Suggested Pathology of Systemic Exertion Intolerance Disease [...] (2019) Bohne

It could, but I am not aware that we have evidence for any consistent shift in lactate in ME. I don't understand the concept of 'instantaneous changes' raised in the document.

 

Spotted this wiki-article about the journal in another debate about this paper.

Medical Hypotheses is a non-peer reviewed medical journal published by Elsevier. It was originally intended as a forum for unconventional ideas without the traditional filter of scientific peer review, "as long as (the ideas) are coherent and clearly expressed" in order to "foster the diversity and debate upon which the scientific processthrives."[2] Medical Hypotheses was the only Elsevier journal that did not send submitted papers to other scientists for review.[3] Articles were chosen instead by the journal's editor-in-chief based on whether he considered the submitted work interesting and important. The journal's policy placed full responsibility for the integrity, precision and accuracy of publications on the authors, rather than peer reviewers or the editor.[4]

https://en.wikipedia.org/wiki/Medic...EW6SGWzoUWCopPZ7KHs80FGOLr4Tnk921JMxYHg7LzBbg

 

Moved from deleted duplicate thread

Since we're all thinking it: What would I theoretically have to supplement to speed up DHLA regeneration? Would ALA or R-ALA supplementation increase pools at first and then be potentially damaging due to increased DHLA accumulation?

Yes I know it is too early to speculate no one knows and so on. But I can't be the only one thinking about that right now

 

I think this 2016 articles gives some background about the authors: https://www.av-avis.no/magasin/i/lR...Na-kan-ekteparet-pa-Askoy-ha-funnet-redningen

 

This is kind of interesting, so i wrote a Canadian professor in biochemistry if he could look at the Bohne paper. He said that the hypothesis in the paper is very vague;
that the entire paper lacks scientific rigour. And he doesn’t see any compelling reason to pinpoint the
particular catalytic step that Bohne focus on as the one primarily responsible.

 

Do we have any news with respect to oxalates? Has anyone tried supplementing it?