inflammation

Full title: Sodium butyrate inhibits the NF-kappa B signaling pathway and histone deacetylation, and attenuates experimental colitis in an IL-10 independent manner In mice. Highlights • Butyrate inhibits the production of TNF-α, IL-6 and IL-12 in macrophages. • Butyrate inhibits NF-κB...

https://www.cell.com/cell/pdf/S0092-8674(21)01223-X.pdf Research done in mice. Highlights Neuronal ensembles in the InsCtx are activated during peripheral inflammation Reactivation of these neurons is sufficient to retrieve peripheral inflammation These InsCtx neurons project to autonomic...

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused the pandemic Coronavirus Disease 2019 (COVID-19) and now many face the burden of prolonged symptoms—long-lasting COVID-19 symptoms or “long-COVID”. Long-COVID is thought to be linked to immune dysregulation due to harmful...

Abstract Although most patients recover from acute COVID-19, some experience postacute sequelae of severe acute respiratory syndrome coronavirus 2 infection (PASC). One subgroup of PASC is a syndrome called “long COVID-19,” reminiscent of myalgic encephalomyelitis/chronic fatigue syndrome...

Activation of endogenous retroviruses during brain development causes an inflammatory response Marie E Jönsson, Raquel Garza, Yogita Sharma, Rebecca Petri, Erik Södersten, Jenny G Johansson, Pia A Johansson, Diahann AM Atacho, Karolina Pircs, Sofia Madsen, David Yudovich, Ramprasad...

Full title: The Reification of the Clinical Diagnosis of Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME/CFS) as an Immune and Oxidative Stress Disorder: Construction of a Data-Driven Nomothethic Network and Exposure of ME/CFS Subgroups https://www.preprints.org/manuscript/202101.0623/v1

https://www.huffingtonpost.co.uk/entry/covid-tongue-explained_uk_60016507c5b62c0057bc0be2?ncid=fcbklnkukhpmg00000001&fbclid=IwAR3KZkyFOqPM2vuwSrM_MVSvLoAM-U4nInQ5UtnlL3LzXEwPJYhWmlzOa4g&guccounter=1&guce_referrer=aHR0cHM6Ly9sLmZhY2Vib29rLmNvbS8&guce_referrer_sig=AQAAAGa517_TqWUBcV_ZrgqWanMDO6DeMe...

Lately I've been having attacks of red itchy inflammation. It doesn't look too bad on the pictures but it's sore and sometimes itches tremendously. I have very severe ME and although I've had very little light sensitivity, my sound sensitivity is worse and my touch sensitivity even worse. Having...

I'm asking this because this is what triggered a severe worsening of my symptoms at the time. It coincided with sporadic serum hyperpotassemia but no test or swap had been done on infections.

Interesting review of research on the impact of inflammation on the dopamine system as well as a theoretical model and computational method trying to connect it all. Could be a hypothesis as to why Abilify and dopaminergic agents have some partial efficacy in ME, even if it is temporary (so...

https://www.nature.com/articles/s41573-020-0082-8

https://link.springer.com/article/10.1007/s10753-020-01356-0 Original Article Published: 09 October 2020 Amitriptyline Downregulates Chronic Inflammatory Response to Biomaterial in Mice

Free full text: https://www.nature.com/articles/s41598-020-66532-6

Full title: Chronic fatigue and fibromyalgia symptoms are key components of deficit schizophrenia and are strongly associated with activated immune-inflammatory pathways I'd suggest that there is total conflation between chronic fatigue and 'chronic fatigue syndrome' here. Paywall...

Moderator note: Copied from this thread: "Cerebral blood flow is reduced in ME/CFS during head-up tilt testing even in the absence of hypotension or tachycardia... van Campen et al, 2020 _____________________________ There is this new article but sorry if it is old study news, I'm new to...

https://www.theguardian.com/commentisfree/2020/jan/19/inflammation-depression-mind-body

Paywall, https://www.sciencedirect.com/science/article/abs/pii/S1359610119301479 Sci hub, https://sci-hub.se/10.1016/j.cytogfr.2019.12.008

https://jnnp.bmj.com/content/91/1/21.abstract Efficacy and safety of anti-inflammatory agents for the treatment of major depressive disorder: a systematic review and meta-analysis of randomised controlled trials Hard to say whether this is GIGO without an in-depth look but this was to be...

https://www.sciencedirect.com/science/article/abs/pii/S0306453019313198

2011 paper Sustained 20 years, zero citations. Zero. “A unique case of coincidental splenectomy for trauma during chronic fatigue syndrome (CFS) is presented. The patient had a two-year history of CFS prior to her involvement in a road crash. Delayed rupture of the spleen ten days later...