long covid

Reduced athletic performance post-COVID-19 is associated with reduced anaerobic threshold Robert M Barker-Davies; Peter Ladlow; Rebecca Chamley; Edward Nicol; David A Holdsworth Detailed characterisation of cardiopulmonary limitations in patients post-COVID-19 is currently limited, particularly...

Incidence of long COVID and associated psychosocial characteristics in a large U.S. city Tsai, Jack; Grace, Abigail; Espinoza, Rita; Kurian, Anita Purpose Persistent residual effects from Coronavirus Disease-2019 (COVID-19) have been observed with varying definitions of “Long COVID” and little...

Long-term health consequences among individuals with SARS-CoV-2 infection compared to individuals without infection: results of the population-based cohort study CoMoLo Follow-up Heidemann, Christin; Sarganas, Giselle; Du, Yong; Gaertner, Beate; Poethko-Müller, Christina; Cohrdes, Caroline...

The study expands on a previously-awarded proposal to thoroughly explore the underlying pathophysiology of post exertional malaise (PEM), the hallmark symptom of ME/CFS. LEAD INVESTIGATORS Laurel Crosby, PhD Ronald W. Davis, PhD...

Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection can lead to postacute sequelae in multiple organ systems, but evidence is mostly limited to the first year postinfection. We built a cohort of 138,818 individuals with SARS-CoV-2 infection and 5,985,227 noninfected...

Abstract Postinfectious syndromes have been described since the Spanish influenza pandemic of 1918. A similar syndrome—post-COVID condition (PCC)—is common; it occurs months after COVID-19 infection and involves fatigue, postexertional malaise, dyspnea, memory loss, diffuse pain, and...

Pathophysiology, diagnosis, and management of neuroinflammation in covid-19 Rachel L Brown; Laura Benjamin; Michael P Lunn; Tehmina Bharucha; Michael S Zandi; Chandrashekar Hoskote; Patricia McNamara; Hadi Manji Although neurological complications of SARS-CoV-2 infection are relatively rare...

Summary Background Case reports suggest that SARS-CoV-2 infection could lead to immune dysregulation and trigger autoimmunity while COVID-19 vaccination is effective against severe COVID-19 outcomes. We aim to examine the association between COVID-19 and development of autoimmune diseases...

Abstract A significant proportion of patients after SARS-CoV-2 infection suffer from long-lasting symptoms. Although many different symptoms are described, the majority of patients complains about neuropsychological symptoms. Additionally, a subgroup of patients fulfills diagnostic criteria for...

The kynurenine pathway relates to post-acute COVID-19 objective cognitive impairment and PASC Abstract Objective To determine the prevalence and natural history of post-acute COVID-19 objective cognitive impairment and function, and their relationship to demographic, clinical factors...

A thread for news from the US that isn't covered by other threads such as (in no particular order) USA: News from the Workwell Foundation. USA: News from Solve ME USA: NIH National Institutes of Health Overview of NIH grants for ME/CFS research USA: News from #MEAction USA: The RECOVER...

Functional characterisation of the ACE2 orthologues in Drosophila provides insights into the neuromuscular complications of COVID-19 Highlights A large percentage of patients with COVID-19 have neuromuscular manifestations. Loss of Drosophila ACE2 orthologues Ance or Ance3 impaired motoric...

Long COVID-19 Cardiac Complications Are Associated With Autoimmunity to Cardiac Self-Antigens Sufficient to Cause Cardiac Dysfunction No access to the paper... https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.122.062672 A post by Eric Topol .

Exercise in long COVID is poorly studied. Nevertheless, exerciserehabilitation could improve cardiorespiratory, muscular and autonomic functions. We aimed to investigate improvement in physical and autonomic performances of long COVID patients (n = 38) after a 4-week exercise rehabilitation...

Long COVID and Significant Activity Limitation Among Adults, by Age — United States, June 1–13, 2022, to June 7–19, 2023 Nicole D. Ford et al. Long COVID is a condition encompassing a wide range of health problems that emerge, persist, or return following COVID-19. CDC analyzed national repeat...

Ivabradine effects on COVID-19-associated postural orthostatic tachycardia syndrome: a single center prospective study Background: A wide range of cardiac arrhythmias were reported in the setting of active infection or as a complication of COVID-19. The main pathophysiology can be attributed...

Core mitochondrial genes are down-regulated during SARS-CoV-2 infection of rodent and human hosts Joseph W. Guarnieri; Joseph M. Dybas; Hossein Fazelinia; Man S. Kim; Justin Frere; Yuanchao Zhang; Yentli Soto Albrecht; Deborah G. Murdock; Alessia Angelin; Larry N. Singh; Scott L. Weiss; Sonja M...

Attenuation of ferroptosis as a potential therapeutic target for neuropsychiatric manifestations of post-COVID syndrome Sousa, Ricardo A. L.; Yehia, Asmaa; Abulseoud, Osama A. Coronavirus disease-19 (COVID-19), caused by severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2), is...

Long COVID in a highly vaccinated population infected during a SARS-CoV-2 Omicron wave - Australia, 2022 Mulu Woldegiorgis; Gemma Cadby; Sera Ngeh; Rosemary Korda; Paul Armstrong; Jelena Maticevic; Paul Knight; Andrew Jardine; Lauren Bloomfield; Paul Effler Objective: To characterise Long COVID...

Forming a consensus opinion to inform long COVID support mechanisms and interventions: a modified Delphi approach Background Current approaches to support patients living with post-COVID condition, also known as Long COVID, are highly disparate with limited success in managing or resolving a...