Long COVID Treatment Guide (Patient-Led Research Collaborative & RTHM)

[Dolphin]

Long COVID Treatment Guide

An evidence-supported guide covering treatments addressing multiple Long COVID symptoms & mechanisms — focused on prescription medication, with a limited set of supplements, OTC medications, procedures, and lifestyle modifications included for breadth.

www.rthm.com

 

[forestglip]

A long list of treatments presented as if they may be helpful. Treatments were selected for inclusion based on if they were highly rated in the TREATME study, with some other supporting evidence added.

This Long COVID treatment guide is meant to spark meaningful conversations with patients and their clinicians about potential treatment options that could become part of a personalized care plan.

We chose the treatments in this guide using a combination of clinical evidence (reviewed up until Nov 2025), observed real-world effectiveness, and experience treating people with Long COVID. We focused on treatment options from the Harvard/Stanford TREATME Study (PMID: 40627388) that at least 20% of participants with Long COVID reported moderate to substantial benefit.

Additionally, we included treatments that show meaningful promise in clinical practice, or that have shown benefit in other infection-associated chronic conditions.

Probably helpful for RTHM's business:

Edit: Added quotes and made wording more accurate.

 

[Trish]

This is getting ridiculous. Since when is a social media survey the basis for 'evidence based' treatment? The world has gone mad.

 

[forestglip]

The paragraph describing RTHM at the bottom:

RTHM is a pioneering telehealth clinic and HIPAA-compliant intelligence platform dedicated to complex chronic illnesses like Long COVID, ME/CFS, POTS, and MCAS, offering personalized treatment suggestions, diagnostic paths, symptom tracking, and care team collaboration powered by the latest research. Cofounders Dr. Ryan Kellogg and Dr. Jennifer Curtin drew from their personal journeys through dismissed symptoms and scarce answers in a broken system. By blending their lived experiences and clinical expertise, they transformed a vision for accessible, science-driven care into a growing community and medical home for complex illnesses.

They don't seem to mention that they prescribe medications in the list of services they offer.

 

[Hutan]

Oh, good grief. This guide, prepared in collaboration with the Patient-Led Research Collaborative, is giving 'patient-led research' a bad name. Please do better, you are causing harm.