multiple sclerosis

  1. wastwater

    T cell-selective deletion of Oct1 protects animals from autoimmune neuroinflammation while maintaining neurotropic pathogen response (2019) Tantin

    https://multiplesclerosisnewstoday.com/news-posts/2019/07/03/study-in-mice-suggests-possible-treatment-approach-for-multiple-sclerosis-in-humans/
  2. Woolie

    Multiple sclerosis-associated fatigue. Krupp et al. (2010)

    Not a new article, but I was struck by this comment on the relation between fatigue and pro-inflammatory cytokines: link to the article here There are are no consistently observed associations between fatigue in ME and levels of pro-inflammatory cytokines. But its interesting to see we're not...
  3. J

    The effect of evening primrose oil on fatigue and quality of life in patients with multiple sclerosis

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6003444/ Fig. 5 looks pretty good. Anybody try this?
  4. A

    MS - ancient viral DNA and inflammatory immune response

    Interesting bit if research via Twitter tonight. Relevant to ME ? https://www.pasteur.fr/en/research-journal/news/discovery-mechanism-responsible-chronic-inflammation-patients-suffering-multiple-sclerosis?hootPostID=81f61df8a3de6b440bfd9a65a34a12ef
  5. C

    MS society question people on the streets to ask what they know about MS

    I thought that this was interesting and would be interesting to do with ME so we target our education efforts better. I was wondering whether it Can be incorporated into #MISSINGMILLIONS when our people are on the streets , perhaps giving out an information leaflet alongside? Tbh I suspect few...
  6. leokitten

    Living Proof: documentary about MS and corruption in pharmaceutical industry and national MS society

    I enjoyed watching this documentary recently, absolutely heartbreaking Living Proof (2017) https://www.imdb.com/title/tt6604174/ If ME ever gets to the stage where MS is in terms of awareness, research funding, pharmaceutical industry involvement and treatments, this story shows how patient...
  7. MSEsperanza

    Fatigue measurement scales

    Elbers, R.G., Rietberg, M.B., van Wegen, E.E.H. et al. (2012), Self-report fatigue questionnaires in multiple sclerosis, Parkinson’s disease and stroke: a systematic review of measurement properties, Qual Life Res (2012) 21: 925. https://doi.org/10.1007/s11136-011-0009-2 Abstract: Chalder...
  8. J

    Feasibility RCT of cocoa for fatigue in MS (2019) Coe et al

    Drink cocoa for chronic fatigue. Not a recommendation. Not looked at details. https://jnnp.bmj.com/content/early/2019/01/31/jnnp-2018-319496
  9. NelliePledge

    Current Research Project: Understanding the neural mechanisms of fatigue & memory impairments in CFS/ME & Multiple Sclerosis using fMRI

    I tried looking to see if there’s already a thread for this couldn’t find one but my search skills are a bit ropey please delete if there is one http://www.bristol.ac.uk/cricbristol/research/fatigue-research/ Crawley and others at Bristol doing fMRIs on CFS and MS folks
  10. Alvin

    Researchers Find A Web Of Factors Behind Multiple Sclerosis

    https://www.npr.org/sections/health-shots/2019/01/21/684495345/researchers-find-a-web-of-factors-behind-multiple-sclerosis
  11. Andy

    Hope, disappointment and perseverance: Reflections of people with ME/CFS and MS participating in biomedical research..., 2019, Lacerda et al

    Open access at https://onlinelibrary.wiley.com/doi/full/10.1111/hex.12857
    • Andy
    • Thread
    • 2019 diagnosis lacerda lshtm me/cfs multiple sclerosis paper patient experience qualitative treatment
    • Replies: 2
    • Forum: ME/CFS research
  12. Webdog

    Recirculating Intestinal IgA-Producing Cells Regulate Neuroinflammation via IL-10, 2019, Rojas et al

    Study: Recirculating Intestinal IgA-Producing Cells Regulate Neuroinflammation via IL-10 https://doi.org/10.1016/j.cell.2018.11.035 Press Release: Gut Immune Cells Cut Inflammation in Multiple Sclerosis https://www.ucsf.edu/news/2018/12/412941/gut-immune-cells-cut-inflammation-multiple-sclerosis
  13. Sly Saint

    ‘It’s the unknown’ – understanding anxiety: from the perspective of people with multiple sclerosis (2018) Chalder et al

    Moderator note This thread has been split off from this thread about fatigue in MS and ME. ‘It’s the unknown’ – understanding anxiety: from the perspective of people with multiple sclerosis Chalder Objective: A qualitative study of PwMS who had clinically significant levels of anxiety was...
  14. M

    Food allergies are associated with increased disease activity in multiple sclerosis

    Food allergies are associated with increased disease activity in multiple sclerosis https://jnnp.bmj.com/content/early/2018/12/14/jnnp-2018-319301 Abstract Objective The association between allergy and multiple sclerosis (MS) is still unclear. In our study, we assessed the association between...
  15. Webdog

    Possible Biomarker for Multiple Sclerosis Identified

    Possible Biomarker for Multiple Sclerosis Identified https://neurosciencenews.com/multiple-sclerosis-biomarker-10380/
  16. Dolphin

    Epstein-Barr virus–specific T cell therapy for progressive multiple sclerosis

    Somebody with ME was excited by this on Twitter https://insight.jci.org/articles/view/124714 Research ArticleClinical trialsNeuroscience Free access | 10.1172/jci.insight.124714 Epstein-Barr virus–specific T cell therapy for progressive multiple sclerosis Michael P. Pender,1,2,3 Peter A...
  17. Esther12

    Adolescent and parent factors related to fatigue in paediatric multiple sclerosis and CFS: A comparative study (2019) Carroll, Chalder, Moss-Morris

    The abstract made it sound like another study that tries to confuse association and causation where their data didn't really support their narrative, but I stopped reading before getting to their results... too many infuriating unfounded claims to read before bed in just the intro. Funded by MS...
  18. Sly Saint

    NICE to update guidelines for MS - Oct 2018

    2018 surveillance of multiple sclerosis in adults: management (NICE guideline CG186) "Recommendation 1.5.5 recommends that mindfulness‑based training, cognitive behavioural therapy or fatigue management are considered for treating MS‑related fatigue. New evidence indicates that these...
  19. Andy

    Antigenic mimicry of ubiquitin by the gut bacterium Bacteroides fragilis: a potential link with autoimmune disease, 2018, Patrick et al

    Open access at https://onlinelibrary.wiley.com/doi/full/10.1111/cei.13195 Article based on this paper https://www.infectioncontroltoday.com/immune-system/researchers-discover-new-link-between-autoimmune-diseases-and-gut-bacterium
    • Andy
    • Thread
    • autoimmune disease bacteroides fragilis coeliac microbiome multiple sclerosis rheumatoid arthritis ubiquitin ulcerative colitis
    • Replies: 1
    • Forum: Other health news and research
  20. Webdog

    GDP-l-fucose synthase is a CD4+ T cell–specific autoantigen in DRB3*02:02 patients with multiple sclerosis (2018) Planas et al

    Study: GDP-l-fucose synthase is a CD4+ T cell–specific autoantigen in DRB3*02:02 patients with multiple sclerosis http://stm.sciencemag.org/content/10/462/eaat4301 Press Release: Link between gut flora and multiple sclerosis discovered https://www.sciencedaily.com/releases/2018/10/181011103636.htm
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