microcirculation

Subclinical neurovascular and immune correlates of post-COVID-19 syndrome detected by retinal imaging BACKGROUND Post-COVID-19 Syndrome (PCS) encompasses a range of persistent symptoms, including cognitive and autonomic disturbances, potentially linked to microvascular or neuroinflammatory...

Uncovering the hidden biology of fibrinaloid microclot complexes in complex, inflammatory diseases Grixti, Justine; Pretorius, Etheresia; Kell, Douglas B. Abstract Abstract Blood can clot into anomalous, fibrinolysis-resistant forms that arise from prothrombotic seeding areas, including...

Beneficial Effect of COVID-19 Vaccination on Decreased Pulmonary Vascular and Airway Volumes of Patients with Long-COVID Syndrome BACKGROUND Despite normal lung imaging and preserved pulmonary and cardiac function, many patients with long COVID continue to experience persistent respiratory...

A28-22 Association of Coronary Vasomotor Disorders and Myalgic Encephalomyelitis/ Chronic Fatigue Syndrome in Patients Undergoing Invasive Cardiopulmonary Exercise Testing Introduction Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (MECFS) is characterized by 6 months of reduced ability...

Impaired microvascular reactivity in post-COVID-19 syndrome is independent of cardiorespiratory fitness Current evidence demonstrates that patients that suffer from long-term SARS-CoV-2 symptoms (i.e., post-COVID-19 syndrome, PCS) often present muscle fatigue and dyspnea. This is discussed to...

Microcirculatory impairment and increased arterial stiffness in pediatric Long COVID patients PURPOSE The exact pathogenesis of Long COVID remains unclear. Microvascular and endothelial dysfunction, established contributors to SARS-CoV-2-related conditions, appear to play a role in pediatric...

Interrogating pulmonary diffusing capacity in long COVID: insights from DLCO and DLNO testing INTRODUCTION The lingering respiratory effects of COVID-19, particularly in patients with Long COVID, remain poorly understood, prompting a comprehensive evaluation of lung function in this...

Association of foveal avascular zone FAZ enlargement with SARS-CoV-2 infection and long COVID-19 BACKGROUND As COVID-19 was found to affect small vessels of multiple organ systems, the purpose of the study is to describe the macular vessel density (VD) and the area of the foveal avascular zone...

Endothelial TERT drives microvascular phenotype associated with coronary artery disease Erin C. Birch; Yoshinori Nishijima; Shelby N. Hader; Andreas M. Beyer Microvascular endothelial dysfunction is a powerful predictor of future atherosclerotic cardiac events. Our previous studies revealed...

COVID-19 Patients Have Peripheral Microvascular Dysfunction and Tissue Hypoxia in Spite of Successful Treatment of Lung Failure: A Proof of Concept Study Knut Kvernebo; L. Liv Kristin Wikslund; Kamila Drezek; Andrea Jaramillo; Luigino Capone; Maged Helmy; Yunong Zhao; Aaron Aguirre; David...

Deoxygenation Trends and Their Multivariate Association with Self-Reported Fatigue in Post-COVID Syndrome Anja-Maria Ladek, Marianna Lucio, Andreas Weiß, Thomas Knauer, Helena Sarmiento, Miriam Ilgner, Marie Jakobi, Laura Barteczko, Marion Ganslmayer, Jürgen Rech, Antonio Bergua, Christian Y...

Is COVID-19 Coagulopathy a Thrombotic Microangiopathy? A Prospective, Observational Study Silingardi, Mauro; Zappulo, Fulvia; Dormi, Ada; Pizzini, Attilia Maria; Donadei, Chiara; Cappuccilli, Maria; Fantoni, Chiara; Zaccaroni, Stefania; Pizzuti, Valeria; Cilloni, Nicola; Tantillo, Simona; Guidi...

Ischaemic endothelial necroptosis induces haemolysis and COVID-19 angiopathy Wu, Mike C. L.; Italiano, Ethan; Jarvis-Child, Rocko; Alwis, Imala; Smythe, Rhyll; Albornoz, Eduardo A.; Noonan, Jonathan; Portelli, Marie; Baptista, Marissa; Maclean, Jessica; Noori, Pashtana; Yang, Jinglu; Lee, John...

Long COVID Mechanisms, Microvascular Effects and Evaluation Based on Incidence Aristotle G. Koutsiaris, Kostas Karakousis Abstract Since the initial reports of Long COVID symptoms, numerous pathophysiological mechanisms have been proposed to explain them; nevertheless, no consensus has been...

Multicentre retrospective detection of nailfold videocapillaroscopy abnormalities in long covid patients Lia Ginaldi; Giovanna Cuomo; Study Group on Capillaroscopy and Microcirculation in Rheumatic Diseases of the Italian Society of Rheumatology (Capsir); Emanuele Gotelli; Rosanna Campitiello...

Astrocytic mitochondrial transfer to brain endothelial cells and pericytes in vivo increases with aging Gopal V Velmurugan; Hemendra J Vekaria; Samir P Patel; Patrick G Sullivan; W Brad Hubbard Intercellular mitochondrial transfer (IMT) is an intriguing biological phenomenon where mitochondria...

Follow-up assessment of the microvascular function in patients with long COVID Romanowska-Kocejko; Braczko; Jędrzejewska; Żarczyńska-Buchowiecka; Kocejko; Kutryb-Zając; Hellmann Long COVID is a complex pathophysiological condition. However, accumulating data suggests that COVID-19 is a systemic...

Preprint, see next post for peer-reviewed version. ---------------------------------------------------------------- Assessing Cerebral Microvascular Volumetric Pulsatility with High-Resolution 4D CBV MRI at 7T Fanhua Guo; Chenyang Zhao; Qinyang Shou; Ning Jin; Kay Jann; Xingfeng Shao; Danny JJ...

Thrombotic Consequences of COVID-19 Infection on Microsurgical Reconstruction Sabrina H. Han; Kyle Ockerman; Matthew Kirchmier; Markos Mardourian; Jaimie Bryan; Elizabeth Cox; Harvey Chim; Lisa Spiguel; Arash Momeni; Sarah Sorice-Virk BACKGROUND Evidence has shown increased morbidity and...

Abstract Background: The term “Long COVID” is commonly used to describe persisting symptoms after acute COVID‑19. Until now, proposed mechanisms for the explanation of Long COVID have not related quantitative measurements to basic laws. In this work, a common framework for the Long COVID...