spike protein

  1. SNT Gatchaman

    Vaccination after developing long COVID: impact on clinical presentation, viral persistence and immune responses, 2023, Nayyerabadi et al.

    Vaccination after developing long COVID: impact on clinical presentation, viral persistence and immune responses Maryam Nayyerabadi; Lyvia Fourcade; Swarali A. Joshi; Prabha Chandrasekaran; Arpita Chakravarti; Chantal Massé; Marie-Lorna Paul; Joanie Houle; Amina M. Boubekeur; Charlotte DuSablon...
  2. SNT Gatchaman

    [Preprint] Identification of a Druggable Site on GRP78 at the GRP78-SARS-CoV-2 Interface and Compounds to Disrupt that Interface, 2023, Lazou et al.

    Identification of a Druggable Site on GRP78 at the GRP78-SARS-CoV-2 Interface and Compounds to Disrupt that Interface Maria Lazou; Jonathan R. Hutton; Arijit Chakravarty; Diane Joseph-McCarthy SARS-CoV-2, the virus that causes COVID-19, led to a global health emergency that claimed the lives of...
  3. SNT Gatchaman

    SARS-CoV-2 spike protein induces endothelial inflammation via ACE2 independently of viral replication, 2023, Montezano et al.

    SARS-CoV-2 spike protein induces endothelial inflammation via ACE2 independently of viral replication Montezano, Augusto C.; Camargo, Livia L.; Mary, Sheon; Neves, Karla B; Rios, Francisco J; Stein, Ross; Lopes, Rheure A.; Beattie, Wendy; Thomson, Jacqueline; Herder, Vanessa; Szemiel, Agnieszka...
  4. SNT Gatchaman

    Are the integrin binding motifs within SARS CoV-2 spike protein and MHC class II alleles playing the key role in COVID-19?, 2023, Gerencer & McGuffin

    Are the integrin binding motifs within SARS CoV-2 spike protein and MHC class II alleles playing the key role in COVID-19? Gerencer, Marijan; McGuffin, Liam J. The previous studies on the RGD motif (aa403-405) within the SARS CoV-2 spike (S) protein receptor binding domain (RBD) suggest that...
  5. SNT Gatchaman

    SARS-CoV-2 spike protein receptor-binding domain perturbates intracellular Ca homeostasis & impairs pulmonary vascular endothelial cells, 2023, Yang+

    SARS-CoV-2 spike protein receptor-binding domain perturbates intracellular calcium homeostasis and impairs pulmonary vascular endothelial cells Yang, Kai; Liu, Shiyun; Yan, Han; Lu, Wenju; Shan, Xiaoqian; Chen, Haixia; Bao, Changlei; Feng, Huazhuo; Liao, Jing; Liang, Shuxin; Xu, Lei; Tang...
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    • calcium channels covid endothelial endothelial cells lungs microvascular sars-cov-2 spike protein vascular
    • Replies: 3
    • Forum: Long Covid research
  6. SNT Gatchaman

    SARS-CoV-2 spike protein induces lung endothelial cell dysfunction and thrombo-inflammation depending on the C3a/C3a receptor signalling, 2023 Perico+

    SARS-CoV-2 spike protein induces lung endothelial cell dysfunction and thrombo-inflammation depending on the C3a/C3a receptor signalling Perico, Luca; Morigi, Marina; Pezzotta, Anna; Locatelli, Monica; Imberti, Barbara; Corna, Daniela; Cerullo, Domenico; Benigni, Ariela; Remuzzi, Giuseppe The...
  7. SNT Gatchaman

    SARS-COV-2 spike protein fragment eases amyloidogenesis of α-synuclein, 2023, Chesney et al.

    SARS-COV-2 spike protein fragment eases amyloidogenesis of α-synuclein Chesney, Andrew D.; Maiti, Buddhadev; Hansmann, Ulrich H. E. Parkinson’s Disease is accompanied by presence of amyloids in the brain formed of α-synuclein chains. Correlation between COVID-19 and the onset of Parkinson’s...
  8. SNT Gatchaman

    Cellular microRNAs target SARS-CoV-2 spike protein and restrict viral replication, 2023, Vaddadi et al.

    Cellular microRNAs target SARS-CoV-2 spike protein and restrict viral replication Kishore Vaddadi ; Chaitanya Gandikota ; Chaoqun Huang ; Yurong Liang ; Lin Liu MicroRNAs (miRNAs) regulate gene expression post-transcriptionally and are implicated in viral replication and host tropism...
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    High-Density Lipoprotein function is modulated by the SARS-CoV-2 spike protein in a lipid-type dependent manner, 2023, Correa et al.

    High-Density Lipoprotein function is modulated by the SARS-CoV-2 spike protein in a lipid-type dependent manner Correa; Del Giudice; Waldie; Thépaut; Micciula; Gerelli; Moulin; Delaunay; Fieschi; Pichler; Haertlein; Forsyth; Le Brun; Moir; Russell; Darwish; Brinck; Wodaje; Jansen; Martín...
  10. SNT Gatchaman

    Molecular Analysis of SARS-CoV-2 Spike Protein-Induced Endothelial Cell Permeability and vWF Secretion, 2023, Guo et al.

    Molecular Analysis of SARS-CoV-2 Spike Protein-Induced Endothelial Cell Permeability and vWF Secretion Guo, Yuexi; Kanamarlapudi, Venkateswarlu Coronavirus disease COVID-19, which is caused by severe acute respiratory syndrome coronavirus SARS-CoV-2, has become a worldwide pandemic in recent...
  11. SNT Gatchaman

    Spike Protein Impairs Mitochondrial Function in Human Cardiomyocytes: Mechanisms Underlying Cardiac Injury in COVID-19, 2023, Huynh et al.

    Spike Protein Impairs Mitochondrial Function in Human Cardiomyocytes: Mechanisms Underlying Cardiac Injury in COVID-19 Huynh, Tin Van; Rethi, Lekha; Lee, Ting-Wei; Higa, Satoshi; Kao, Yu-Hsun; Chen, Yi-Jen Background: COVID-19 has a major impact on cardiovascular diseases and may lead to...
  12. SNT Gatchaman

    Circulating Spike Protein Detected in Post–COVID-19 mRNA Vaccine Myocarditis, 2023, Yonker et al.

    Circulating Spike Protein Detected in Post–COVID-19 mRNA Vaccine Myocarditis Lael M. Yonker; Zoe Swank; Yannic C. Bartsch; Madeleine D. Burns; Abigail Kane; Brittany P. Boribong; Jameson P. Davis; Maggie Loiselle; Tanya Novak; Yasmeen Senussi; Chi-An Cheng; Eleanor Burgess; Andrea G. Edlow...
  13. SNT Gatchaman

    SARS-CoV-2 Spike Protein Accumulation in the Skull-Meninges-Brain Axis: Potential Implications for Long-Term Neurological Complications

    SARS-CoV-2 Spike Protein Accumulation in the Skull-Meninges-Brain Axis: Potential Implications for Long-Term Neurological Complications in post-COVID-19 Zhouyi Rong; Hongcheng Mai; Saketh Kapoor; Victor Puelles; Jan Czogalla; Julia Schaedler; Jessica Vering; Claire Delbridge; Hanno Steinke...
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    • bone marrow brain coagulation complement long covid meninges neurological disorder neurological symptoms sars-cov-2 skull spike protein viral persistence
    • Replies: 14
    • Forum: Long Covid research
  14. SNT Gatchaman

    [Preprint] Murine Alveolar Macrophages Rapidly Accumulate Intranasally Administered Spike Protein leading to Neutrophil Recruitment & Damage, NIH

    Murine Alveolar Macrophages Rapidly Accumulate Intranasally Administered SARS-CoV-2 Spike Protein leading to Neutrophil Recruitment and Damage Chung Park, Il-Young Hwang, Serena Li-Sue Yan, Sinmanus Vimonpatranon, Danlan Wei, Don Van Ryk, Claudia Cicala, James Arthos, John H Kehrl (National...
  15. SNT Gatchaman

    Determination of IgG1 and IgG3 SARS-CoV-2 Spike Protein and Nucleocapsid Binding-Who Is Binding Who and Why?, 2022, Iles et al

    Determination of IgG1 and IgG3 SARS-CoV-2 Spike Protein and Nucleocapsid Binding-Who Is Binding Who and Why? Iles JK, Zmuidinaite R, Sadee C, Gardiner A, Lacey J, Harding S, Wallis G, Patel R, Roblett D, Heeney J, Baxendale H, Iles RK The involvement of immunoglobulin (Ig) G3 in the humoral...
  16. SNT Gatchaman

    SARS-CoV-2 Spike Protein Binding of Glycated Serum Albumin-Its Potential Role in the Pathogenesis of the COVID-19 Clinical Syndromes, 2022, Iles et al

    SARS-CoV-2 Spike Protein Binding of Glycated Serum Albumin-Its Potential Role in the Pathogenesis of the COVID-19 Clinical Syndromes and Bias towards Individuals with Pre-Diabetes/Type 2 Diabetes and Metabolic Diseases Iles J, Zmuidinaite R, Sadee C, Gardiner A, Lacey J, Harding S, Ule J...
  17. SNT Gatchaman

    Severe COVID-19 induces autoantibodies against angiotensin II that correlate with blood pressure dysregulation and disease severity, 2022, Briquez &

    Severe COVID-19 induces autoantibodies against angiotensin II that correlate with blood pressure dysregulation and disease severity Briquez PS, Rouhani SJ, Yu J, Pyzer AR, Trujillo J, Dugan HL, Stamper CT, Changrob S, Sperling AI, Wilson PC, Gajewski TF, Hubbell JA, Swartz MA Patients infected...
  18. SNT Gatchaman

    A Case Report: Multifocal Necrotizing Encephalitis and Myocarditis after BNT162b2 mRNA Vaccination against COVID-19, Mörz, 2022

    A Case Report: Multifocal Necrotizing Encephalitis and Myocarditis after BNT162b2 mRNA Vaccination against COVID-19 Michael Mörz The current report presents the case of a 76-year-old man with Parkinson’s disease (PD) who died three weeks after receiving his third COVID-19 vaccination. The...
  19. SNT Gatchaman

    SARS-CoV-2 Spike protein promotes vWF secretion and thrombosis via endothelial cytoskeleton-associated protein 4 (CKAP4), 2022, Li et al

    SARS-CoV-2 Spike protein promotes vWF secretion and thrombosis via endothelial cytoskeleton-associated protein 4 (CKAP4) Kan Li, Liu Yao, Jin Wang, Hao Song, Yan-hong Zhang, Xue Bai, Kai Zhang, Dong-ming Zhou, Ding Ai, Yi Zhu Letter to Nature: Signal Transduction and Targeted Therapy Link | PDF
  20. SNT Gatchaman

    [Preprint] Liquid biomarkers of macrophage dysregulation & circulating spike protein illustrate the biological heterogeneity in patients with LC, 2022

    Liquid biomarkers of macrophage dysregulation and circulating spike protein illustrate the biological heterogeneity in patients with post-acute sequelae of COVID-19 Christoph Schultheiss, Edith Willscher, Lisa Paschold, Cornelia Gottschick, Bianca Klee, Lidia Bosurgi, Jochen Dutzmann, Daniel...
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