coagulation

Platelet defects in patients and mice with Ehlers-Danlos syndrome Ehlers-Danlos syndrome (EDS) is a group of connective tissue disorders characterized by joint hypermobility, skin hyperelasticity, perivascular tissue fragility, easy bruising, and increased bleeding risk. Abnormal bleeding in...

Background and Objectives: Post-COVID-19 syndrome (PCS), characterized by persistent fatigue, can develop after a SARS-CoV-2 infection. Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a chronic, post-infectious condition marked by severe fatigue and post-exertional malaise. This...

CD169+ and HLA-DR+ extracellular vesicles are highly represented in human plasma and dynamically expressed in SARS-CoV-2 infection and long COVID-associated sequelae INTRODUCTION Elevated inflammation and immune dysregulation are the main consequences of severe acute respiratory syndrome...

Widespread ncaas Imprints in the Serum Proteome of COVID-19 Convalescents Uncovering Immune System Sequelae Post-COVID-19 sequelae has become an emerging global health issue, but the mechanisms for the sustained susceptibility of convalescents to the sequelae remain poorly understood. Here we...

Activation of the Lectin Pathway Drives Persistent Complement Dysregulation in Long COVID Long COVID affects a substantial proportion of survivors of acute infection with severe acute respiratory syndrome-associated coronavirus-2 (SARS-CoV-2), who suffer a variety of symptoms that limit their...

Salivary cortisol in long COVID: a marker of broader stress system and circadian rhythm dysregulation INTRODUCTION Long COVID (LC) has been associated with hypothalamic–pituitary–adrenal (HPA) axis dysfunction, although findings from blood cortisol measurements remain inconsistent. We...

A chronobiology-based protocol for multi-omic mapping of menstrual cycle and diurnal rhythms in ME/CFS and long COVID Abstract Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and long COVID are debilitating multisystem illnesses with overlapping symptoms and poorly understood...

Long COVID and Reduced Thrombosis in Antihistamine Treated Patients: An Observational Study in the Metropolitan Area of Barcelona BACKGROUND Early evidence from a nursing home in Yepes (Toledo, Spain) indicated that antihistamines combined with azithromycin prevented deaths and...

Blood pro-thrombotic analytes and platelet activation are associated with post-acute sequelae of COVID-19 Post-Acute Sequelae of COVID-19 (PASC), or “long COVID,” describes persistent symptoms following recovery from SARS-CoV-2 infection. Early identification of circulating biomarkers...

Omics-based computational approaches for biomarker identification, prediction, and treatment of Long COVID Long COVID, or post-acute sequelae of COVID-19 (PASC), is a major global health problem, with cumulative estimates suggesting that around 400 million people worldwide have been affected...

A Comparative Study of the Coagulation Systems and Inflammatory Profiles of Patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and Patients with Long COVID Hayley Emma Arron Supervisor: Prof. Etheresia Pretorius Stellenbosch University [Line breaks added] Abstract Myalgic...

Exploring predictors of post-COVID-19 condition among 810 851 individuals in Sweden BACKGROUND Long-term effects of COVID-19 can place burden on individuals, healthcare, and society. We aimed to evaluate the importance of a wide range of potential risk factors for being diagnosed with...

https://journals.lww.com/plasreconsurg/fulltext/2025/11000/incidence_of_postoperative_venous_thromboembolism.21.aspx Reconstructive: Trunk: Original Article Incidence of Postoperative Venous Thromboembolism following Panniculectomy in Patients with History of COVID-19 Newland, Mary BS1; Lee...

Discovery of molecular signature of long-term psychiatric sequelae in COVID-19 through proteome profiling of dried blood spots Neuropsychiatric sequelae represent a significant aspect of post-acute sequelae of SARS-CoV-2 (PASC, or long COVID), posing considerable public health challenges. This...

https://academic.oup.com/immunohorizons/article/9/10/vlaf044/8256436?login=false Abstract Hypermobile Ehlers–Danlos Syndrome (hEDS) is a poorly understood connective tissue disorder that lacks molecular diagnostic markers. This study aimed to identify proteomic signatures associated with...

Abstract Coagulation, although primarily regulated by platelets, endothelial cells, and clotting factors, can also be influenced by molecules that are not traditionally seen as related to coagulation, including cytokines, hormones, metabolites, reactive oxygen species, acute phase reactants, and...

Regulation of m7G methylation in long COVID: Expression profiles and early predictive value of key genes Bai, Wenmei; Li, Fengsen Long COVID (LC) poses ongoing public health challenges due to its persistent symptoms following severe acute respiratory syndrome coronavirus 2 infection. Early...

Molecular Insights into Long COVID: Plasma Proteomics Reveals Oxidative Stress, Coagulation Cascade Activation, and Glycolytic Imbalance Sheela Ramanathan; Mohammad Mobarak Hussain Chowdhury; Akouavi Julite Irmin Quenum; Christine Rioux-Perreault; Jean-Francois Lucier; Subburaj Ilangumaran...

Integrative Bioinformatics Analysis Identifies Peripheral Blood Hub Genes and Establishes a Five-Gene Diagnostic Model for Long COVID Yang Liu, Yuwei Shen, Peilian Cao, Yuqiang Qian, Yutong Chen, Daxing Jiang, Jianan Li [Line breaks added] Background Long COVID (LC) is a multisystem condition...

Is COVID-19 Coagulopathy a Thrombotic Microangiopathy? A Prospective, Observational Study Silingardi, Mauro; Zappulo, Fulvia; Dormi, Ada; Pizzini, Attilia Maria; Donadei, Chiara; Cappuccilli, Maria; Fantoni, Chiara; Zaccaroni, Stefania; Pizzuti, Valeria; Cilloni, Nicola; Tantillo, Simona; Guidi...