covid

Metformin reduces SARS-CoV-2 in a Phase 3 Randomized Placebo Controlled Clinical Trial Carolyn T Bramante; Kenneth B Beckman; Tanvi Mehta; Amy B Krager; David J Odde; Christopher J Tignanelli; John B Buse; Darnell M Johnson; Ray H B Watson; Jerry J Daniel; David M Liebovitz; Jacinda M Nicklas...

Discontinuation of Universal Admission Testing for SARS-CoV-2 and Hospital-Onset COVID-19 Infections in England and Scotland Theodore R. Pak; Chanu Rhee; Rui Wang; Michael Klompas Link | PDF (JAMA Internal Medicine)

Access to individual patient-level data (IPD) of randomized clinical trials (RCTs) increases the reproducibility of research, facilitates exploration of effect modifiers, and leverages research investments beyond the original research question. This study aimed to describe access to IPD of RCTs...

Perceived Cognitive Deficits in Patients With Symptomatic SARS-CoV-2 and Their Association With Post–COVID-19 Condition Teresa C. Liu, Sun M. Yoo, Myung. S. Sim, Yash Motwani, Nisha Viswanathan, Neil S. Wenger Abstract Importance Neuropsychiatric symptoms are common in acute SARS-CoV-2...

(Oh the irony) More than 30 people who attended a conference organized by the CDC's "disease detectives" likely were infected with COVID-19 at the event last week, the agency said. The CDC hosted the 4-day conference that started April 24 at a Crowne Plaza hotel just outside Atlanta, which is...

Cardiopulmonary, Functional, Cognitive and Mental Health Outcomes Post-COVID-19, Across the Range of Severity of Acute Illness, in a Physically Active, Working-Age Population Oliver O’Sullivan, David A. Holdsworth, Peter Ladlow, Robert M. Barker-Davies, Rebecca Chamley, Andrew Houston, Samantha...

Preprint Incident autoimmune diseases in association with a SARS-CoV-2 infection: A matched cohort study Falko Tesch, Franz Ehm, Annika Vivirito, Danny Wende, Manuel Batram, Friedrich Loser, Simone Menzer, Josephine Jacob, Martin Roessler, Martin Seifert, Barbara Kind, Christina König, Claudia...

Link and abstract of the study is posted later in the thread, here. BBC: Covid: No evidence shielding helped - Swansea uni study quote: Swansea University compared 117,000 people shielding in Wales with the rest of the population of three million. The study found deaths and healthcare usage...

Journal of Biomedical Informatics PASCLex: A comprehensive post-acute sequelae of COVID-19 (PASC) symptom lexicon derived from electronic health record clinical notes Liqin Wang, Dinah Foer, Erin MacPhaul, Ying-Chih Lo, David W. Bates, Li Zhou Abstract Objective To develop a comprehensive...

[Moderators - This article is about COVID-19 reinfection. I posted in the Long Covid forum because of the final section that talks about Long Covid. But please move it if it belongs elsewhere.] What doctors wish patients knew about COVID-19 reinfection...

People who haven't had COVID will likely catch XBB.1.5 – and many will get reinfected, experts say Variant XBB.1.5 is very contagious, meaning everyone is at risk even if you've already been infected. As the U.S. enters year 3 of the pandemic, here's an update on the state of COVID. KAREN...

CDC Maps: From Red to Green Comparison of two of the CDC maps (community transmission vs community levels) that are available on the CDC website and displayed on their social media. FYI, this video is new, and the discussion is timely, even though the CDC made these map changes to show new...

Some threads have been merged to create this news thread The future of the NHS: no longer the envy of the world? Picked up from social media. Article in the Lancet London School of Economics have this project with an independent commission looking to identify big challenges faced by the NHS...

Not sure exactly where to post this article since it covers a lot of things! This forum seemed best because of the title (pandemic), but please move if there's a better place. Perhaps the forum for Long Covid news? This article is a response to Biden's statement on 60 Minutes that the pandemic...

Full title: The chronification of post-COVID condition associated with neurocognitive symptoms, functional impairment and increased healthcare utilization Abstract Post-COVID condition is prevalent in 10–35% of cases in outpatient settings, however a stratification of the duration and...

New op-ed in The Philadelphia Inquirer by Jennie Spotila: Let’s approach COVID like the weather. Depending on conditions, we grab an umbrella (or mask) Tweet from the author:

Abstract The pathophysiology of COVID-19-associated coagulopathy is complex and not fully understood. SARS-CoV-2 spike protein (SP) may activate platelets and interact with fibrin(ogen). We aimed to investigate whether isolated SP can be present in clots retrieved in COVID-19 patients with...

The Pfizer press release reports that protection is achieved 28 days after initiation of the first dose of vaccine. Whereas you can develop covid within a few days of exposure, so the virus wins that race...

https://www.nature.com/articles/s41586-022-05128-8

Full title: Long COVID and the cardiovascular system – elucidating causes and cellular mechanisms in order to develop targeted diagnostic and therapeutic strategies: A joint Scientific Statement of the ESC Working Groups on Cellular Biology of the Heart and Myocardial & Pericardial Diseases...