The psychological and physiological effects of a virtual reality-based treatment program in female patients with fibromyalgia syndrome: A randomized controlled trial. Sari et al, 2025
Abstract
The study aims to evaluate the effects of virtual reality (VR) programs on disease activity, central...
Abstract
Debilitating symptoms of fatigue and accompanying “brain fog” are observed among patients with various chronic health conditions. Unfortunately, an efficient and psychometrically sound instrument to assess these co-occurring symptoms is unavailable. Here, we report the development and...
Study Overview
Brief Summary
Psychological distress (anxiety and depression) is common in and experienced differently by people living with long-term health conditions (LTCs). Being able to measure whether psychological distress is related to living with a LTC would allow researchers and...
Now published - link here
Preprint
Pediatric and Adult Patients with ME/CFS following COVID-19: A Structured Approach to Diagnosis Using the Munich Berlin Symptom Questionnaire MBSQ
Laura C. Peo; Katharina Wiehler; Johannes Paulick; Katrin Gerrer; Ariane Leone; Anja Viereck; Matthias Haegele...
Many questionnaires used to measure depression ask about general symptoms such as fatigue, sleep, appetite, concentration etc. People with a chronic illness such as ME/CFS already have those symptoms and are thus more likely to score high on these depression questionnaires, even if they are not...
Detecting Orthostatic Intolerance in Long COVID in a Clinic Setting
Isaac, Robert Oliver; Corrado, Joanna; Sivan, Manoj
Introduction:
A likely mechanism of Long COVID (LC) is dysautonomia, manifesting as orthostatic intolerance (OI). In our LC service, all patients underwent a National...
BACKGROUND:
Existing instruments often are inappropriate to measure the effects of post-exertional malaise (PEM) and post-exertional symptom exacerbation (PESE) on activities of daily living (ADLs). A validated questionnaire to measure self-reported ability with ADLs would advance research and...
NEO-FFI (Five factor inventory, Borkenau and Ostendorf1993; Costa and McCrae1992).
The following study assessed the stability of the Big Five personalty traits, by asking people to watch a 10 minute emotion-inducing film, and then think of happy or sad times while listening to an appropriate...
We have other threads where we take a serious look at some questionnaires and their misleading results when used in ME/CFS research. The classic case of this is the Chalder Fatigue Questionnaire, yet we still see it used even by otherwise respected ME/CFS clinicians/researchers.
I participated...
[Anxiety in patients with postural tachycardia syndrome (POTS)]
Article in German
C Wagner, S Isenmann, H Ringendahl, C-A Haensch
Background: The postural tachycardia syndrome (POTS) is a condition of the autonomic nervous system with symptoms of orthostatic intolerance. In POTS patients...
Abstract
Objective To describe the development and validation of a novel patient reported outcome measure for symptom burden from long covid, the symptom burden questionnaire for long covid (SBQ-LC).
Design Multiphase, prospective mixed methods study.
Setting Remote data collection and social...
Posts have been copied from this thread about a study that used the MFI.
The intro to the linked MFI questionnaire says
Does anyone know what validation study they refer to? Because, applied to ME, some of the MFI questions are extremely open to different interpretations. Not to mention...
Now published. https://www.s4me.info/threads/assessing-functional-capacity-in-me-cfs-a-patient-informed-questionnaire-funcap-2024-sommerfelt-et-al.35464/page-3#post-538060
The discussion thread before the preprint was published and the preprint thread have been merged.
Discussion of the...
I am raising this topic for discussion because I think there are fundamental problems with the design and use of questionnaires in ME/CFS and other medical research.
Questions for consideration:
1. Should questionnaires ever be used to draw conclusions about psychological factors affecting...
Abstract
Central Sensitization (CS) has been proposed as a common pathophysiological mechanism to explain related syndromes for which no specific organic cause can be found. The term Central Sensitivity Syndrome (CSS) has been proposed to describe these poorly understood disorders related to...
https://link.springer.com/article/10.1186/s12991-020-00311-5
Primary research
Open Access
Published: 09 October 2020
Norwegian reference data on the Fatigue Questionnaire and the Patient Health Questionnaire-9 and their interrelationship
Alv A. Dahl1,2* , Kjersti Støen Grotmol3, Marianne...
I thought that this was of some interest as it has Wessely seeming to be unusually open about the limitations of questionnaires for assessing symptoms/disorders. Though this time that's seemingly partly because it goes against the 'work is good for you' creed used by the UK government (Waddell &...
I am a bit skeptical about this.
https://publichealth.berkeley.edu/news-media/research-highlights/new-screening-tool-may-predict-chronic-pain-before-it-starts/
This seems to be an important article, hits many points and arguments that have been made repeatedly on this forum, namely that there is a problem with the content validity of questionnaires that measure catastrophizing.
Here the Belgian authors looked at the validity of six pain...
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