I'm sure there was some internet commenter who used to talk a lot about 'the NO/ONOO(−) cycle' being important in ME/CFS, but it was never clear if they really had any evidence to support this, and it's not a claim I normally see in papers. Pretty sure I've been free of benzodiazepines anyway!
My doctor recommended that I get off of benzodiazepines some time ago. I'll write more about it 'someday'.
Well this certainly makes me feel a bit worried. Been taking them for 18 months now, they are the only thing helping me since my illness got severe. Guess it can always get more severe. FML
I wouldn't worry about it just on the basis of this paper (although all drugs can have side-effects it's worth being aware of).
I was just about to start taking clonazapem again because it is the only drug I have found helpful throughout my time with illness. In searching for a possible reason I discovered that GABA downregulates T cells which I thought was very interesting given the Mark Davis research into clonal T cell expansion.