https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220254/ Very interesting paper which has identified MYSM1, a part of the ubiquitin system that acts...
An interesting correlation between use of these medications and reduced symptoms in a large scale study. One proposed mechanism is a reduction in...
Not sure if this is of any relevance. Impaired immune surveillance accelerates accumulation of senescent cells and aging Yossi Ovadya, Tomer...
Not sure whether this is really relevant, but the reference to kynurenine looked interesting. NB participants include some dodgy people, e.g....
Highlights •Erythrocyte omega-3 index (5.75%) and n-3 PUFA levels are low in individuals with CFS/ME. •The erythrocyte omega-3 index may be a...
This may be interesting for some given the changes in metabolism . Tagging @mariovitali re LXR role...
Abstract: Background: Increased intestinal permeability with heightened translocation of Gram-negative bacteria, also known as “leaky gut”, is...
Abstract The initiation of intestinal inflammation involves complex intercellular cross-talk of inflammatory cells, including the epithelial and...
Abstract Although serum from patients with Parkinson’s disease contains elevated levels of numerous pro-inflammatory cytokines including IL-6,...
Initially I looked at this for the amusement factor but improved gut health and lower inflammation might be of interest. Abstract Edible insects...
The innate immune response mounts a defence when immune cells recognize general hallmarks of infection, such as lipopolysaccharide (LPS)...
It seems widely accepted that “stress” leads to inflammation. “Stress” in this context is always used to denote emotional stress. How does...
Researchers from the University of Illinois at Chicago have identified a protein that is crucial for activating inflammation—both the good kind of...
I thought this was interesting, particularly given Younger's upcoming study on neuroinflammation in ME, and also for the possibility of a future...
Based on mice research but at least sounds interesting. Summary: An immunization for stress created from beneficial bacteria could be on the...
George Brooks has been trying to reshape thinking about lactate—in the lab, the clinic and on the training field—for more than 40 years, and...
Summary Sleep and circadian abnormalities are prevalent and burdensome manifestations of diverse neuro-immune diseases, and may aggravate the...
Some immunologists regard the central nervous system (CNS) as a no-man’s-land, avoided by immune cells and therefore uninteresting. But, in fact,...
Inflammation can be good. It's part of the body's innate immune system, our first line of defense against illness and injury. However, if the...
May be of general background interest for some, Inflammation is a cellular and molecular response to infection and/or tissues injury. While a...
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