Hormonal Responses to Exercise in Chronic Fatigue Syndrome
Abstract
Chronic fatigue syndrome (CFS) is a debilitating disease characterized by severe, unexplained fatigue and postexertional exacerbation of symptoms. We examined basal endocrine function in a group of CFS patients and a...
Muscle Symptoms Define a Stable Physiological Dysregulation Cluster in ME/CFS: Sex- and Menopause-Related Differences in Symptom Expression
Habermann-Horstmeier, Lotte; Horstmeier, Lukas Maximilian
Background
Muscle-related symptoms are among the most disabling manifestations of myalgic...
High Dimensional Profiling of T cells in ME/CFS Uncovers Sex Specific Dysregulation
McNally, Claire; Davis, Mark; Wilhelmy, Julie; Grimson, Andrew; Hanson, Maureen
Introduction
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME) is a debilitating and poorly understood chronic disease. ME...
ME/CFS and the thalamus as a precision gate: what reversible thalamocortical connectivity reveals about central gain in post-infectious fatigue
Strube, Andreas
Abstract
Kim and colleagues report a finding that is easy to understate: thalamic hyperconnectivity with sensorimotor and...
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) gene expression signatures for the identification of compounds targeting metabolism
Dehlia, Ankush; Alizada, Zahra; Guthridge, Mark Andrew
Background
Pathological fatigue is a debilitating symptom in a range of chronic illnesses...
Contrasting neuroendocrine responses in depression and chronic fatigue syndrome
Abstract
Hypothalamic-pituitary-adrenal (HPA) axis and central 5-HT function were compared in chronic fatigue syndrome (CFS), depression and healthy states. 10 patients with CFS and 15 patients with major...
Orthostatic intolerance with small heart and/or disequilibrium in patients with myalgic encephalomyelitis/chronic fatigue syndrome: clinical update and paradigm shift
Miwa, Kunihisa
Abstract
Orthostatic intolerance (OI) is characterized by the inability to maintain an upright posture without...
In the newest study by Wüst and colleagues, they have both a Long Covid and a pre pandemic ME/CFS group. Both groups fulfill CCC, so experience PEM.
My question: is there any research into severe Long Covid (e.g. at least 12 months and disabling) that does not also fulfill ME/CFS criteria?
I...
Hypothalamic Dysfunction and Neurotransmitter Abnormalities in the Postviral Fatigue Syndrome
Abdel Magid Osman Bakheit
Thesis supervisor: Peter O. Behan
A thesis submitted for the degree of Doctor of Medicine (MD) of the University of Glasgow
Final paragraph
In conclusion, the studies...
Pacing and energy management with digital tools for conditions with chronic fatigue: What we know so far in ME/CFS and Long COVID
There is no abstract, so instead this is the last section:
Bottom line
Pacing works best when it is personalised, conservative, and supported by timely feedback...
Brief Summary
Exercise is an important contributor to general health and is considered a potential remedy for chronic diseases. This is in strong contrast with the observation that in most myalgic encephalomyelitis (ME/CFS) patients exercise aggravates their symptoms.
Recently, post-exertional...
The role of disease history score in the association between depression history and current ME/CFS among US adults
Mao, Song; Wu, Liangxia
Objective
To explore the role of disease history score in the association between depression history and current myalgic encephalomyelitis/chronic fatigue...
For 15,000 Mainers with ME/CFS, the next step is in Congress’ hands
https://www.pressherald.com/2026/07/19/for-15000-mainers-with-me-cfs-the-next-step-is-in-congress-hands-opinion/
The author urges Congress to fund the ME/CFS Research Roadmap.
Dynamic activity - fatigue relationships in daily life in CFS/ME: insights from ecological momentary assessment
Background
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating condition characterized by persistent fatigue and post-exertional malaise (PEM), in which...
Cerebrospinal fluid opening pressure in relation to symptomatology and craniocervical anatomy in patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)
Caleb Jolley, Björn A Bragée, Lauri Sakari Soinne, Helena Huhmar, Hans Billing, Bo Christer Bertilson, Per Sjogren...
https://neurologistmom.substack.com/p/when-doctors-suspect-the-parent-instead
600-word article from a neurologist and carer of a daughter with ME/CFS.
From the end:
About the author:
Australian registry reports poor health and wellbeing in people living with ME/CFS
Eaton-Fitch, Natalie; Marshall-Gradisnik, Sonya
Introduction
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a debilitating condition hallmarked by post-exertional malaise accompanied by an array...
Supplement and Dietary Self-Management Strategies in Women with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Population-Based Survey
Background
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating multisystem disorder marked by profound fatigue, cognitive...
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