Aripiprazole - Abilify

Are there any planned / ongoing LDAbilify studies that have a control group?

A lot of people have reported positive effects, it seems worth investigating.

 

Ron Davis estimated that it would cost about $10 million dollars to do a full blown phase 3 trial. There is a FB group with about 5K members that you could join for more info.

 

Anyone have any idea what happens when ability “poops out”.

a gentle return to baseline?, permanent worsening? Temporary withdrawal?

ivd seen more good reports on social media on this drug than any other over the past 20 years so I got curious

 

I had withdrawals but others did not.

 

I haven't gone through all the messages but how does a doctor determine whether a pwME is a good candidate for this medication?

 

Yeah I’ve seen that group but I’m really skeptical of trying a drug that has a large number of people saying the drug made them worse over a long period. So I’m waiting for a properly controlled study until I consider.

 

I wanted to record that for the last 6 weeks I have been on a very low dose of aripiprazole. I started very low at .1 increasing by .1 a week so I am now on .6. I need to stop for other reasons but hope to restart after a short break. This is an extremely low dose so it may be unrealistic to expect any effects.

There have been no negative side effects except possibly a transient headache and maybe worsening sleep. Positive effects are also difficult to estimate. The one I consider definite is a relief from the fatigue/ hangover feeling on waking in the morning. This was a severe symptom with me, awful every day, I couldn't move until lunchtime but now, I wake about 9 ish and immediately go downstairs in my dressing gown. I don't attempt to go out but on the day I had a medical appointment in the morning, it was easier to manage. I have tried staying in bed for extra rest but I really can't.
Can I do more of other things? It is impossible to tell. I have had one severe crash which lost me the followIng several days after exceeding my energy envelope, otherwise I have led my very quiet life. Brain fog is still there. But then I am still on a very low dose. Will update when I can.

I am hoping I can use the break to help me 1. clarify whether my sleep improves as the aripiprazole leaves my system, and 2. whether I can wake up and move downstairs straightaway or whether the dreadful morning fatigue returns.

edit: I'm not part of a trial
edit2: on reading back through posts, there are other people for whom arip caused improvement in sleep at first but it didn't last which is my experience currently