treatment

Abstract Objectives: Central sensitivity syndrome disorders such as fibromyalgia, provoke continued debate, highlighting diagnostic and therapeutic uncertainty. The Hyland model provides a way of understanding and treating the medically unexplained symptoms of central sensitivity syndromes...

https://erj.ersjournals.com/content/62/suppl_67/PA4639 Exercise capacity in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) treated with long-term pyridostigmine Johanna Squires, Sarra Al-Zayer, David Systrom European Respiratory Journal 2023 62: PA4639; DOI...

A team in Germany is planning to launch a trial with the drug IMU-838 trial for Long Covid. Currently there aren’t too many details on the trial, however Maria Vehreschild of the Universitätsklinikum Frankfurt has given some details in this talk www.vimeo.com/873993707/description (from 32:30...

Epstein-Barr virus-acquired immunodeficiency in myalgic encephalomyelitis-Is it present in long COVID? Abstract Both myalgic encephalomyelitis or chronic fatigue syndrome (ME/CFS) and long COVID (LC) are characterized by similar immunological alterations, persistence of chronic viral infection...

[Approx 25% of participants had LC] Background Chronic fatigue (CF) is a complex phenomenon without clear etiology that may require long-term treatment, but to date, no specific therapy has been identified for it. Some botanicals might be helpful in the management of CF. Among these botanicals...

'Many patients with neurogenic orthostatic hypotension also have hypertension in the supine position. The BP can be extremely labile, resembling a volatile stock market chart.' Abstract Symptoms of autonomic dysfunction are prevalent and can be very debilitating, reducing the quality of life...

Full title: Semi-supervised exercise training program more effective for individuals with postural orthostatic tachycardia syndrome in randomized controlled trial Abstract Purpose Exercise like any medication requires the correct dose; to be effective the appropriate frequency, duration, and...

https://direct.mit.edu/neco/article-abstract/26/11/2594/7999/Coenzyme-Q10-Benefits-Symptoms-in-Gulf-War?redirectedFrom=fulltext paywall I think Abstract We sought to assess whether coenzyme Q10 (CoQ10) benefits the chronic multisymptom problems that affect one-quarter to one-third of 1990–1...

The Role of Hypothalamic Phospholipid Liposomes in the Supportive Therapy of Some Manifestations of Long Covid: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and Brain Fog Abstract Long Covid is a heterogeneous clinical condition in which Myalgic Encephalomyelitis/Chronic...

Why telling pwOI to just drink more water might not be as helpful as you'd think. I feel this Instagram post is worth a read, including the comments.

Abstract Post-infectious fatigue is a common complication that can lead to decreased physical efficiency, depression, and impaired quality of life. Dysbiosis of the gut microbiota has been proposed as a contributing factor, as the gut–brain axis plays an important role in regulating physical...

Abstract Purpose Orthostatic intolerance commonly occurs following immobilization or space flight. We hypothesized that daily artificial gravity training through short-arm centrifugation could help to maintain orthostatic tolerance following head-down tilt bedrest, which is an established...

https://classic.clinicaltrials.gov/ct2/show/NCT05643794?recrs=abdf&type=Intr&cond=Fibromyalgia&draw=3&rank=11 Someone is moving ahead with the theory of autoimmune antibodies for fibromyalgia

Abstract Osteoarthritis (OA), the most common form of arthritis, is a significant public health burden in U.S. adults. Among its many risk factors, obesity is a key player, causing inflammation, pain, impaired joint function, and reduced quality of life. Dietary polyphenols and other bioactive...

The actual study start date was March 2023, the estimated primary end date was 1 June 2023 and the estimated study completion date is 1 October 2023. Clinical Trials link: https://clinicaltrials.gov/ct2/show/NCT05813587?term=Meplazumab&draw=2&rank=8 Randomized, double-blind...

The sequela of COVID-19 include a broad spectrum of symptoms that fall under the umbrella term post-COVID-19 condition or syndrome (PCS). Immune dysregulation, autoimmunity, endothelial dysfunction, viral persistence, and viral reactivation have been identified as potential mechanisms. However...

The effect of hyperbaric oxygen therapy on myocardial function in post-COVID-19 syndrome patients: a randomized controlled trial Leitman, Marina; Fuchs, Shmuel; Tyomkin, Vladimir; Hadanny, Amir; Zilberman-Itskovich, Shani; Efrati, Shai Post-COVID-19 condition refers to a range of persisting...

Post copied from the LC in the media thread

https://www.cochrane.org/CD014682/SYMPT_how-effective-are-antidepressants-used-treat-chronic-pain-and-do-they-cause-unwanted-effects Key messages • We are only confident in the effectiveness of one antidepressant: duloxetine. We found that a standard dose (60 mg) was effective, and that there...

Comparative Cohort Study of Post-Acute Covid-19 Infection with a Nested, Randomized Controlled Trial of Ivabradine for Those With Postural Orthostatic Tachycardia Syndrome (The COVIVA Study) David Saunders; Thomas B Arnold; Jason M Lavendar; Daoqin Bi; Karl Alcover; Lydia D Hellwig; Sahar T...