genetics

  1. Andy

    Mechanistic Insights into the Pathophysiology of CFS/ME: Examining Nrf2 Antioxidant Gene Expression & its Role in Combating Oxidative Stress, ongoing

    Struggling at the moment to find more details about this, if/when I do I'll edit them in here. From https://cureme.lshtm.ac.uk/researchers/our-collaborative-researchers/ ETA: Added detail from the CureME collaborators page.
    • Andy
    • Thread
    • 2019 cardiology faisel khan genetics me/cfs nrf2 oxidative stress
    • Replies: 4
    • Forum: ME/CFS research
  2. MeSci

    Treatment avenues in ME/CFS: A split-gender pharmacogenomic study of gene-expression modules, 2019, Jeffrey, Broderick. Klimas et al

    Source: Clinical Therapeutics Preprint Date: March 6, 2019 URL: https://www.sciencedirect.com/science/article/abs/pii/S0149291819300475 Treatment avenues in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A split-gender pharmacogenomic study of gene-expression modules...
    • MeSci
    • Thread
    • 2019 broderick gene expression genetics jeffrey klimas me/cfs paper treatment
    • Replies: 3
    • Forum: ME/CFS research
  3. Sly Saint

    Epstein-Barr virus induced gene-2 upregulation identifies a particular subtype of Chronic Fatigue Syndrome / Myalgic Encephalomyelitis (2019) Kerr

    Provisionally accepted https://www.frontiersin.org/articles/10.3389/fped.2019.00059/full full paper here: http://sci-hub.tw/https://www.frontiersin.org/articles/10.3389/fped.2019.00059/full I haven't read it all but not sure if I've posted it in the correct forum?: "EBV reactivation is a...
  4. Andy

    The Mirror: Veterans with debilitating Gulf War Syndrome may have passed it on to children

    https://www.mirror.co.uk/news/uk-news/veterans-debilitating-gulf-war-syndrome-13911872
  5. Chris Ponting

    Repurposing large health insurance claims data to estimate genetic and environmental contributions in 560 phenotypes (2019) Lakhani et al.

    I just wanted to highlight a paper that came out today in Nature Genetics: Lakhani et al. (“Repurposing large health insurance claims data to estimate genetic and environmental contributions in 560 phenotypes”). In this study, they used very large health insurance claims data to compare whether...
  6. Dolphin

    Lefever (2018) "Hypophosphatasia in adults: clinical spectrum and its association with genetics and metabolic substrates" (differential diagnosis)

    https://www.sciencedirect.com/science/article/pii/S1094695018302440
    • Dolphin
    • Thread
    • 2018 genetics hypophosphatasia lafever me/cfs metabolism paper
    • Replies: 0
    • Forum: ME/CFS research
  7. Andy

    Huge brain study uncovers ‘buried’ genetic networks linked to mental illness

    https://www.nature.com/articles/d41586-018-07750-x
  8. Andy

    A predictive algorithm to identify genes that discriminate individuals with fibromyalgia syndrome diagnosis from healthy controls, 2018, Saliqan et al

    Open access at https://www.dovepress.com/a-predictive-algorithm-to-identify-genes-that-discriminate-individuals-peer-reviewed-fulltext-article-JPR
  9. F

    Is there a link between allergies and ME/CFS?

    Having read this article on Allergies, The scourge of modern living I found it fitted in with my line of thinking about ME/CFS. I hope I don’t lose the excellent value of the article by summarising it as follows; Food allergies are on the increase in the modern world. Why might something as...
  10. Binkie4

    Genome-epigenome interactions associated with ME/CFS, 2018, McGowan et al.

    https://www.tandfonline.com/doi/full/10.1080/15592294.2018.1549769?scroll=top&needAccess=true Abstract published. Article behind a paywall. Research financed by Solve ME/cfs.
    • Binkie4
    • Thread
    • 2018 epidemiology genetics mcgowan me/cfs paper solve mecfs initiative
    • Replies: 10
    • Forum: ME/CFS research
  11. Andy

    Associations between clinical symptoms, plasma norepinephrine & deregulated immune gene networks in subgroups of adolescent w/CFS, 2018, Nguyen et al

    Paywalled at https://www.sciencedirect.com/science/article/pii/S0889159118307967?via%3Dihub
    • Andy
    • Thread
    • 2018 genetics immunology me/cfs nguyen norepinephrine paper t-cells young people
    • Replies: 3
    • Forum: ME/CFS research
  12. Sly Saint

    Genetic determinism rides again - a psychologist’s troubling claims about genes and behaviour

    Nathaniel Comfort questions a psychologist’s troubling claims about genes and behaviour. 25 September 2018 https://www.nature.com/articles/d41586-018-06784-5 (not exactly related to this piece but I am reminded of Crawley saying that CFS is 'more genetically heritable in children')
  13. M

    Lysinuric protein intolerance

    https://rarediseases.info.nih.gov/diseases/3335/lysinuric-protein-intolerance https://ghr.nlm.nih.gov/condition/lysinuric-protein-intolerance I just wanted to start a discussion on this inborn error of metabolism.
  14. Sly Saint

    ME/CFS Genes Study- Institute for Neuro Immune Medicine

    Mentioned on another thread. ME/CFS Genes Study " We are currently recruiting ME/CFS patients AND Healthy Controls for this completely web based study to create a one of a kind genetic database for individuals with ME/CFS. Participation for this study requires you to have a computer with...
  15. M

    Functional Interrogation of Primary Human T Cells via CRISPR Genetic Editing (2018)

    Functional Interrogation of Primary Human T Cells via CRISPR Genetic Editing Dr Unutmaz is one of the principal investigator of this paper. http://www.jimmunol.org/content/early/2018/07/18/jimmunol.1701616?papetoc Abstract: Abstract Developing precise and efficient gene editing approaches...
  16. Webdog

    Organic solvents and MS susceptibility: Interaction with MS risk HLA genes (2018) Hedström et al.

    Study: http://n.neurology.org/content/early/2018/07/03/WNL.0000000000005906 Summary: https://www.nationalmssociety.org/About-the-Society/News/Study-Finds-Exposure-to-Organic-Solvents-Smoking The genes that have been shown to affect MS susceptibility include HLA genes. Thought the HLA link...
  17. Webdog

    Article: How CRISPR Tools are Unlocking New Ways to Fight Disease

    https://www.ucsf.edu/news/2018/07/411031/crispr-toolkit-unlocks-new-ways-fight-disease
  18. Andy

    Nature: A series of five Reviews [..] discuss the genetic, environmental, microbial, and cellular factors underpinning autoimmune disease

    https://www.nature.com/collections/zbpsndwbnq/
  19. Simon M

    Ron Davis’s big immune study is looking at HLA genes (HLA, WTF?) Here’s the story. [Simon M blog]

    New blog at ME/CFS Research Review Dr Ron Davis has won a large NIH (US National Institutes of Health) grant for an immunology project with a strong focus on HLA genes. Which may have led some to wonder, ‘What are they?’ HLA (human leukocyte antigen) molecules play a critical role in the...
  20. J

    A naturally occurring antiviral ribonucleotide encoded by the human genome (2018) Anthony S. Gizzi et al

    May be of interest. https://www.nature.com/articles/s41586-018-0238-4 Abstract Viral infections continue to represent major challenges to public health, and an enhanced mechanistic understanding of the processes that contribute to viral life cycles is necessary for the development of new...
Back
Top Bottom