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monocytes
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Monocyte-Mediated Thrombosis Linked to Circulating Tissue Factor and Immune Paralysis in COVID-19, 2024, Goonewardena et al.
Monocyte-Mediated Thrombosis Linked to Circulating Tissue Factor and Immune Paralysis in COVID-19 Sascha N. Goonewardena; Qinzhong Chen; Ashley M. Tate; Olga G. Grushko; Dilna Damodaran; Pennelope K. Blakely; Salim S. Hayek; David J. Pinsky; Robert S. Rosenson BACKGROUND SARS-CoV-2 infections...- SNT Gatchaman
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- coagulation complement immunoparalysis immunothrombosis innate immune system monocytes tissue factor toll-like receptor
- Replies: 1
- Forum: Epidemics (including Covid-19, not Long Covid)
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The longitudinal characterization of immune responses … reveals novel prognostic signatures for disease severity [& LC], 2024, Noviello+
The longitudinal characterization of immune responses in COVID-19 patients reveals novel prognostic signatures for disease severity, patients’ survival and long COVID Noviello, Maddalena; De Lorenzo, Rebecca; Chimienti, Raniero; Maugeri, Norma; De Lalla, Claudia; Siracusano, Gabriel; Lorè...- SNT Gatchaman
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- b cells immune monocytes mortality nk cells nkg2a t cells
- Replies: 0
- Forum: Long Covid research
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The choroid plexus synergizes with immune cells during neuroinflammation, 2024, Xu et al.
The choroid plexus synergizes with immune cells during neuroinflammation Huixin Xu; Peter Lotfy; Sivan Gelb; Aja Pragana; Christine Hehnly; Lillian I.J. Byer; Frederick B. Shipley; Miriam E. Zawadzki; Jin Cui; Liwen Deng; Milo Taylor; Mya Webb; Hart G.W. Lidov; Mark L. Andermann; Isaac M. Chiu...- SNT Gatchaman
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- cerebrospinal fluid choroid plexus immune system innate immune response macrophages monocytes neuroinflammation neutrophils
- Replies: 1
- Forum: Other health news and research
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Bioinformatic analysis predicts the regulatory function of noncoding SNPs associated with Long COVID-19 syndrome, 2024, Maiti, Amit K.
Bioinformatic analysis predicts the regulatory function of noncoding SNPs associated with Long COVID-19 syndrome Maiti, Amit K. Long or Post COVID-19 is a condition of collected symptoms persisted after recovery from COVID-19. Host genetic factors play a crucial role in developing Long...- SNT Gatchaman
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- bioinformatics epigenetics gwas long covid monocytes snp t cells
- Replies: 0
- Forum: Long Covid research
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The life-saving benefit of dexamethasone in severe COVID-19 is linked to a reversal of monocyte dysregulation, 2024, Knoll et al.
The life-saving benefit of dexamethasone in severe COVID-19 is linked to a reversal of monocyte dysregulation Rainer Knoll; Elisa T. Helbig; Kilian Dahm; Olufemi Bolaji; Frederik Hamm; Oliver Dietrich; Martina van Uelft; Sophie Müller; Lorenzo Bonaguro; Jonas Schulte-Schrepping; Lev Petrov...- SNT Gatchaman
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- covid 19 immune dysregulation monocytes steroids
- Replies: 0
- Forum: Epidemics (including Covid-19, not Long Covid)
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Sex differences and immune correlates of Long COVID development, persistence, and resolution, 2024, Hamlin et al.
Sex differences and immune correlates of Long COVID development, persistence, and resolution Rebecca E Hamlin; Shaun M Pienkos; Leslie Chan; Mikayla A Stabile; Kassandra Pinedo; Mallika Rao; Philip Grant; Hector Bonilla; Marisa Holubar; Upinder Singh; Karen B Jacobson; Prasanna Jagannathan...- SNT Gatchaman
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- ets1 integrins interferon interferon-y monocytes nf-κb nk cells sex differences t cells tgf-beta
- Replies: 7
- Forum: Long Covid research
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Review Cellular and Molecular Effects of Microgravity on the Immune System: A Focus on Bioactive Lipids, 2024, Fava et al.
Cellular and Molecular Effects of Microgravity on the Immune System: A Focus on Bioactive Lipids Fava, Marina; De Dominicis, Noemi; Forte, Giulia; Bari, Monica; Leuti, Alessandro; Maccarrone, Mauro Microgravity is one of the main stressors that astronauts are exposed to during space missions...- SNT Gatchaman
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- immune system inflammation innate immune system lipids monocytes
- Replies: 0
- Forum: Other health news and research
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Preprint Antibody-mediated cellular responses are dysregulated in Multisystem Inflammatory Syndrome in Children MIS-C, 2024, Dick et al.
Antibody-mediated cellular responses are dysregulated in Multisystem Inflammatory Syndrome in Children MIS-C Jenna K Dick; Jules A Sangala; Venkatramana D Krishna; Aaron Khaimraj; Lydia Hamel; Spencer M Erickson; Dustin Hicks; Yvette Soigner; Laura E Covill; Alexander Johnson; Michael J...- SNT Gatchaman
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- mis-c monocytes nk cells
- Replies: 1
- Forum: Long Covid research
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Preprint Sex differences in symptomatology and immune profiles of Long COVID, 2024, Silva, Putrino, Iwasaki et al.
Sex differences in symptomatology and immune profiles of Long COVID Julio Silva; Takehiro Takahashi; Jamie Wood; Peiwen Lu; Sasha Tabachnikova; Jeffrey Gehlhausen; Kerrie Greene; Bornali Bhattacharjee; Valter Silva Monteiro; Carolina Lucas; Rahul Dhodapkar; Laura Tabacof; Mario Pena-Hernandez...- SNT Gatchaman
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- april cmv complement cortisol dendritic cells ebv endocrine endocrine regulation hsv2 immune system interferon long covid monocytes nk cells oestrogen sex differences t cells testosterone
- Replies: 2
- Forum: Long Covid research
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Persistence of circulating CD169+monocytes and HLA-DR downregulation underline the immune response impairment in PASC, 2024, Fanelli et al.
Persistence of circulating CD169+monocytes and HLA-DR downregulation underline the immune response impairment in PASC individuals: the potential contribution of different COVID-19 pandemic waves Fanelli; Petrone; Maracchioni; Chirico; Cipriani; Coppola; Malagnino; Teti; Sorace; Zordan; Vitale...- SNT Gatchaman
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- cd169 hla inflammation long covid monocytes myeloid cells
- Replies: 0
- Forum: Long Covid research
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Single-cell RNA-Seq reveals intracellular microbial diversity within immune cells during SARS-CoV-2 infection and recovery, 2023, Sunita Yadav et al
Highlights 76 bacterial species of 15 genera across healthy, COVID-19-positive, and recovered individuals Higher abundance of opportunistic intracellular bacteria in recovered group Higher microbial abundance within antigen-presenting cells of COVID-19 patients Differential microbial abundance...- Mij
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- b cells covid dendritic cells innate immune response intracellular infection intracellular pathogen macrophages monocytes nk cells pbmc plasma cells platelets single-cell transcriptomics t cells
- Replies: 6
- Forum: Epidemics (including Covid-19, not Long Covid)
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Alterations to Sphingomyelin Metabolism Affect Hemostasis and Thrombosis, 2023, Wang et al.
Alterations to Sphingomyelin Metabolism Affect Hemostasis and Thrombosis Jue Wang; Shiva Keshava; Kaushik Das; Richard Kolesnick; Xian-Cheng Jiang; Usha R. Pendurthi; L. Vijaya Mohan Rao BACKGROUND: Our recent studies suggest that sphingomyelin levels in the plasma membrane influence TF (tissue...- SNT Gatchaman
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- coagulation endothelium lipid rafts lipids macrophages monocytes platelets sphingolipids sphingomyelin tissue factor
- Replies: 2
- Forum: Other health news and research
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Helicobacter pylori induces a novel form of innate immune memory via accumulation of NF-кB proteins, 2023, Frauenlob et al.
Helicobacter pylori induces a novel form of innate immune memory via accumulation of NF-кB proteins Frauenlob, Tobias; Neuper, Theresa; Regl, Christof; Schaepertoens, Veronika; Unger, Michael S.; Oswald, Anna-Lena; Dang, Hieu-Hoa; Huber, Christian G.; Aberger, Fritz; Wessler, Silja...- SNT Gatchaman
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- helicobacter pylori innate immune response innate immune system monocytes nf-κb
- Replies: 3
- Forum: Other health news and research
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[Preprint] NK cell-monocyte crosstalk underlies NK cell activation in severe COVID-19, 2023, Lee et al.
NK cell-monocyte crosstalk underlies NK cell activation in severe COVID-19 Madeline J Lee; Izumi de los Rios Kobara; Trisha R Barnard; Xariana Vales Torres; Nicole H Tobin; Kathie G Ferbas; Anne W J Rimoin; Otto O Yang; Grace M Aldrovandi; Aaron James Wilk; Jennifer Fulcher; Catherine A Blish...- SNT Gatchaman
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- cd69 chemokines covid monocytes nk cells nkg2d tgf-beta
- Replies: 1
- Forum: Epidemics (including Covid-19, not Long Covid)
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Preprint A 50-gene high-risk profile predictive of COVID & pulmonary fibrosis mortality from molecular imbalance in monocyte & T-cell subsets, 2023, Tourki +
A 50-gene high-risk profile predictive of COVID-19 and Idiopathic Pulmonary Fibrosis mortality originates from a molecular imbalance in monocyte and T-cell subsets that reverses in survivors with post-COVID-19 Interstitial Lung Disease Bochra Tourki; Minxue Jia; Theodoros Karampitsakos; Iset M...- SNT Gatchaman
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- cd163 fibrosis gene expression hspc il-6 ild ipf lung fibrosis lungs monocytes pbmc sars-cov-2 tgf-beta
- Replies: 2
- Forum: Long Covid research
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A myeloid program associated with COVID-19 severity is decreased by therapeutic blockade of IL-6 signaling, 2023, Hackney et al.
A myeloid program associated with COVID-19 severity is decreased by therapeutic blockade of IL-6 signaling Altered myeloid inflammation and lymphopenia are hallmarks of severe infections. We identified the upregulated EN-RAGE gene program in airway and blood myeloid cells from patients with...- SNT Gatchaman
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- en-rage il-6 monocytes myeloid cells t cells
- Replies: 3
- Forum: Epidemics (including Covid-19, not Long Covid)
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Immunological profiling in long COVID: overall low grade inflammation and T-lymphocyte senescence and increased monocyte activation..., Hellemonds+
Immunological profiling in long COVID: overall low grade inflammation and T-lymphocyte senescence and increased monocyte activation correlating with increasing fatigue severity Background: Many patients with SARS-CoV-2 infection develop long COVID with fatigue as one of the most disabling...- EndME
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- ccl2 ccl7 immunology long covid monocytes t-cells
- Replies: 2
- Forum: Long Covid research
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Vaccination after developing long COVID: impact on clinical presentation, viral persistence and immune responses, 2023, Nayyerabadi et al.
Vaccination after developing long COVID: impact on clinical presentation, viral persistence and immune responses Maryam Nayyerabadi; Lyvia Fourcade; Swarali A. Joshi; Prabha Chandrasekaran; Arpita Chakravarti; Chantal Massé; Marie-Lorna Paul; Joanie Houle; Amina M. Boubekeur; Charlotte DuSablon...- SNT Gatchaman
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- cytokines inflammation long covid monocytes spike protein vaccination
- Replies: 5
- Forum: Long Covid research
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SARS-CoV-2 infection induces a long-lived pro-inflammatory transcriptional profile, 2023, Zhang et al.
SARS-CoV-2 infection induces a long-lived pro-inflammatory transcriptional profile Zhang, Jia-Yuan; Whalley, Justin P.; Knight, Julian C.; Wicker, Linda S.; Todd, John A.; Ferreira, Ricardo C. The immune response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in...- SNT Gatchaman
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- autoimmunity b-cells ecm extracellular matrix il-2 inflammation long covid monocytes nf-κb nk cells sars-cov-2 t-cells tnf
- Replies: 1
- Forum: Long Covid research
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Epigenetic memory of coronavirus infection in innate immune cells and their progenitors, 2023, Cheong et al.
Epigenetic memory of coronavirus infection in innate immune cells and their progenitors Jin-Gyu Cheong; Arjun Ravishankar; Siddhartha Sharma; Christopher N. Parkhurst; Simon A. Grassmann; Claire K. Wingert; Paoline Laurent; Sai Ma; Lucinda Paddock; Isabella C. Miranda; Emin Onur Karakaslar...- SNT Gatchaman
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- bone marrow covid-19 epigenetics haematopoietic stem cell progenitors hspc il-6 immune dysfunction innate immune system monocytes stem cells trained innate immunity
- Replies: 6
- Forum: Long Covid research