neuroinflammation

Targeted metabolomics identifies accurate CSF metabolite biomarkers for the differentiation between COVID-19 with neurological involvement and CNS infections with neurotropic viral pathogens Neu, Frieder; Nay, Sandra; Schuchardt, Sven; Klawonn, Frank; Skripuletz, Thomas; Suehs, Kurt-Wolfram...

Endometriosis, Pain, and Related Psychological Disorders: Unveiling the Interplay among the Microbiome, Inflammation, and Oxidative Stress as a Common Thread Cuffaro, Francesca; Russo, Edda; Amedei, Amedeo Endometriosis (EM), a chronic condition in endometrial tissue outside the uterus, affects...

https://www.sciencedirect.com/science/article/abs/pii/S0166432824002018 Behavioural Brain Research Available online 9 May 2024, 115045 Research article Persistent fatigue in post-acute COVID syndrome is associated with altered T1 MRI texture in subcortical structures: a preliminary...

Mast cell activation triggered by SARS-CoV-2 causes inflammation in brain microvascular endothelial cells and microglia Wu, Meng-Li; Xie, Chengzuo; Li, Xin; Sun, Jing; Zhao, Jincun; Wang, Jian-Hua SARS-CoV-2-induced excessive inflammation in brain leads to damage of blood-brain barrier...

Brain temperature and free water increases after mild COVID-19 infection Sharma, Ayushe A.; Nenert, Rodolphe; Goodman, Adam M.; Szaflarski, Jerzy P. The pathophysiology underlying the post-acute sequelae of COVID-19 remains understudied and poorly understood, particularly in healthy adults with...

Abstract Sustained smouldering, or low-grade activation, of myeloid cells is a common hallmark of several chronic neurological diseases, including multiple sclerosis1. Distinct metabolic and mitochondrial features guide the activation and the diverse functional states of myeloid cells2...

Neurological involvement among non-hospitalized adolescents and young adults 6 months after acute COVID-19 Havdal, Lise Beier; Selvakumar, Joel; Lund Berven, Lise; Stiansen-Sonerud, Tonje; Zetterberg, Henrik; Blennow, Kaj; Holmøy, Trygve; Wyller, Vegard The post-COVID-19 condition (PCC) is...

Neuroinflammatory imaging markers in white matter: insights into the cerebral consequences of post-acute sequelae of COVID-19 PASC Sean Clouston; Chuan Huang; Jia Ying; Zennur Sekendiz; Minos Kritikos; Ashley Fontana; Lev Bangiyev; Benjamin Luft Symptoms of coronavirus disease 2019 (COVID-19)...

Effects of Low-Level Blast on Neurovascular Health and Cerebral Blood Flow: Current Findings and Future Opportunities in Neuroimaging Kilgore, Madison O.; Hubbard, W. Brad Low-level blast (LLB) exposure can lead to alterations in neurological health, cerebral vasculature, and cerebral blood...

Cortical GABA Levels Are Reduced in Post-Acute COVID-19 Syndrome Marinkovic, Ksenija; White, David R.; Alderson Myers, Austin; Parker, Katie S.; Arienzo, Donatello; Mason, Graeme F. After recovering from the acute COVID-19 illness, a substantial proportion of people continue experiencing...

Blood-brain barrier breakdown in COVID-19 ICU survivors: an MRI pilot study Wen Shi; Dengrong Jiang; Hannah Rando; Shivalika Khanduja; Zixuan Lin; Kaisha Hazel; George Pottanat; Ebony Jones; Cuimei Xu; Doris Lin; Sevil Yasar; Sung-Min Cho; Hanzhang Lu Objectives Coronavirus disease 2019...

Highlights Neuroinflammation is the most convincing hypothesis for ME/CFS pathophysiology, explaining its multifaceted symptoms and pathological features. Across various neuroimaging techniques, including MRI, MRS, PET, and EEG, the frontal cortex was the most frequently observed region. Our...

Quantitative susceptibility mapping at 7 Tesla in COVID-19: mechanistic and outcome associations Catarina Rua; Betty Raman; Christopher T Rodgers; Virginia F J Newcombe; Anne Manktelow; Doris A Chatfield; Stephen J Sawcer; Joanne G Outtrim; Victoria C Lupson; Emmanuel A Stamatakis; Guy B...

Single-cell transcriptomics of human traumatic brain injury reveals activation of endogenous retroviruses in oligodendroglia Raquel Garza; Yogita Sharma; Diahann A.M. Atacho; Arun Thiruvalluvan; Sami Abu Hamdeh; Marie E. Jönsson; Vivien Horvath; Anita Adami; Martin Ingelsson; Patric Jern; Molly...

Single-cell profiling identifies distinct hormonal, immunologic, and inflammatory signatures of endometriosis-constituting cells Sun Shin; Youn-Jee Chung; Seong Won Moon; Eun Ji Choi; Mee-Ran Kim; Yeun-Jun Chung; Sug Hyung Lee Endometriosis consists of ectopic endometrial epithelial cells...

Frataxin Deficiency Drives a Shift from Mitochondrial Metabolism to Glucose Catabolism, Triggering an Inflammatory Phenotype in Microglia Francesca Sciarretta; Fabio Zaccaria; Andrea Ninni; Veronica Ceci; Riccardo Turchi; Savina Apolloni; Valerio Chiurchiu; Marta Tiberi; Nadia D'Ambrosi; Silvia...

SARS-CoV-2 induces acute neurological signs while Calcitonin Gene-Related Peptide CGRP signaling blockade reduces interleukin 6 IL-6 release and weight loss in mouse models Shafaqat M Rahman; David W Buchholz; Brian Imbiakha; Mason C Jaeger; Justin Leach; Raven M Osborn; Ann O Birmingham...

Published version linked in this later post here Preprint Abstract The COVID-19 pandemic caused by SARS-CoV-2 has triggered a consequential public health crisis of post-acute sequelae of COVID-19 (PASC), sometimes referred to as long COVID. The mechanisms of the heterogeneous persistent...

COVID-19 Induces Neuroinflammation and Suppresses Peroxisomes in the Brain A. Roczkowsky; D. Limonta; J. P. Fernandes; W. G. Branton; M. Clarke; B. Hlavay; R. S. Noyce; J. T. Joseph; N. S. Ogando; S. K. Das; M. Elaish; N. Arbour; D. H. Evans; K. Langdon; T. C. Hobman; C. Power Objective...

Distinct molecular profiles of skull bone marrow in health and neurological disorders Zeynep Ilgin Kolabas; Louis B. Kuemmerle; Robert Perneczky; Benjamin Förstera; Selin Ulukaya; Mayar Ali; Saketh Kapoor; Laura M. Bartos; Maren Büttner; Ozum Sehnaz Caliskan; Zhouyi Rong; Hongcheng Mai; Luciano...