multiple sclerosis

https://www.forbes.com/sites/robinseatonjefferson/2018/04/27/report-offers-hope-outlines-537-new-drugs-in-development-for-neurological-disorders/

https://www.everydayhealth.com/multiple-sclerosis/treatment/new-guidelines-ms-treatment-start-treatment-early/

This is a few years old, but really highlights the similarities between these two illnesses (and thus makes the difference in treatments more stark). Does anybody with any understanding of the specifics here have any comments? What do we think: is ME like MS? Certainly, the early literature...

http://www.bbc.co.uk/news/resources/idt-sh/caroline_wyatt_multiple_sclerosis ME and Rituximab get a very brief mention each. An interesting account of HSCT ("Stem Cell Reboot").

From what I can see, there's a lot of conjecture here, more than anything else. It's looking at the role of hormones in autoimmune diseases, and whether testosterone is protective. There are a few links to small/emerging studies. Info here...

Two threads on the same topic and created at the same time have been merged

ME Association Press Release: People with M.E. ‘measurably more disabled’ than people with Multiple Sclerosis | 16 March 2018 http://www.meassociation.org.uk/2018/03/me-association-press-release-people-with-m-e-measurably-more-disabled-than-people-with-multiple-sclerosis-16-march-2018/

Caroline C. Kingdon, Erinna W. Bowman, Hayley Curran, Luis Nacul, Eliana M. Lacerda https://link.springer.com/article/10.1007%2Fs41669-018-0071-6

The author has ME. " 6 February 2018 — 11:00pm As recently as 1921, MS (multiple sclerosis) was erroneously considered more common in men. By the late 1940s, a more even gender split was presumed. By 1960 it was posited that women might actually be slightly more prone to the condition. With the...

Lacking the resources to write more -- just would like to let you know how the German Patient Organisation for MS "AMSEL" handles the issue of false (psycho-) perceptions of illness related fatigue. Apologies for the Google translation (always funny though) - hope the key message is not lost...

Paywalled at https://www.sciencedirect.com/science/article/pii/S0022399917304361

From Jun 2017 Full text at https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5477754/

foxp3 is relevant for MS could other fox genes be relevant for me/cfs I never see this mentioned and think it might be worth a look https://multiplesclerosisnewstoday.com/2017/07/07/foxp3-gene-mutations-may-cause-aggressive-immune-system-responses-in-multiple-sclerosis-other-diseases/...

For those interested in these things this is a useful review (and hypothesis) of possible mechanisms for 'central fatigue' in MS and other neurological disorders (full paper). Not directly relevant to ME/CFS although several ME/CFS studies are referenced. Possibly the most interesting (and...

This article was from a few months ago, but I just saw it. It's about multiple sclerosis, but perhaps something useful can be gleaned from it. Original article: http://www.nejm.org/doi/10.1056/NEJMoa1608889 Is anyone aware of any minocycline studies for ME/CFS?

Published back in August but I didn't notice it then. Small pilot study. http://onlinelibrary.wiley.com/wol1/doi/10.1111/cpf.12460/abstract

https://www.theguardian.com/society/2017/nov/03/radical-new-approach-to-schizophrenia-treatment-begins-trial

Just thought this was interesting. http://neurosciencenews.com/multiple-sclerosis-computer-simulation-7828/ Full open access at http://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1005757

e I don't think this has much interest for ME because they are talking about repairing Myelin. But I think it is a good example of drug re purposing. https://www.ucsf.edu/news/2017/10/408646/allergy-drug-improves-function-patients-chronic-injury-multiple-sclerosis