me/cfs

iPSC-Derived Myogenic Progenitor Cells from People with ME/CFS Reveal Altered Genes and Pathways with Drug Repurposing Potential Nguyen, Dao Background Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating multisystem disorder characterised by profound fatigue...

Abstract: Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a chronic and debilitating disease characterized by post-exertional malaise, fatigue and pain. Yet, its underlying biological mechanisms remain poorly understood. Extracellular vesicles (EVs) are nanoparticles carrying...

Tryptophan Metabolism and Aryl‐Hydrocarbon Receptor Agonists in the Gut Microbiome of People With Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Abstract Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating chronic disease with unknown biological basis and no...

Gastrointestinal symptoms correlate with core clinical features and systemic inflammation in myalgic encephalomyelitis/chronic fatigue syndrome Background Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating multisystem illness marked by fatigue, cognitive impairment...

Effectiveness of adapted physical activity and therapeutic exercise programme in improving chronic fatigue syndrome in long COVID, delivered via hospital-based rehabilitation versus telerehabilitation Background Long COVID is a prevalent condition characterised by pain, fatigue, disability...

Self-management support needs for individuals with Myalgic Encephalomyelitis and their next of kin – a qualitative study Grønning, Kjersti; Lysfjord, Liv Eli; Røstad, Ann Katrin Hagen Background Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a complex, disabling condition...

Abstract: Background Various chronic health conditions are associated with household vulnerability to food insecurity. There is limited evidence regarding the prevalence of food insecurity or the experiences and challenges related to nutrition and food access among people living with Myalgic...

Stigmatisation in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) - a scoping review Patricia Vester, Stefanos Boudouroglou-Walter, Chantal Wieting, Jonas Schreyögg, Niklas Dammann, Annemarie Feißel, Katharina Piontek, Christine Blome Objective Myalgic Encephalomyelitis/Chronic...

Overcoming barriers in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome research: The CureME participatory model Ella Abken, Caroline Kingdon, Sarah Tyson Abstract Research into Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) presents unique challenges. These stem from the...

Full recovery is possible: how women recover from myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) outside formal clinical settings Harper, Julie Aims Latest UK guidance for myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) states there is no cure (NICE, 2021), leaving...

Two-timepoint multidomain follow-up of post-COVID condition and ME/CFS: overlapping autonomic, small-fiber, and cognitive changes Background Post-COVID condition (PCC) and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) show marked clinical overlap, suggesting a shared...

Raman Spectroscopy Combined with Machine Learning Reveals Myalgic Encephalomyelitis–Associated Biomolecular Signatures at Rest and After Standardized Stress Abstract Myalgic encephalomyelitis (ME) is characterized by profound fatigue, post-exertional malaise (PEM), and cognitive dysfunction...

Long-Term Follow-Up of Women with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS): A 16-Year Longitudinal Study Background and Objectives Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a complex disorder characterized by persistent or relapsing fatigue lasting at...

Benchmarking large language models for cell-free RNA diagnostic biomarker discovery Abstract Large language models can synthesize biomedical knowledge, parse vast amounts of data, and generate code, positioning them as promising tools for biomarker discovery from high-throughput omics data...

Significant aggravation of pre-existing myalgic encephalomyelitis/chronic fatigue syndrome following proton beam therapy for sphenoid wing meningioma: case report Fischer, Christian; Seidlitz, Annekatrin; Krause, Mechthild Background Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS)...

Exploratory dried blood spot metabolomics identifies pathway-level convergence with ME/CFS biology in a self-reported PEM-like fatigue phenotype Hauguel, Pierrick; Anctil, Nicolas; Noel, Louis-Philippe Background Plasma and serum metabolomic studies of myalgic encephalomyelitis / chronic...

Association between light exposure patterns and multidimensional health outcomes in individuals with myalgic encephalomyelitis/chronic fatigue syndrome: findings from a prospective cohort study Background Light is a major environmental factor regulating circadian rhythms, sleep-wake cycles...

Multimodal approach to identify neuropsychophysiological subgroups in myalgic encephalomyelitis/chronic fatigue syndrome and their relevance for rehabilitation: protocol for a mechanistic cross-sectional and longitudinal study Introduction Myalgic Encephalomyelitis (ME)/Chronic Fatigue...

Higher-order brain processes, rather than early processing, underlie sensory problems in ME/CFS: Evidence from ERPs Sanjay Kumar, Alfred Veldhuis, Farzaneh Yazdani Introduction Patients with Myalgic Encephalomyelitis (ME)/Chronic Fatigue Syndrome (CFS) experience significant sensory...

The expanding potential of low-dose naltrexone in clinical practice with a focus on long COVID Practice Points 1. Use of low-dose naltrexone, typically dosed between 3 and 5 mg, is increasing in clinical practice for indications such as fibromyalgia, chronic pain syndrome, and post-COVID...