nk cells

  1. John Mac

    Investigation into the restoration of TRPM3 ion channel activity in post COVID-19 ...,Sasso, Marshall-Gradisnik et al,2024

    Full title: Investigation into the restoration of TRPM3 ion channel activity in post COVID-19 condition: a potential pharmacotherapeutic target Recently, we reported that post COVID-19 condition patients also have Transient Receptor Potential Melastatin 3 (TRPM3) ion channel dysfunction, a...
    • John Mac
    • Thread
    • covid 19 griffith university ion channel marshall-gradisnik mc/cfs naltrexone hydrochloride natural killer cells nk cells ntx trpm3
    • Replies: 5
    • Forum: Long Covid research
  2. SNT Gatchaman

    Preprint Sex differences in symptomatology and immune profiles of Long COVID, 2024, Silva, Putrino, Iwasaki et al.

    Sex differences in symptomatology and immune profiles of Long COVID Julio Silva; Takehiro Takahashi; Jamie Wood; Peiwen Lu; Sasha Tabachnikova; Jeffrey Gehlhausen; Kerrie Greene; Bornali Bhattacharjee; Valter Silva Monteiro; Carolina Lucas; Rahul Dhodapkar; Laura Tabacof; Mario Pena-Hernandez...
    • SNT Gatchaman
    • Thread
    • april cmv complement cortisol dendritic cells ebv endocrine endocrine regulation hsv2 immune system interferon long covid monocytes nk cells oestrogen sex differences t cells testosterone
    • Replies: 2
    • Forum: Long Covid research
  3. SNT Gatchaman

    Review Defining trained immunity and its role in health and disease, 2020, Netea et al.

    Defining trained immunity and its role in health and disease Netea, Mihai G.; Domínguez-Andrés, Jorge; Barreiro, Luis B.; Chavakis, Triantafyllos; Divangahi, Maziar; Fuchs, Elaine; Joosten, Leo A. B.; van der Meer, Jos W. M.; Mhlanga, Musa M.; Mulder, Willem J. M.; Riksen, Niels P.; Schlitzer...
  4. Mij

    Single-cell RNA-Seq reveals intracellular microbial diversity within immune cells during SARS-CoV-2 infection and recovery, 2023, Sunita Yadav et al

    Highlights 76 bacterial species of 15 genera across healthy, COVID-19-positive, and recovered individuals Higher abundance of opportunistic intracellular bacteria in recovered group Higher microbial abundance within antigen-presenting cells of COVID-19 patients Differential microbial abundance...
    • Mij
    • Thread
    • b cells covid dendritic cells innate immune response intracellular infection intracellular pathogen macrophages monocytes nk cells pbmc plasma cells platelets single-cell transcriptomics t cells
    • Replies: 6
    • Forum: Epidemics (including Covid-19, not Long Covid)
  5. SNT Gatchaman

    Sex-dependent differences in type I IFN-induced natural killer cell activation, 2023, Pujantell et al.

    Sex-dependent differences in type I IFN-induced natural killer cell activation Pujantell, Maria; Skenteris, Nikolaos-Taxiarchis; Claussen, Janna Marieke; Grünhagel, Benjamin; Thiele, Rebecca-Jo; Altfeld, Marcus Natural killer (NK) cells are important antiviral effector cells and also involved...
  6. Midnattsol

    Hypothesis Ineffective control of Epstein-Barr-virus-induced autoimmunity increases the risk for multiple sclerosis, 2023, Vietzen et al.

    I wasn't sure what prefix to use given that the paper has been accepted in Cell but not published. I read about it in a paywalled news article as the abstract was presented at the ECTRIMS 2023. Ineffective Immune Control of Epstein-Barr Virus-Induced Autoreactive Responses is an Important Cause...
  7. E

    SARS-CoV-2 viral persistence in lung alveolar macrophages is controlled by IFN-γ and NK cells, 2023, Huot et al

    SARS-CoV-2 viral persistence in lung alveolar macrophages is controlled by IFN-γ and NK cells Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA generally becomes undetectable in upper airways after a few days or weeks postinfection. Here we used a model of viral...
    • EndME
    • Thread
    • animal study fibronectin interferon interferon-y lungs macrophages nk cells t cells viral persistence
    • Replies: 4
    • Forum: Long Covid research
  8. SNT Gatchaman

    Single-cell profiling identifies distinct hormonal, immunologic, and inflammatory signatures of endometriosis-constituting cells, 2023, Shin et al.

    Single-cell profiling identifies distinct hormonal, immunologic, and inflammatory signatures of endometriosis-constituting cells Sun Shin; Youn-Jee Chung; Seong Won Moon; Eun Ji Choi; Mee-Ran Kim; Yeun-Jun Chung; Sug Hyung Lee Endometriosis consists of ectopic endometrial epithelial cells...
  9. SNT Gatchaman

    [Preprint] NK cell-monocyte crosstalk underlies NK cell activation in severe COVID-19, 2023, Lee et al.

    NK cell-monocyte crosstalk underlies NK cell activation in severe COVID-19 Madeline J Lee; Izumi de los Rios Kobara; Trisha R Barnard; Xariana Vales Torres; Nicole H Tobin; Kathie G Ferbas; Anne W J Rimoin; Otto O Yang; Grace M Aldrovandi; Aaron James Wilk; Jennifer Fulcher; Catherine A Blish...
  10. SNT Gatchaman

    SARS-CoV-2 infection induces a long-lived pro-inflammatory transcriptional profile, 2023, Zhang et al.

    SARS-CoV-2 infection induces a long-lived pro-inflammatory transcriptional profile Zhang, Jia-Yuan; Whalley, Justin P.; Knight, Julian C.; Wicker, Linda S.; Todd, John A.; Ferreira, Ricardo C. The immune response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in...
    • SNT Gatchaman
    • Thread
    • autoimmunity b-cells ecm extracellular matrix il-2 inflammation long covid monocytes nf-κb nk cells sars-cov-2 t-cells tnf
    • Replies: 1
    • Forum: Long Covid research
  11. Sly Saint

    Review Surveying the Metabolic and Dysfunctional Profiles of T Cells and NK Cells in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome 2023, Maya

    Abstract: Millions globally suffer from myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). The inflammatory symptoms, illness onset, recorded outbreak events, and physiological variations provide strong indications that ME/CFS, at least sometimes, has an infectious origin, possibly...
  12. SNT Gatchaman

    Tissue Determinants of Human NK Cell Development, Function, and Residence, 2020, Dogra et al.

    Tissue Determinants of Human NK Cell Development, Function, and Residence Pranay Dogra; Chiara Rancan; Wenji Ma; Marta Toth; Takashi Senda; Dustin J. Carpenter; Masaru Kubota; Rei Matsumoto; Puspa Thapa; Peter A. Szabo; Maya Meimei Li Poon; Jacky Li; Janice Arakawa-Hoyt; Yufeng Shen; Lawrence...
  13. Sly Saint

    Altered TRPM7-Dependent Calcium Influx in Natural Killer Cells of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Patients, 2023, du Preez et al

    Abstract: Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a disabling multisystemic condition. The pathomechanism of ME/CFS remains unestablished; however, impaired natural killer (NK) cell cytotoxicity is a consistent feature of this condition. Calcium (Ca2+) is crucial for NK...
    • Sly Saint
    • Thread
    • calcium calcium channels channelopathy griffith university marshall-gradisnik nk cells trpm trpm7
    • Replies: 4
    • Forum: ME/CFS research
  14. SNT Gatchaman

    Plasma proteome of Long-COVID patients indicates HIF-mediated vasculo-proliferative disease with impact on brain and heart function, 2023, Iosef et al

    Plasma proteome of Long-COVID patients indicates HIF-mediated vasculo-proliferative disease with impact on brain and heart function Iosef, Cristiana; Knauer, Michael J.; Nicholson, Michael; Van Nynatten, Logan R.; Cepinskas, Gediminas; Draghici, Sorin; Han, Victor K. M.; Fraser, Douglas D. Aims...
    • SNT Gatchaman
    • Thread
    • ang-1 hif-1 long covid neutrophil extracellular traps neutrophils nf-κb nk cells tnf vascular vegf
    • Replies: 3
    • Forum: Long Covid research
  15. Sly Saint

    Detection of ADCC-Supporting Antibodies by NK-92-CD16A Cell Externalization of CD107a: Recognition of Antibody Afucosylation and Assay Optimization

    Abstract Antibody-dependent cell-mediated cytotoxicity (ADCC) by natural killer (NK) lymphocytes eliminates cells infected with viruses. Antiviral ADCC requires three components: 1) antibody; 2) effector lymphocytes with the Fc-IgG receptor CD16A; and 3) viral proteins in infected cell...
  16. SNT Gatchaman

    [Preprint] Mild/Asymptomatic Maternal Covid Infection Leads to Immune Paralysis in Fetal Circulation and Immune Dysregulation in Fetus-Placenta

    Mild/Asymptomatic Maternal SARS-CoV-2 Infection Leads to Immune Paralysis in Fetal Circulation and Immune Dysregulation in Fetal-Placental Tissues Brianna M Doratt; Suhas Sureshchandra; Heather True; Monica Rincon; Nicole E Marshall; Ilhem Messaoudi Few studies have addressed the impact of...
  17. SNT Gatchaman

    Immune profiling of SARS-CoV-2 infection during pregnancy reveals NK cell and γδ T cell perturbations, 2023, Habel et al.

    Immune profiling of SARS-CoV-2 infection during pregnancy reveals NK cell and γδ T cell perturbations Jennifer R. Habel; Brendon Y. Chua; Lukasz Kedzierski; Kevin J. Selva; Timon Damelang; Ebene R. Haycroft; Thi H.O. Nguyen; Hui-Fern Koay; Suellen Nicholson; Hayley A. McQuilten; Xiaoxiao Jia...
  18. Andy

    A patient-centric modeling framework captures recovery from SARS-CoV-2 infection, 2023, Ruffieux et al

    Abstract The biology driving individual patient responses to severe acute respiratory syndrome coronavirus 2 infection remains ill understood. Here, we developed a patient-centric framework leveraging detailed longitudinal phenotyping data and covering a year after disease onset, from 215...
    • Andy
    • Thread
    • innate immune system kynurenine lipidomics long covid metabolomics nicholson nk cells
    • Replies: 7
    • Forum: Long Covid research
  19. B

    Altered Fatty Acid Oxidation in Lymphocyte Populations of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, 2023, Maya et al

    https://www.mdpi.com/1422-0067/24/3/2010 Abstract Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a disabling multisystem illness in which individuals are plagued with fatigue, inflammatory symptoms, cognitive dysfunction, and the hallmark symptom, post-exertional malaise. While...
    • Braganca
    • Thread
    • fatty acid metabolism maureen hanson metabolism natural killer cells nk cells seahorse t cells t-cells
    • Replies: 15
    • Forum: ME/CFS research
  20. SNT Gatchaman

    SARS-CoV-2 escapes direct NK cell killing through Nsp1-mediated downregulation of ligands for NKG2D, 2022, Lee et al

    SARS-CoV-2 escapes direct NK cell killing through Nsp1-mediated downregulation of ligands for NKG2D Madeline J. Lee, Michelle W. Leong, Arjun Rustagi, Aimee Beck, Leiping Zeng, Susan Holmes,4 Lei S. Qi, Catherine A. Blish Natural killer (NK) cells are cytotoxic effector cells that target and...
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