospinal fluid monoamine metabolism in patients with chronic fatigue syndrome: Preliminary findings
Abstract
The syndrome of chronic fatigue, feverishness, diffuse pains, and other constitutional complaints, often precipitated by an acute infectious illness and aggravated by...
Association between myalgic encephalomyelitis/chronic fatigue syndrome and irritable bowel syndrome: a systematic review and meta-analysis
Rajabi, Natalie; Ramdass, Prakash V. A. K.
Background
Irritable bowel syndrome (IBS) and myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) are...
Compound Ciwujia Granules for chronic fatigue syndrome with syndrome of deficiency of both heart and spleen: a multicenter, randomized, double-blind, double-dummy, positive drug-controlled trial
Jun Ren, Xiao-Tian Zhang, Chao-Qun Xie, Shou-Jian Wang, Ling-Jun Kong, Jing-Hu Li, Liang-Ji Liu...
Hormonal Responses to Exercise in Chronic Fatigue Syndrome
Abstract
Chronic fatigue syndrome (CFS) is a debilitating disease characterized by severe, unexplained fatigue and postexertional exacerbation of symptoms. We examined basal endocrine function in a group of CFS patients and a...
Muscle Symptoms Define a Stable Physiological Dysregulation Cluster in ME/CFS: Sex- and Menopause-Related Differences in Symptom Expression
Habermann-Horstmeier, Lotte; Horstmeier, Lukas Maximilian
Background
Muscle-related symptoms are among the most disabling manifestations of myalgic...
High Dimensional Profiling of T cells in ME/CFS Uncovers Sex Specific Dysregulation
McNally, Claire; Davis, Mark; Wilhelmy, Julie; Grimson, Andrew; Hanson, Maureen
Introduction
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME) is a debilitating and poorly understood chronic disease. ME...
ME/CFS and the thalamus as a precision gate: what reversible thalamocortical connectivity reveals about central gain in post-infectious fatigue
Strube, Andreas
Abstract
Kim and colleagues report a finding that is easy to understate: thalamic hyperconnectivity with sensorimotor and...
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