me/cfs

Spironolactone for ME/CFS in a Patient Homozygous for rs5522 (I180V): A Case Report Donnellan, Patricia Abstract Background: Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating condition with no consistently effective treatment. The mineralocorticoid receptor variant...

Paywall link: https://www.bostonglobe.com/2026/02/20/metro/long-covid-young-woman-treatment/ Archive link: https://archive.is/uJjel#selection-1173.0-1173.74

Emily Taylor, President and Chief Executive Officer of Solve M.E., discusses the significant socioeconomic burden of Long COVID, highlighting advances in research that can improve understanding of Long COVID and enable targeted interventions and better treatment protocols Long COVID is an...

Symptom Clusters in ME/CFS Reflect Distinct Neuroimmune and Autonomic Pathophysiological Mechanisms: A Translational Model Habermann-Horstmeier, Lotte; Horstmeier, Lukas Maximilian [Line breaks added] Background Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating...

Effect of Metabolic Modulation on a Post-acute COVID-19 Vaccination Syndrome (PACVS) Cohort (ViTAL-SCAN19) Brief Summary The goal of this clinical trial is to evaluate whether metabolic modulation with a combined nutraceutical product can improve symptoms and metabolic health in adults...

Abstract Background: Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) can develop as post-vaccination syndrome (PVS) or Post-Acute Sequelae of SARS-CoV-2 infection (PASC). In our prior retrospective study, most patients with PVS who developed ME/CFS had vitamin D insufficiency or...

Full title: Postural Orthostatic Tachycardia Syndrome, Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and Long COVID as Neuroimmune Disorders Abstract: Postural orthostatic tachycardia syndrome (POTS), myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and Long COVID are...

Outcomes of ME/CFS Following Infectious Mononucleosis: Seven-year Follow-up of a Prospective Study Leonard A. Jason, Jacob Furst, Rebecca Worth, Ben Katz [Line breaks added] Background Many individuals with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) report experiencing an...

See post #5 for latest preprint version. Microvascular Remodeling and Endothelial Dysfunction Across Post-COVID-19 and ME/CFS: Insights from the All Eyes on PCS Study [Line breaks added] Background Post-viral diseases, including post-COVID-19 syndrome (PCS) and myalgic...

Abstract Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and post-COVID-19 syndrome share a symptom profile, including severe fatigue, cognitive dysfunction, exertional intolerance, sleep disturbances, hypervigilance, and the paradoxical state of being “wired but tired.” A...

See here for the abstract and links to the 2025 ME/CFS paper: link See here for a link to a 2024 paper on covid-19 outcomes: link (Development and evaluation of blood-based prognostic biomarkers for COVID disease outcomes using EpiSwitch 3-dimensional genomic regulatory immune-genetic...

Severe people may hold answers to Long COVID. They must be included in research. After giving several examples of research projects that have included more severe patients, they made these comments:

Journal of Clinical Medicine: Special Issue Deadline for manuscript submissions: 20 January 2026 Special Issue Information Dear Colleagues, Postural orthostatic tachycardia syndrome (POTS), myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and long COVID are complex syndromes caused...

Evaluating working memory functioning in individuals with myalgic encephalomyelitis/chronic fatigue syndrome: a systematic review and meta-analysis Penson, Maddison; Kelly, Kate [Line breaks added] Abstract Individuals with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS)...

Hormonal alterations in adolescent chronic fatigue syndrome Aim The chronic fatigue syndrome is associated with alterations in the hypothalamus‐pituitary‐adrenal axis and cardiovascular autonomic nervous activity, suggesting a central dysregulation. This study explored differences among...

Down-regulation of renin–aldosterone and antidiuretic hormone systems in patients with myalgic encephalomyelitis/chronic fatigue syndrome Miwa, Kunihisa Background Central nervous system dysfunction associated with myalgic encephalomyelitis (ME) has been postulated as the cause of chronic...

Does Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) Represent a Poly-Herpesvirus Post-Virus Infectious Disease? Ariza, Maria Eugenia; Mena Palomo, Irene; Williams, Marshall V. [Line breaks added] Abstract Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a...

Blog post by Fred Rossi.

Distinct Symptom Clusters Reflect Pathophysiological Mechanisms in ME/CFS Habermann-Horstmeier, Lotte; Horstmeier, Lukas M. [Line breaks added] Introduction Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a severe multisystemic disease with a broad spectrum of symptoms. A...

Evaluation of an online patient education program for children and young people with ME/CFS and their parents within the BAYNET FOR MECFS Study Background: ME/CFS (Myalgic Encephalomyelitis/Chronic Fatigue Syndrome) poses challenges for affected children and...