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Me too. Try it again @ProudActivist, as Sci hub seemed a bit flaky for me recently.

There are facts, and there are what can seem like terribly obvious extrapolations from those facts, so much so it can sometimes be very hard to realise they are not themselves facts. Science is about getting to the truth, completely independent of what might seem obvious or otherwise. PACE is a...

If it's not medical then I could maybe assist.

Interesting. But presumably only wise to do under medical advice / supervision.

Almost seems like a milestone (one of many) that advocacy efforts should set. Tightly focus on getting headline writers getting to consistently get this right. If we could get them to understand why it is important, then that would have significant pull-through effects I would think. In fact...

As this thread progresses, but by no means this thread in isolation, it really makes me believe that researching into ME should, to serious scientists, be a truly exciting and highly worthwhile challenge. The BPS'ites have made their crass attempts to suggest scientists are being scared off of...

The emphasis being on the 'all' I imagine. I could imagine the slightly crazy, but not that crazy, possibility, that "the something" could be something not even formally specified to be part of the process, but that might nonetheless typically be done during most such procedures. Being...

I guess it is a problem for witch doctors, when their patients refuse to believe what they are told to believe.

This I find fascinating, fully acknowledging all the caveats and concerns of course. If neck fixation actually did induce ME remission for some people, then of course the $64k question would be by what mechanism? Would it necessarily be due to the neck actually becoming fixed? Or alternatively...

These sound familiar ... What's less familiar is that the study has been retracted, and very clearly so.

Although it doesn't state evidence of validity for what, I assumed they are saying it's valid for assessing depression etc, and coyly avoiding saying it is not valid for CFS.

Very odd! It's actually well worth reading. Can you get to https://stats.idre.ucla.edu/ and then browse through ... Resources -> Frequently Asked Questions -> General FAQs -> Other statistical questions -> What are the differences between one-tailed and two-tailed tests?

My wife's fine motor control is good, she can do fine needlework etc. But her legs have been an issue since she got ME. Told me it was like having to learn to walk all over again, having to consciously think through putting one leg in front of another; she also uses a stick. And whereas once she...

He'll probably end up with a knighthood :sick:.

In my efforts to better understand, also found this: https://stats.idre.ucla.edu/other/mult-pkg/faq/general/faq-what-are-the-differences-between-one-tailed-and-two-tailed-tests/ Still trying to get an intuitive grasp of why, for a one-tailed test, it is OK to 'steal' the other tail's 2.5% to...

Yes, the thought also crossed my mind that it just could be the processes that have been undergone having some unknown beneficial effects, rather than the surgery per se. Would not be the first time improvements / cures have been stumbled upon without knowing why at the time.

Pretty sure have cropped up in S4ME before.

A nice quote, amongst a good many: "Then, he'll fix it. You can expect 70% improvement after the first day and by the end of the third day 85% are fixed.*(Unfortunately, Phil seems to have pulled these numbers out of his arse.)"

Ultimately ME is diagnosed by whether you meet a set of diagnostic criteria, and if you do then you have been 'correctly' diagnosed. Until we know any better diagnostic method, then that's the best can be done. There may well be all sorts of things meet the criteria - definitely confusing.

I think here she might be saying: a) British medicine in a phase where it arrogantly presumes inaccuracies don't matter, when of course they do. b) The 4-week protocol is maybe symptomatic of that arrogance, and that is currently how it works, even though it is cr*p. c) Given 'a' and 'b', they...