pem

  1. forestglip

    Postorgasmic Illness Syndrome: Insights from Recent Literature on a Rare but Fascinating Disorder, 2025, Wdowiak et al

    Postorgasmic Illness Syndrome: Insights from Recent Literature on a Rare but Fascinating Disorder Krystian Wdowiak, Agnieszka Maciocha & Julia Wąż [Line breaks added] Abstract Post-orgasmic illness syndrome (POIS) is a rare condition characterised by flu-like and allergic symptoms that...
  2. forestglip

    368 - Relation of Immune Profile to Exercise-Induced Pain and Fatigue in [ME/CFS] and Post-acute Sequelae of SARS-CoV-2 Infection, 2025, Berardi et al

    368 - Relation of Immune Profile to Exercise-Induced Pain and Fatigue in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and Post-acute Sequelae of SARS-CoV-2 Infection Giovanni Berardi, Adam Janowski, Samuel McNally, Gregorius Bernhard, Alpana Garg, Kathleen Sluka Abstract Individuals with...
  3. forestglip

    Thesis Cerebral hemodynamics to acute exercise in Veterans with Gulf War Illness, 2025, Branchaw

    Cerebral hemodynamics to acute exercise in Veterans with Gulf War Illness Grace E. Branchaw Committee Members: Dr. Dane Cook, Chair Dr. Jill Barnes Dr. Jee-Seon Kim [Line breaks added] Introduction Gulf War Illness (GWI) is a chronic multisymptom illness (CMI) affecting approximately one...
  4. forestglip

    Physical activity and sedentariness levels in patients with post-exertional malaise resulting from post-COVID-19 syndrome, 2025, Elkebir et al

    Physical activity and sedentariness levels in patients with post-exertional malaise resulting from post-COVID-19 syndrome Kamel-Eddine Elkebir, Jo-Anne Gilbert, Thiffya Arabi Kugathasan, Camille Cazeneuve, Florian Chouchou, Marie-Eve Mathieu Background Post-exertional malaise (PEM) is a...
  5. hotblack

    Physical Therapy Management of Postural Orthostatic Tachycardia Syndrome Using a Pacing-Forward Clinical Approach: A Case Report, 2025, Powers et al

    Physical Therapy Management of Postural Orthostatic Tachycardia Syndrome Using a Pacing-Forward Clinical Approach: A Case Report Powers CD, Miranda NA, Davenport TE Abstract Objective: Postural Orthostatic Tachycardia Syndrome (POTS) is a form of autonomic dysfunction that affects hemodynamic...
  6. jnmaciuch

    COX-1 inhibitors (NSAIDs/acetaminophen) before activity to prevent/lessen PEM

    Hi all, I saw some discussion of NSAIDs already here: https://www.s4me.info/threads/nsaids.6504/ I wanted to make another thread specifically to talk about the timing of when NSAIDs are taken, and if that has an effect on helping with symptoms. Added: I'm only discussing NSAIDs for my...
  7. Hutan

    Post-Exertional Malaise in Long COVID: Subjective Reporting Versus Objective Assessment, 2025, Stussman, Nath, Walitt et al

    https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2025.1534352/abstract Background: Post-exertional malaise (PEM) is a central feature of Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and has emerged as a prominent feature of Long COVID. The optimal clinical...
  8. forestglip

    Preprint Wearable heart rate variability monitoring identifies autonomic dysfunction and thresholds for post-exertional malaise in Long COVID, 2025, Ruijgt+

    Wearable heart rate variability monitoring identifies autonomic dysfunction and thresholds for post-exertional malaise in Long COVID Twan Ruijgt, Anouk Slaghekke, Anneke Ellens, Kasper Janssen, Rob CI Wust Objectives Patients with Long COVID experience disabling fatigue, autonomic dysfunction...
  9. Trish

    PEM: A thread for sharing your experience of post-exertional malaise

    Do you get delayed PEM that makes your ME/CFS more severe for a day or more, up to and including permanently? I have started this thread to focus entirely on each poster describing your own experience of PEM. My aim is that we avoid theorising about the underlying biology - keep the focus on...
  10. forestglip

    Review Prevalence and Impact of [PEM] on Recovery in Adults with Post COVID-19 Condition. A Systematic Review with Meta-Analysis, 2025, Pouliopoulou et al

    Prevalence and Impact of Post-Exertional Malaise on Recovery in Adults with Post COVID-19 Condition. A Systematic Review with Meta-Analysis Dimitra V Pouliopoulou, Myranda Hawthorne, Joy C MacDermid, Nicole Billias, Erin Miller, Kieran Quinn, Simon Décary, Fahad A. Razak, Angela Cheung, Panagis...
  11. John Mac

    Measuring Post-Exertional Malaise with DePaul Symptom Questionnaires: Challenges and Opportunities, 2025, Jason

    https://www.lidsen.com/journals/neurobiology/neurobiology-09-01-267 Abstract Following mental or physical exertion, patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) experience Post-Exertional Malaise (PEM). Although self-report questions represent less expensive and...
  12. SNT Gatchaman

    Exertional Exhaustion [PEM] Evaluated by the Effects of Exercise on [CSF] Metabolomics–Lipidomics and Serine Pathway in [ME/CFS], 2025, Baraniuk

    Exertional Exhaustion Post-Exertional Malaise, PEM Evaluated by the Effects of Exercise on Cerebrospinal Fluid Metabolomics–Lipidomics and Serine Pathway in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Baraniuk, James N. Post-exertional malaise (PEM) is a defining condition of myalgic...
  13. forestglip

    Assessing current PEM severity (whether one is in a crash)

    In the News From Germany thread, I posted about how I emailed a researcher about an upcoming study on sleep in ME/CFS. Snippet from my email: Snippet from Claudia Schilling's response: Does any metric exist for assessing whether one is in a crash at the moment, and/or how bad the crash is...
  14. PrairieLights

    PEM question

    I read in a thread that some people find 30 second burst of high energy exercise helpful. I hadn't heard of that idea before and decided, why not give it a try to see if I am one of those people. I'm not. Anyway, didn't give me too bad of PEM. Most of it reared yesterday, today it's mild...
  15. Yann04

    Beyond the Clinic: Virtual Care as the Future of Long COVID Rehabilitation, 2025, Anderson et Bauer

    Abstract: Background and Purpose: As a result of COVID-19 infection, millions of individuals are now affected by Long COVID, and this number continues to increase. These individuals experience a multitude of symptoms and limitations that make accessing conventional rehabilitative care...
  16. Yann04

    Thesis Bedside Monitoring of Mitochondrial Function in Post- COVID Patients, 2024, Behr

    (masters thesis) Background: Post-COVID (PC) is characterized by prolonged symptoms following a COVID-19 infection, with Post-Exertional Malaise (PEM) being a feature with a large negative impact on quality of life. Mitochondrial dysfunction has previously been related to PEM-related symtpoms...
  17. Yann04

    What would a good questionnaire for diagnosing PEM look like?

    The most popular questionnaire for PEM is the De-Paul Symptom Questionnaire, which, to be frank, is not the best, as it mostly focuses on fatigue after exertion and seems to flag an unlikely proportion of people with other illnesses having PEM. It seems there isn’t much competition. The FUNCAP...
  18. Kalliope

    Medscape: Post-Exertional Malaise in Fatiguing Diseases: What to Know to Avoid Harmful Exercise - by Miriam Tucker

    Quote: Identifying the phenomenon of post-exertional malaise (PEM) in patients with fatiguing conditions is critical because it necessitates a far more cautious approach to exercise, experts said. PEM is a defining feature of the condition myalgic encephalomyelitis/chronic fatigue syndrome...
  19. SNT Gatchaman

    Effects of a symptom-titrated exercise program on fatigue and quality of life in people with post-COVID condition, 2024, Barz+

    Effects of a symptom-titrated exercise program on fatigue and quality of life in people with post-COVID condition – a randomized controlled trial Barz, Andreas; Berger, Joshua; Speicher, Marco; Morsch, Arne; Wanjek, Markus; Rissland, Jürgen; Jäger, Johannes Fatigue is the most prevalent symptom...
  20. Yann04

    Delayed Cytotoxicity: A relation to ME/PEM?

    It seems cytotoxicity (the ability of a stressor to damage cells) can be a phenomenon that is delayed in comparison to the original stimulus. Ie. it seems depending on the immune or chemical leading to cytotoxicity it can occur instantaneously to a week after. [1] It seems also a well regarded...
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