Cognitive Rehabilitation and Functional Outcomes in Long COVID–Related Cognitive Impairment – A Randomized Clinical Trial, 2026, Vanova et al.

They managed to get into the German Ärzteblatt. Lots of doctors are going to see this.

Machine Translation of what I was able to access:
Long COVID and cognitive deficits: Patients benefit from individualized rehabilitation

Friday, 3 July 2026

London – People suffering from Long-COVID–related cognitive impairments appear to benefit from individualized cognitive rehabilitation. Researchers led by Martina Vanova at University College London report in JAMA Network Open that the rehabilitation helped affected individuals better achieve personally set goals than standard long-COVID care (2026; DOI: 10.1001/jamanetworkopen.2026.20687).

The findings are clinically meaningful, the authors say: on the one hand given the high prevalence of cognitive impairments in people with Long COVID, and on the other because of their impact on quality of life and everyday functioning.

Is there anything we can learn from this for the upcoming DecodeME & SequenceME papers?
 
Merged thread

Article in the Mirror newspaper

The first effective Long Covid brain rehab programme has been developed by UK scientists.

The team developed techniques which slashed symptoms, such as brain fog, and enabled patients to return to work and hobbies. Simple practices were coached to participants in a ten-week course of hour-long one-to-one video calls with a therapist.
The trial of 78 Long Covid patients by University College London is the first to show cognitive rehabilitation of Long Covid is possible. The study offers hope to thousands of families whose loved ones have been left effectively disabled by lasting symptoms of Covid-19.

Lead author Dr Martina Vanova said: “As many as one in three people with Covid go on to develop Long Covid, and cognitive difficulties are among the most common symptoms that can persist for months, disrupting day-to-day functioning and quality of life.
The pioneering programme, funded by the National Institute for Health and Care Research, helped sufferers improve working memory and maintain concentration. Long Covid patients often forget what they are doing and report not being able to sustain a conversation because they lose their train of thought.
Study participant Emma Sullivan, a mother of two from Surrey, caught Covid-19 in August 2021 and four months later was diagnosed with Long Covid.

Emma, 57, said: “It was terrible, affecting my life in lots of ways, but particularly mentally. I could no longer concentrate or multi-task and struggled with reading problems, exhaustion and speaking in full sentences.

“The sessions in the trial were really helpful, as they taught me to break tasks down into smaller pieces and stop getting so overwhelmed, and to visualise words that I couldn’t find.

“I built up my concentration abilities once again so I can finish a 1,000 piece jigsaw puzzle by myself, after previously struggling with my granddaughter’s 30-piece puzzles. I can now accept that long Covid has changed my life because now I can manage it better, therefore I’m living better.”
 
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