Dr Byron Hyde - Canada

So sorry for your loss.

 

Yes, I have read her response to that. A part of it may have been the freezing of samples. I'm shocked at how few patients were involved too. I had hoped ME Research UK could have funded a larger group

 

Still nothing public from Byron Hyde?

 

Merged thread

Byron Hyde "Understanding Myalgic Encephalomyelitis - The new polio and chronic fatigue syndromes" (Book)

Continues at:
https://25megroup.org/book-reviews

 

Dr Byron Hyde surrenders his medical license (S4ME thread, August 2019):
https://www.s4me.info/threads/dr-byron-hyde-surrenders-his-medical-license.10892/

 

Oh, how wonderful it must be to have such absolute certainty.

 

Merged thread

ME/CFS Alert with Llewellyn King and Deborah Waroff - Episode 121: Interview with Dr. Byron Hyde of the Nightingale Research Foundation

In this interview Dr. Byron Hyde, founder of the Nightingale Research Foundation in Ottawa, Canada, emphasizes the brain and enteroviruses. He also emphasizes his belief that Myalgic Encephalomyelitis and Chronic Fatigue Syndrome are separate issues.

https://www.youtube.com/watch?v=6sq95x-qBA4

 

"most physicians thought infectious disease was something that wasn't rational" -- at about 5 mins.

 

It's a pity that all the new research funding for corona virus will be of no benefit to us if ME is caused only by enteroviruses.

 

Not necessarily. My understanding is that we no longer have the virus, so the cause is no longer what is keeping us ill. Our physiopathology might share similar pathways to PEM.

 

I can’t believe he is getting air time as he has lost his license to practice medicine.
https://doctors.cpso.on.ca/DoctorDetails/Byron-Marshall-Hyde/0016579-21364

 

Yeah i was surprised when he said that up until 1905 doctors didn't believe in infectious disease (4:23). That can't be true right?

 

Dr. Hyde from the interview:

He says that, as opposed to polio, which injures the nerve endings of the anterior part of the spinal cord, the injury is to the small blood vessels going to that area.

I found this interesting for a couple of reasons.

First, it sounds very much like Dr. Systrom's hypothesis for why blood returning to the hearts of ME patients has too much oxygen. Something is restricting oxygenated blood from reaching the smallest of blood vessels and the capillary bed - so, some of the oxygen is never delivered and it returns to the heart.

Second, this was also Dr. Ryll's explanation for a viral outbreak of "infectious venulitis" (which he believed was an ME variant) in a Sacramento, CA hospital and environs in 1975. In some of these cases, frank bruising was visible on the surface of the skin - a feature which distinguished it from typical ME.

The idea that constriction of the microcirculation is a factor in ME has been around for a while. I know there have been studies on it in the last decade or so - most concerned with nitric oxide and its relation to endothelial dysfunction. A writeup by Cort at PR regarding a 2020 study can be found here.

I'm not sure if it could be called "inflammation," since the actual effect seems to be to reduce the blood supply at the smallest scales. Something would be causing the constriction of tinniest blood vessels, but it couldn't be so complete and pervasive as to actually kill cells wholesale. It would just impair their function.

I have no idea if this is, in fact, a part of the ME puzzle, but it does keep showing up from different directions.


ETA: Link the to 2020 study: Peripheral Endothelial Dysfunction in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome

 

The research into polio was held up for decades because the leading researcher in the US did not believe in infectious organisms.

I think Dr Hyde gave up his license to practice rather than fight allegations and an awful lot of ME doctors have had allegations made against them.

He is very old now, most doctors who had knowledge of enteroviruses are gone and his insight is still useful as there is very little modern research. It is like the problems with the upsurge of TB. The bacteria could only be detected by an antiquated test that took 6 weeks before it gave a result. Enteroviruses have much the same problem.

 

The problem is that it shows up in different directions. Which is no use as science, which relies on things being consistent.

Dr Hyde is making things up as he goes along. There is no scientific evidence here of any value. The more patients quote Hyde the less they will be taken seriously.

 

I read the chapters that are available and it's unprofessionally written. There's also no data or references for many of the claims he makes.

 

Post copied from IIMEC 2023: Maureen Hanson

Dr.Byron Hyde

Non-Infectious M.E. Type Disease: I have not discussed noninfectious M.E.-type disease. Similar M.E phenomena can occur due to CNS injuries from toxic chemical injury. I have seen this in police officers who have fallen into toxic chemical ponds in pursuit of those suspected of criminal activity. I have seen it in farmers repeatedly exposed to pesticides and herbicides, in hospital and industrial workers and in military personnel in contact with toxic chemicals, specifically toxic gases. I will discuss these at a later date as Secondary M.E. They do have one thing in common, and that is they also have a diffuse CNS injury as noted on brain SPECT scans. The diagnosis is made by history, as the actual cases are very difficult to diagnose due to the inability to assess brain levels of toxins in a live patient. Often these Secondary M.E. diseases are more severe than the infectious M.E. cases.

 

Moved post

Has there anyone somewhat qualified ever explained why the SPECT scan results by Hyde are "no evidence"?

 

Merged thread

Is ME Non-paralytic Polio?

According to Dr Byron Hyde, ME is nonparalytic polio. I have read his book Understanding ME.
It does explain the epidemic form of ME I suppose. Whether I believe him though or not idk.

 

99% of polio was non-paralytic and bore no resemblance to ME.
Very few people take Dr Hyde seriously on this. He has never produced any evidence as far as I know.