sars-cov-2

  1. John Mac

    Preprint Relationship between acute SARS-CoV-2 viral clearance with Long COVID Symptoms: a cohort study, 2024, Herbert et al

    Abstract Introduction: The relationship between SARS-CoV-2 viral dynamics during acute infection and the development of long COVID is largely unknown. Methods: A total of 7361 asymptomatic community-dwelling people enrolled in the Test Us at Home parent study between October 2021 and February...
  2. John Mac

    Trial Report Pro Inflammatory Cytokines Profiles of Patients With Long COVID Differ Between Variant Epochs, Ganesh et al, 2024

    https://pubmed.ncbi.nlm.nih.gov/38808863/ Abstract Background: Over 30% of patients with COVID-19 have persistent symptoms that last beyond 30 days and referred to as Long COVID. Long COVID has been associated with a persistent elevation in peripheral cytokines including interleukin-6...
  3. ahimsa

    Scientific American: A Fight About Viruses in the Air Is Finally Over. Now It’s Time for Healthy Venting

    [I think this belongs here - please move if necessary] A Fight About Viruses in the Air Is Finally Over. Now It’s Time for Healthy Venting https://www.scientificamerican.com/article/a-fight-about-viruses-in-the-air-is-finally-over-now-its-time-for-healthy/
  4. SNT Gatchaman

    Preprint An amyloidogenic fragment of the SARS CoV-2 envelope protein promotes serum amyloid A misfolding and fibrillization, 2024, Nady et al.

    An amyloidogenic fragment of the SARS CoV-2 envelope protein promotes serum amyloid A misfolding and fibrillization Asal Nady; Sean E Reichheld; Simon Sharpe SARS CoV-2 infection can affect a surprising number of organs in the body and cause symptoms such as abnormal blood coagulation...
  5. SNT Gatchaman

    The S1 subunits of SARS variants differentially trigger IL-6 signaling in brain endothelial cells and impact on microglia activation, 2024, Stangis+

    The S1 subunits of SARS-CoV-2 variants differentially trigger the IL-6 signaling pathway in human brain endothelial cells and downstream impact on microglia activation Michael Stangis; Daniel Adesse; Bhavya Sharma; Eduardo Castro; Kush Kumar; Neil Kumar; Masha Minevich; Michal Toborek...
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    • blood brain barrier brain covid endothelial cells microglia microglial activation neurovascular unit sars-cov-2 spike protein stat
    • Replies: 0
    • Forum: Long Covid research
  6. ahimsa

    Scientific American: Rampant COVID Poses New Challenges in the Fifth Year of the Pandemic

    Rampant COVID Poses New Challenges in the Fifth Year of the Pandemic “We’re still in a pandemic,” says a lead COVID official with the World Health Organization https://www.scientificamerican.com/article/rampant-covid-poses-new-challenges-in-the-fifth-year-of-the-pandemic/ (some extra line...
  7. SNT Gatchaman

    Preprint Plasma proteomic evidence for increased Alzheimer's disease-related brain pathology after SARS-CoV-2 infection, 2024, Duff et al.

    Plasma proteomic evidence for increased Alzheimer's disease-related brain pathology after SARS-CoV-2 infection Eugene P Duff; Henrik Zetterberg; Amanda Heslegrave; Abbas Dehghan; Paul Elliott; Naomi Allen; Heiko Runz; Rhiannon Laban; Elena Veleva; Christopher D Whelan; Benjamin B Sun; Paul M...
  8. SNT Gatchaman

    Viral afterlife: SARS-CoV-2 as a reservoir of immunomimetic peptides that reassemble into proinflammatory supramolecular complexes, 2024, Zhang et al.

    Viral afterlife: SARS-CoV-2 as a reservoir of immunomimetic peptides that reassemble into proinflammatory supramolecular complexes Zhang, Yue; Bharathi, Vanthana; Dokoshi, Tatsuya; de Anda, Jaime; Ursery, Lauryn Tumey; Kulkarni, Nikhil N.; Nakamura, Yoshiyuki; Chen, Jonathan; Luo, Elizabeth W...
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    • amyloid antimicrobial peptides cathelicidin il-6 inflammation mmp-9 molecular mimicry pamps sars-cov-2 transcriptome
    • Replies: 12
    • Forum: Long Covid research
  9. rvallee

    Evolution of enhanced innate immune suppression by SARS-CoV-2 Omicron subvariants, 2024, Towers et al

    Evolution of enhanced innate immune suppression by SARS-CoV-2 Omicron subvariants Nature, open access: https://www.nature.com/articles/s41564-023-01588-4 Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) human adaptation resulted in distinct lineages with enhanced...
  10. SNT Gatchaman

    SARS-CoV-2 infection causes dopaminergic neuron senescence, 2024, Yang et al.

    SARS-CoV-2 infection causes dopaminergic neuron senescence Liuliu Yang; Tae Wan Kim; Yuling Han; Manoj S. Nair; Oliver Harschnitz; Jiajun Zhu; Pengfei Wang; So Yeon Koo; Lauretta A. Lacko; Vasuretha Chandar; Yaron Bram; Tuo Zhang; Wei Zhang; Feng He; Chendong Pan; Junjie Wu; Yaoxing Huang; Todd...
  11. C

    Lethal Infection of Human ACE2-Transgenic Mice Caused by SARS-CoV-2-1 related Pangolin Coronavirus: 2024, Lai et al

    Bio Rxiv Lethal Infection of Human ACE2-Transgenic Mice Caused by SARS-CoV-2-related Pangolin Coronavirus GX_P2V(short_3UTR) Lai Wei, Shuiqing Liu, Shanshan Lu, Shengdong Luo, Xiaoping An, Huahao Fan, Weiwei Chen, Erguang Li, Yigang Tong, ProfileLihua Song Abstract SARS-CoV-2-related...
  12. SNT Gatchaman

    Glymphatic system dysfunction in recovered patients with mild COVID-19: A DTI-ALPS study, 2023, Wu et al.

    Glymphatic system dysfunction in recovered patients with mild COVID-19: A DTI-ALPS study Lin Wu; Zhi Zhang; Xiao Liang; Yao Wang; Yuan Cao; Meng Li; Fuqing Zhou Central nervous sequelae are often reported in recovered patients with COVID-19. It is not clear whether recovered COVID-19 patients...
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    • cognitive dysfunction diffusion tensor imaging dti-alps glymphatic system long covid mri perivascular spaces sars-cov-2
    • Replies: 0
    • Forum: Long Covid research
  13. SNT Gatchaman

    The SARS-CoV-2 spike glycoprotein interacts with MAO-B and impairs mitochondrial energetics, 2023, Pileggi et al.

    The SARS-CoV-2 spike glycoprotein interacts with MAO-B and impairs mitochondrial energetics Pileggi; Parmar; Elkhatib; Stewart; Alecu; Côté; Bennett; Sandhu; Cuperlovic-Culf; Harper SARS-CoV-2 infection is associated with both acute and post-acute neurological symptoms. Emerging evidence...
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    • autophagy mitochondria mitophagy monoamine oxidase neurodegenerative disease parkinsons sars-cov-2 spike protein
    • Replies: 18
    • Forum: Long Covid research
  14. SNT Gatchaman

    Expression of SARS-CoV-2 Nonstructural Proteins 3 and 4 Can Tune the Unfolded Protein Response in Cell Culture, 2023, Davies et al.

    Expression of SARS-CoV-2 Nonstructural Proteins 3 and 4 Can Tune the Unfolded Protein Response in Cell Culture Jonathan P. Davies; Athira Sivadas; Katherine R. Keller; Brynn K. Roman; Richard J.H. Wojcikiewicz; Lars Plate Coronaviruses (CoV), including SARS-CoV-2, modulate host proteostasis...
  15. SNT Gatchaman

    Repeated Omicron exposures override ancestral SARS-CoV-2 immune imprinting, 2023, Yisimayi et al.

    Repeated Omicron exposures override ancestral SARS-CoV-2 immune imprinting Yisimayi, Ayijiang; Song, Weiliang; Wang, Jing; Jian, Fanchong; Yu, Yuanling; Chen, Xiaosu; Xu, Yanli; Yang, Sijie; Niu, Xiao; Xiao, Tianhe; Wang, Jing; Zhao, Lijuan; Sun, Haiyan; An, Ran; Zhang, Na; Wang, Yao; Wang...
  16. SNT Gatchaman

    Dynamic label-free analysis of SARS-CoV-2 infection reveals virus-induced subcellular remodeling, 2023, Saunders et al.

    Dynamic label-free analysis of SARS-CoV-2 infection reveals virus-induced subcellular remodeling Nell Saunders; Blandine Monel; Nadege Cayet; Lorenzo Archetti; Hugo Moreno; Alexandre Jeanne; Agathe Marguier; Timothy Wai; Olivier Schwartz; Mathieu Frechin Assessing the impact of SARS-CoV-2 on...
  17. SNT Gatchaman

    [Preprint] Evolutionary arms race between SARS-CoV-2 and interferon signaling via dynamic interaction with autophagy, 2023, Lee et al.

    Evolutionary arms race between SARS-CoV-2 and interferon signaling via dynamic interaction with autophagy Jae Seung Lee; Mark Dittmar; Jesse Miller; Minghua Li; Kasirajan Ayyanathan; Max B Ferretti; Jesse Hulahan; Kanupriya Whig; Zienab Etwebi; Trevor Griesman; David C. Schultz; Sara Cherry...
  18. SNT Gatchaman

    Understanding COVID-19 progression with longitudinal peripheral blood mononuclear cell proteomics, 2023, Leite et al.

    Understanding COVID-19 progression with longitudinal peripheral blood mononuclear cell proteomics: Changes in the cellular proteome over time Giuseppe Gianini Figueirêdo Leite; Milena Karina Colo Brunialti; Paula M. Peçanha-Pietrobom; Paulo R. Abrão Ferreira; Jaquelina Sonoe Ota-Arakaki; Edecio...
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    • covid 19 fatty acid metabolism glycolysis mitochondria neutrophil extracellular traps neutrophils oxphos pbmc pentose phospate pathway proteomics sars-cov-2
    • Replies: 1
    • Forum: Long Covid research
  19. SNT Gatchaman

    Preprint Plasma-based antigen persistence in the post-acute phase of SARS-CoV-2 infection, 2023, Peluso, Swank et al.

    Plasma-based antigen persistence in the post-acute phase of SARS-CoV-2 infection Michael J. Peluso; Zoe N. Swank; Sarah A. Goldberg; Scott Lu; Thomas Dalhuisen; Ella Borberg; Yasmeen Senussi; Michael A. Luna; Celina Chang Song; Alexus Clark; Andhy Zamora; Megan Lew; Badri Viswanathan; Beatrice...
  20. SNT Gatchaman

    [Preprint] ... Multi-omics study identifies immune programs associated with COVID-19 severity and mortality in hospitalized participants, 2023

    Integrated longitudinal multi-omics study identifies immune programs associated with COVID-19 severity and mortality in 1152 hospitalized participants Jeremy P. Gygi; Cole Maguire; Ravi K. Patel; Pramod Shinde; Anna Konstorum; Casey P. Shannon; Leqi Xu; Annmarie Hoch; Naresh Jayavelu; IMPACC...
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