Summary: A synthesized small-molecule drug blocks the TGF-beta receptor in astrocytes and traverses the blood-brain barrier in mice. When...
https://www.sciencedirect.com/science/article/pii/S0889159119310773 Highlights • Severe peripartum depression (PPD) with suicidality is an...
Link between inflammation and mental sluggishness shown in new study An estimated 12M UK citizens have a chronic medical condition, and many of...
In a paper published in Annals of Neurology, Matthew Anderson, HMS associate professor of pathology at Beth Israel Deaconess Medical Center, and...
Fatigue severity in anti-nuclear antibody-positive individuals does not correlate with pro-inflammatory cytokine levels or predict imminent...
I seem to have weeks going into months of brain inflammation which is horrendous. My brain feels inflamed which at night particularly seems to go...
Inflammation and fatigue in early, untreated Parkinson's Disease Abstract Objectives Parkinson's disease (PD)‐related fatigue is a significant...
Epigenetic upregulation of FKBP5 by aging and stress contributes to NF-κB–driven inflammation and cardiovascular risk Anthony S. Zannas,a,b,c,d,1...
Full title: General theory of inflammation: patient self-administration of hydrocortisone safely achieves superior control of...
BMJ Journals: Annals of the Rheumatic Diseases: Autonomic and inflammatory changes in FM and ME/CFS and the contribution to signs and symptoms...
Systemic low-grade inflammation and subsequent depressive symptoms: Is there a mediating role of physical activity? Abstract Objective: Systemic...
Background Neutrophil-to-lymphocyte ratio (NLR) has proven its prognostic value in cardiovascular diseases, infections, inflammatory diseases and...
Abstract Mitochondria, the dynamic organelles and power house of eukaryotic cells function as metabolic hubs of cells undergoing continuous...
I saw this posted on the "ME/CFS-Evolving Science" facebook page... Changes in the transcriptome of circulating immune cells of a New Zealand...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220254/ Very interesting paper which has identified MYSM1, a part of the ubiquitin system that acts...
An interesting correlation between use of these medications and reduced symptoms in a large scale study. One proposed mechanism is a reduction in...
Not sure if this is of any relevance. Impaired immune surveillance accelerates accumulation of senescent cells and aging Yossi Ovadya, Tomer...
Not sure whether this is really relevant, but the reference to kynurenine looked interesting. NB participants include some dodgy people, e.g....
Highlights •Erythrocyte omega-3 index (5.75%) and n-3 PUFA levels are low in individuals with CFS/ME. •The erythrocyte omega-3 index may be a...
This may be interesting for some given the changes in metabolism . Tagging @mariovitali re LXR role...
Separate names with a comma.