inflammation

  1. Sly Saint

    Gulf War Illness-associated increases in blood levels of interleukin 6 and C-reactive protein: biomarker evidence of inflammation- Bach et al Dec 2019

    full article here https://bmcresnotes.biomedcentral.com/articles/10.1186/s13104-019-4855-2
  2. Sly Saint

    Fatigue and sleepiness responses to experimental inflammation and exploratory analysis of the effect of baseline inflammation in healthy humans

    Brain, Behavior, and Immunity Volume 83, January 2020, Pages 309-314 https://www.sciencedirect.com/science/article/pii/S0889159119304507?dgcid=author
  3. G

    Connection between lactate, hypoxia, and inflammation

    https://www.nature.com/articles/s41577-019-0259-8?utm_source=dlvr.it&utm_medium=twitter
  4. mango

    Open Sweden: The role of low-grade inflammation [...] in ME/CFS, Andreasson et al - recruiting

    The role of low-grade inflammation for the progress of disease in patients with myalgic encephalomyelitis/chronic fatigue syndrome ME/CFS Anna Andreasson, Martin Jonsjö, Linda Holmström. Original title in Swedish (as stated in the ethical approval application): Betydelsen av låggradig...
  5. Andy

    Drugs that quell brain inflammation reverse dementia

    https://neurosciencenews.com/inflammation-drugs-dementia-15285/
  6. rvallee

    Inflammation and kynurenine pathway dysregulation in post-partum women with severe and suicidal depression, 2019, Achtyes et al

    https://www.sciencedirect.com/science/article/pii/S0889159119310773 From a press release by the university: https://www.vai.org/pregnancy-related-depression-lena-brundin/ Hello tryptophan my old friend. I frankly find it doubtful that cognition, thoughts and beliefs, play more than a minor...
  7. rvallee

    Selective effects of acute low-grade inflammation on human visual attention (2019) Balter et al.

    If those numbers are reliable this is a borderline epidemic level crisis. Nearly 1/5 of the UK population reporting significant cognitive symptoms interfering with daily life but are typically brushed off by medicine. The worldwide numbers would place this at above 1B. That's staggering...
  8. rvallee

    First evidence of immune response targeting brain cells in autism

    Preliminary but interesting. Autism has been researched far more than ME and somehow this had been missed entirely. I would really like to see research done on post-mortem ME brains and spinal cords. This is the reason the researchers named this disease and there doesn't seem to have been any...
  9. Sly Saint

    Fatigue severity in anti-nuclear antibody-positive individuals does not correlate with pro-inflammatory cytokine levels..., 2019, Hafiz et al

    Fatigue severity in anti-nuclear antibody-positive individuals does not correlate with pro-inflammatory cytokine levels or predict imminent progression to symptomatic disease Waleed Hafiz, Rawad Nori, Ariana Bregasi, Babak Noamani, Dennisse Bonilla, Larissa Lisnevskaia, Earl Silverman, Arthur...
  10. S

    Brain inflammation

    I seem to have weeks going into months of brain inflammation which is horrendous. My brain feels inflamed which at night particularly seems to go throughout my body, some of the day as well. The feeling is deeply uncomfortable and quite excruciatingly painful with some throbbing, spreads across...
  11. Kalliope

    Acta Neurologica Scandinavia: Inflammation and fatigue in early, untreated Parkinson's Disease - by Herlofson et al - 2019

    Inflammation and fatigue in early, untreated Parkinson's Disease Abstract Objectives Parkinson's disease (PD)‐related fatigue is a significant clinical problem, and the pathological processes that cause fatigue remain unknown. The aim of the present study was to explore the possible association...
  12. MeSci

    Epigenetic upregulation of FKBP5 by aging and stress contributes to NF-κB–driven inflammation and cardiovascular risk, 2019, Zannas et al.

    Epigenetic upregulation of FKBP5 by aging and stress contributes to NF-κB–driven inflammation and cardiovascular risk Anthony S. Zannas,a,b,c,d,1 Meiwen Jia,a Kathrin Hafner,a Jens Baumert,e Tobias Wiechmann,a Julius C. Pape,a Janine Arloth,a,f Maik Ködel,a Silvia Martinelli,a Maria Roitman,a...
  13. Andy

    General theory of inflammation: patient self-administration of hydrocortisone safely achieves superior control..., 2019, Irwin et al

    Full title: General theory of inflammation: patient self-administration of hydrocortisone safely achieves superior control of hydrocortisone-responding disorders by matching dosage with symptom intensity Open access at...
    • Andy
    • Thread
    • 2019 hydrocortisone inflammation irwin me/cfs paper steroids
    • Replies: 0
    • Forum: ME/CFS research
  14. E

    Autonomic and inflammatory changes in FM & ME/CFS and the contribution to signs & symptoms (BMJ, 2019) Themelis et al

    BMJ Journals: Annals of the Rheumatic Diseases: Autonomic and inflammatory changes in FM and ME/CFS and the contribution to signs and symptoms https://ard.bmj.com/content/78/Suppl_2/1920.1 Abstract Background Dysautonomia describes a group of conditions associated with a malfunction of the...
    • Eagles
    • Thread
    • 2019 dysautonomia fibromyalgia inflammation me/cfs paper themelis
    • Replies: 3
    • Forum: ME/CFS research
  15. Sly Saint

    Systemic low-grade inflammation and subsequent depressive symptoms: Is there a mediating role of physical activity? 2019 Frank Kaushal Chalder et al

    Systemic low-grade inflammation and subsequent depressive symptoms: Is there a mediating role of physical activity? https://www.researchgate.net/publication/333056434_Systemic_low-grade_inflammation_and_subsequent_depressive_symptoms_Is_there_a_mediating_role_of_physical_activity
  16. W

    What is the normal value of the neutrophil-to-lymphocyte ratio? (2017) Forget, De Kock, et al.

    Background Neutrophil-to-lymphocyte ratio (NLR) has proven its prognostic value in cardiovascular diseases, infections, inflammatory diseases and in several types of cancers. However, no cut-off has been proposed on the basis of reference values coming from healthy population. Methods Routine...
  17. Andy

    Review: Mitochondria: the indispensable players in innate immunity and guardians of the inflammatory response, 2019, Mohanty et al

    Paywalled at https://link.springer.com/article/10.1007%2Fs12079-019-00507-9 Sci Hub link, https://sci-hub.tw/https://link.springer.com/article/10.1007%2Fs12079-019-00507-9
  18. R

    Changes in the transcriptome of circulating immune cells of a NZ cohort with ME/CFS (2019) Sweetman et al

    I saw this posted on the "ME/CFS-Evolving Science" facebook page... Changes in the transcriptome of circulating immune cells of a New Zealand cohort with myalgic encephalomyelitis/chronic fatigue syndrome Eiren Sweetman, Margaret Ryan, Christina Edgar, Angus MacKay, Rosamund Vallings, Warren...
    • RoseE
    • Thread
    • 2019 circadian inflammation me/cfs metabolic dysregulation mitochondria mitochondrial dysfunction new zealand oxidative stress paper sweetman transcriptome
    • Replies: 21
    • Forum: ME/CFS research
  19. leokitten

    The deubiquitinase MYSM1 dampens NOD2-mediated inflammation and tissue damage by inactivating the RIP2 complex

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220254/ Very interesting paper which has identified MYSM1, a part of the ubiquitin system that acts as a molecular switch to deactivate the innate immune system and has the ability to prevent certain diseases caused by an excessive activation of the...
  20. Marco

    Statins, Metformin and Calcium Blockers may help Schizophrenia

    An interesting correlation between use of these medications and reduced symptoms in a large scale study. One proposed mechanism is a reduction in inflammation. Neuroscience News : https://neurosciencenews.com/statins-mental-health-10473/ SMC reaction ...
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