ebv

Abstract Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a disease of unknown aetiology associated with chronic severe fatigue and neurological symptoms, including dizziness, sleep disturbances, cognitive impairment and pain. There are no reliable blood biomarkers available for...

Defective B cell tolerance in SLE lymph nodes underpins VH4-34 "clonal damnation" and PD-1+TOX+ autoreactive B cells expansion. Systemic Lupus Erythematosus (SLE) is a chronic autoimmune disease driven by uncensored B and T cell autoreactivity. Understanding this pathogenic process has been...

Transgenic mouse-derived human monoclonal antibodies targeting EBV gp350 and gp42 provide basis for therapeutic development Highlights • Transgenic mice were used to make genetically human EBV mAbs against gp350 and gp42 • mAbs potently neutralize EBV infection by blocking receptor-ligand...

Immune-metabolic trajectories delineate subgroups in paediatric long COVID Most children and adolescents recover rapidly from SARS-CoV-2 infection, yet a subset develops paediatric long COVID (LC). How immune ontogeny shapes LC biology and heterogeneity remains unclear. We deeply phenotype a...

Full title: The composition of MDSC-subpopulations PMN-like, M-like, and e-like MDSC is associated with the severity of infectious mononucleosis in pediatric patients Abstract Background: Primary infection with the Epstein-Barr virus (EBV) in early childhood is often asymptomatic, whereas...

Comparing ME/CFS following mononucleosis with Long COVID Jason, Leonard A; Furst, Jacob; Katz, Ben Z Objectives Long COVID following SARS-CoV-2 and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) following infectious mononucleosis (IM) are examples of post-infectious chronic...

Clinical relevance of circulating blood microaggregates and reactivation of Epstein Barr Virus in long-term Post-CoVID syndrome patients Abstract Chronic persistence of systemic symptoms after recovery from active CoVID-19 has become a significant disease burden, named post-CoVID syndrome...

https://www.tandfonline.com/doi/full/10.1080/10253890.2026.2638303 Research Article The association between hair cortisol levels, Epstein-Barr virus infections and chronic fatigue in adolescents Berit Elise Bergem Kongsnes , Tarjei Tørre Asprusten , Vegard Bruun Bratholm Wyller & Maria...

Background and Objectives: Post-COVID-19 syndrome (PCS), characterized by persistent fatigue, can develop after a SARS-CoV-2 infection. Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a chronic, post-infectious condition marked by severe fatigue and post-exertional malaise. This...

Diminished EBV-Specific Humoral Immunity is Associated with Neuropsychiatric Long COVID Development up to 12 Months Post-COVID-19 Symptom Onset [Line breaks added] Abstract Infection with SARS-CoV-2 can lead to long COVID, a chronic multisystemic condition estimated to affect approximately...

Epstein Barr virus, infectious mononucleosis and associated diseases as contributors to the costs of intimate kissing Ewald, Paul W. [Line breaks added] Abstract When evaluating whether kissing is an evolutionary adaptation, fitness costs and benefits need to be considered. Any disease...

Abstract Multiple sclerosis (MS) occurs when the central nervous system (CNS) is damaged by misguided adaptive immune responses, likely caused by a combination of environmental factors in genetically susceptible individuals. A known prerequisite for disease is Epstein-Barr virus (EBV)...

Myelin antigen capture in the CNS by B cells expressing EBV latent membrane protein 1 leads to demyelinating lesion formation The efficacy of B cell depletion therapies, and their association with Epstein-Barr virus (EBV), implicate B cells in the pathogenesis of multiple sclerosis (MS). In...

Epstein Barr viral shedding dynamics in saliva during acute SARS-CoV-2 infection BACKGROUND Epstein−Barr virus (EBV) establishes latency in most adults and can be reactivated under conditions of co-infection and immune dysregulation. COVID−19 has been associated with EBV reactivation...

SARS-CoV-2 Infection Is Associated With an Increased Risk of Hospital-Treated Infectious Mononucleosis due to EBV: National Register-Based Cohort Study There is evidence that persistent dysregulation of the immune system caused by SARS-CoV-2 infection may increase susceptibility to other...

Abstract Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating multisystem illness with unknown etiology. An estimated 17–24 million people representing approximately 1% of the population are afflicted worldwide. In over half of cases, ME/CFS onset is associated with...

Abstract: Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a chronic and debilitating disease with unknown cause. Involvement of infection and immune dysregulation has been suggested, including changes in immune cell subsets and abnormal functions of natural killer (NK) cells. The...

Abstract Epstein–Barr virus (EBV) may cause harm in immunocompromised conditions or on stress stimuli. Various chemical agents have been utilized to induce the lytic cycle in EBV-infected cells. However, apart from chemical agents and external stress stimuli, certain infectious agents may...

Seems like the literature is confusing here. Consensus seems to be that no antivirals (AV) are effective against EBV. https://pmc.ncbi.nlm.nih.gov/articles/PMC6429425/ But then there are case studies showing certain AVs are effective. https://academic.oup.com/jid/article/216/2/198/3858428...

T and B cell responses against Epstein–Barr virus in primary sclerosing cholangitis [Line breaks added] Abstract Primary sclerosing cholangitis (PSC) is an idiopathic, progressive and incurable liver disease. Here, we aimed for systematic analyses of adaptive immune responses in PSC. By...