long covid

Impact of fatigue as the primary determinant of functional limitations among patients with post-COVID-19 syndrome: a cross-sectional observational study Sarah Walker; Henry Goodfellow; Patra Pookarnjanamorakot; Elizabeth Murray; Julia Bindman; Ann Blandford; Katherine Bradbury; Belinda Cooper...

Not sure how the following paragraph even made it in when we're talking about a 31% increase in GP visits for this in 25-44 year olds... Back to reality... Article

Critical COVID-19 disease is accompanied by depletion of plasma tryptophan (TRY) and increases in indoleamine-dioxygenase (IDO)-stimulated production of neuroactive tryptophan catabolites (TRYCATs), including kynurenine (KYN). The TRYCAT pathway has not been studied extensively in association...

Key Points Question Is translocator protein distribution volume (TSPO VT), an index of gliosis (an inflammatory change), measured by positron emission tomography, elevated in the brain after acute COVID-19 infection with sequelae of depressive and cognitive symptoms? Findings In this...

Recovery and symptom trajectories up to two years after SARS-CoV-2 infection: population based, longitudinal cohort study Tala Ballouz; Dominik Menges; Alexia Anagnostopoulos; Anja Domenghino; Hélène E Aschmann; Anja Frei; Jan S Fehr; Milo A Puhan Objective To evaluate longer term symptoms and...

Long-Term Adverse Effects of Mild COVID-19 Disease on Arterial Stiffness, and Systemic and Central Hemodynamics: A Pre-Post Study Podrug, Mario; Koren, Pjero; Dražić Maras, Edita; Podrug, Josip; Čulić, Viktor; Perissiou, Maria; Bruno, Rosa Maria; Mudnić, Ivana; Boban, Mladen; Jerončić, Ana...

Introduction: Many people with long COVID symptoms suffer from debilitating neurologic post-acute sequelae of SARS-CoV-2 infection (Neuro-PASC). Although symptoms of Neuro-PASC are widely documented, it is still unclear whether PASC symptoms impact virus-specific immune responses. Therefore, we...

Detecting Orthostatic Intolerance in Long COVID in a Clinic Setting Isaac, Robert Oliver; Corrado, Joanna; Sivan, Manoj Introduction: A likely mechanism of Long COVID (LC) is dysautonomia, manifesting as orthostatic intolerance (OI). In our LC service, all patients underwent a National...

Abstract Rheumatology, such as other subspecialties, has both a unique perspective to offer as well as an evolving role to play in the global COVID-19 pandemic. Our field has already contributed meaningfully to the development and repurposing of many of the immune-based therapeutics which are...

Development of a Definition of Postacute Sequelae of SARS-CoV-2 Infection IMPORTANCE SARS-CoV-2 infection is associated with persistent, relapsing, or new symptoms or other health effects occurring after acute infection, termed postacute sequelae of SARS-CoV-2 infection (PASC), also known as...

Post-COVID Patients With New-Onset Chronic Pain 2 Years After Infection: Cross-Sectional Study Andrés Calvache-Mateo; Alba Navas-Otero; Alejandro Heredia-Ciuró; Javier Matín-Núñez; Irene Torres-Sánchez; Laura López-López; Marie Carmen Valenza Background: Although pain is common in...

Brain imaging and neuropsychological assessment of individuals recovered from a mild to moderate SARS-CoV-2 infection Petersen, Marvin; Nägele, Felix Leonard; Mayer, Carola; Schell, Maximilian; Petersen, Elina; Kühn, Simone; Gallinat, Jürgen; Fiehler, Jens; Pasternak, Ofer; Matschke, Jakob...

New-onset, self-reported long COVID after coronavirus (COVID-19) reinfection in the UK Download as PDF Main points 4.0% of adults (aged 16 years and over) and 1.0% of children and young people (aged 2 to 15 years) reported having long COVID 12 to 20 weeks after a first coronavirus...

ELUCIDate long-term consequences of Childhood Infections using administrative and research Data https://elucidatestudy.blogs.bristol.ac.uk/about-us/ https://elucidatestudy.blogs.bristol.ac.uk/

Abstract To describe the prevalence of long COVID in children infected for the first time (n=332) or reinfected (n=243) with Omicron variant SARS-CoV-2, compared with test-negative children (n=311). 12-16% infected with Omicron met the research definition of long COVID at 3 and 6 months after...

Abstract: Post-COVID-19 syndrome is an ongoing challenge for healthcare systems as well as for society. The clinical picture of post-COVID-19 syndrome is heterogeneous, including fatigue, sleep disturbances, pain, hair loss, and gastrointestinal symptoms such as chronic diarrhea. Neurological...

Neurologic sequelae of COVID-19 are determined by immunologic imprinting from previous coronaviruses Spatola, Marianna; Nziza, Nadège; Jung, Wonyeong; Deng, Yixiang; Yuan, Dansu; Dinoto, Alessandro; Bozzetti, Silvia; Chiodega, Vanessa; Ferrari, Sergio; Lauffenburger, Douglas A; Mariotto, Sara...

Systematic review of the prevalence of Long Covid Woodrow, Mirembe; Carey, Charles; Ziauddeen, Nida; Thomas, Rebecca; Akrami, Athena; Lutje, Vittoria; Greenwood, Darren C; Alwan, Nisreen A Background: Long Covid occurs in those infected with SARSCoV2 whose symptoms persist or develop beyond the...

eBioMedicine Part of THE LANCET Discovery Science Post COVID-19 condition after delta infection and omicron reinfection in children and adolescents Summary Background The burden of COVID-19 in children and adolescents has increased during the delta and omicron waves, necessitating studies of...

Abstract Background: One of the major challenges currently faced by global health systems is the prolonged COVID-19 syndrome (also known as long COVID) which has emerged as a consequence of the SARS-CoV-2 epidemic. The World Health Organization (WHO) recognized long COVID as a distinct clinical...