I hope the Mods won't mind me creating a thread for this blog, which looks at why genetic studies are so important. Posted for British Science...
not listened to it so no idea of content. In this episode I welcome on Dr. Richard Boles. Dr. Richard G. Boles is a medical geneticist and a...
Abstract Irritable bowel syndrome (IBS) results from disordered brain–gut interactions. Identifying susceptibility genes could highlight the...
Quote: An innovative type of medicine - called gene silencing - is set to be used on the NHS for people who live in crippling pain. The drug...
As people may have heard in the news, a new study launched yesterday called Spectrum10k. I thought I'd post it here in case any of our autistic...
Full title: Fine mapping of the major histocompatibility complex (MHC) in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) suggests...
Paroxysmal exercise-induced neurological symptoms (PENS) encompass a wide spectrum of clinical phenomena commonly presenting during childhood and...
Identification of differential genetic profiles in severe forms of fibromyalgia and chronic fatigue syndrome/myalgic encephalomyelitis: A...
Abstract Background and Objectives Chronic widespread musculoskeletal pain (CWP) is a symptom of fibromyalgia and a complex trait with poorly...
Highlights • ME/CFS is characterized by skewed B cell receptor gene usage. • Upregulation of specific IGHV genes correlated to infection-related...
" Abstract Importance Psychotic experiences, such as hallucinations and delusions, are reported by approximately 5%-10% of the general population,...
Abstract Cerebrovascular pathologies occur in up to 80% of cases of Alzheimer's disease; however, the underlying mechanisms that lead to...
Abstract It is tempting to mine the abundance of DNA data that is now available from direct-to-consumer genetic tests, but this approach has its...
Abstract Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a complex multisystem illness that lacks effective therapy and a...
I'm looking for evidence for a genetic component in ME/CFS and a discussion of the quality of evidence for each the studies. Here are some I...
Background: Small fiber polyneuropathy (SFN) involves ectopic firing and degeneration of small-diameter, somatic/autonomic peripheral axons....
Alterations in cellular energy metabolism have been implicated in chronic pain suggesting a role for mitochondrial DNA (mtDNA). Previous studies...
Moderator note: Please note: at this point only people from the UK will be eligible to participate in the study. However people from...
Provisionally accepted opinion article in frontiers in Pediatrics - Paediatric Neurology Review of the Quality Control Checks Performed by...
https://www.frontiersin.org/articles/10.3389/fimmu.2020.00578/full Excerpt: In conclusion, our study shows that the PTPN22 rs2476601 and CTLA4...
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