t cells

  1. SNT Gatchaman

    Preprint Persistent Activation of Chronic Inflammatory Pathways in Long Covid, 2024, Aid et al.

    Persistent Activation of Chronic Inflammatory Pathways in Long Covid Malika Aid; Katherine McMahan; Nicole Hachmann; Jessica Miller; Erica Borducchi; David Hope; Marjorie Rowe; Eleanor Schonberg; Siline Thai; Ai-ris Collier; Janet Mullington; Dan Barouch Long Covid, or Post-Acute Sequelae of...
  2. SNT Gatchaman

    Oxidative Stress is a shared characteristic of ME/CFS and Long COVID, 2024, Shankar, Bonilla, Davis et al.

    Oxidative Stress is a shared characteristic of ME/CFS and Long COVID Vishnu Shankar; Julie Wilhelmy; Basil Michael; Layla Cervantes; Vamsee Mallajosyula; Ronald Davis; Michael Snyder; Shady Younis; William H Robinson; Sadasivan Shankar; Paul Mischel; Hector Bonilla; Mark Davis More than 65...
  3. J

    T cells in health and disease Sun et al 2023

    https://www.nature.com/articles/s41392-023-01471-y Very long article Abstract T cells are crucial for immune functions to maintain health and prevent disease. T cell development occurs in a stepwise process in the thymus and mainly generates CD4+ and CD8+ T cell subsets. Upon antigen...
  4. John Mac

    Improvement of immune dysregulation in individuals with long COVID at 24-months following SARS-CoV-2 infection, Matthews et al, 2024

    n=31 Improvement of immune dysregulation in individuals with long COVID at 24-months following SARS-CoV-2 infection Abstract This study investigates the humoral and cellular immune responses and health-related quality of life measures in individuals with mild to moderate long COVID (LC)...
  5. SNT Gatchaman

    Review Systems analysis of innate and adaptive immunity in Long COVID, 2024, Peluso et al.

    Systems analysis of innate and adaptive immunity in Long COVID Peluso; Abdel-Mohsen; Henrich; Roan Since the onset of the COVID-19 pandemic, significant progress has been made in developing effective preventive and therapeutic strategies against severe acute SARS-CoV-2 infection. However, the...
  6. SNT Gatchaman

    Preprint Sex differences in symptomatology and immune profiles of Long COVID, 2024, Silva, Putrino, Iwasaki et al.

    Sex differences in symptomatology and immune profiles of Long COVID Julio Silva; Takehiro Takahashi; Jamie Wood; Peiwen Lu; Sasha Tabachnikova; Jeffrey Gehlhausen; Kerrie Greene; Bornali Bhattacharjee; Valter Silva Monteiro; Carolina Lucas; Rahul Dhodapkar; Laura Tabacof; Mario Pena-Hernandez...
  7. SNT Gatchaman

    Blood–brain barrier disruption and sustained systemic inflammation in individuals with long COVID-associated cognitive impairment, 2024, Greene et al

    Preprint Blood-brain barrier disruption in Long COVID-associated cognitive impairment Chris Greene, Ruairi Connolly, Declan Brennan, Aoife Laffan, Eoin O'Keeffe, Lilia Zaporojan, Emma Connolly, Cliona Ni Cheallaigh, Niall Conlon, Colin Doherty, Matthew Campbell Vascular disruption has been...
  8. SNT Gatchaman

    Preprint Restrained memory CD8+ T cell responses favors viral persistence and elevated IgG responses in patients with severe Long COVID., 2024, Rodriguez et al

    Restrained memory CD8+ T cell responses favors viral persistence and elevated IgG responses in patients with severe Long COVID. Lucie Rodriguez; Ziyang Tan; Lakshmi Kanth Tadepally; Jun Wang; Hugo Barcenilla; Zoe Swank; Fanglei Zuo; Hassan Abolhassani; Ana Jimena Pavlovitch-Bedzyk; Chunlin Wang...
  9. SNT Gatchaman

    Preprint Genome-wide association study reveals different T cell distributions in blood of individuals at high genetic risk of type 1 diabetes & LC,2024,Deecke+

    Genome-wide association study reveals different T cell distributions in peripheral blood of healthy individuals at high genetic risk of type 1 diabetes and long COVID Laura Deecke; Jan Homann; David Goldeck; Felix Luessi; Marijne Vandebergh; Olena Ohlei; Sarah Toepfer; Frauke Zipp; Ilja Demuth...
  10. Mij

    Expression profiling of cerebrospinal fluid identifies dysregulated antiviral mechanisms in multiple sclerosis, Maria Ban et al

    Abstract Despite the overwhelming evidence that multiple sclerosis is an autoimmune disease, relatively little is known about the precise nature of the immune dysregulation underlying the development of the disease. Reasoning that the CSF from patients might be enriched for cells relevant in...
  11. SNT Gatchaman

    Persistent CD8+ T cell proliferation and activation in [PASC]: a longitudinal, observational cohort study, 2024, LaVergne et al.

    Persistent CD8+ T cell proliferation and activation in COVID-19 adult survivors with post-acute sequelae: a longitudinal, observational cohort study of persistent symptoms and T cell markers LaVergne, Stephanie M.; Dutt, Taru S.; McFann, Kim; Webb, Tracy L.; Henao-Tamayo, Marcela; Ryan...
  12. E

    Targeted depletion of TRBV9+ T cells as immunotherapy in a patient with ankylosing spondylitis, 2023, Chudakov et al

    Targeted depletion of TRBV9+ T cells as immunotherapy in a patient with ankylosing spondylitis Abstract Autoimmunity is intrinsically driven by memory T and B cell clones inappropriately targeted at self-antigens. Selective depletion or suppression of self-reactive T cells remains a holy grail...
  13. E

    Expanded T lymphocytes in the cerebrospinal fluid of multiple sclerosis patients are specific for Epstein-Barr-virus-infected B cells, 2024, Gottlieb+

    Expanded T lymphocytes in the cerebrospinal fluid of multiple sclerosis patients are specific for Epstein-Barr-virus-infected B cells Significance On average, 13% of the T lymphocytes in the cerebrospinal fluid of people with the first symptoms of multiple sclerosis are specific for autologous...
  14. Mij

    Single-cell RNA-Seq reveals intracellular microbial diversity within immune cells during SARS-CoV-2 infection and recovery, 2023, Sunita Yadav et al

    Highlights 76 bacterial species of 15 genera across healthy, COVID-19-positive, and recovered individuals Higher abundance of opportunistic intracellular bacteria in recovered group Higher microbial abundance within antigen-presenting cells of COVID-19 patients Differential microbial abundance...
  15. Midnattsol

    Hypothesis Ineffective control of Epstein-Barr-virus-induced autoimmunity increases the risk for multiple sclerosis, 2023, Vietzen et al.

    I wasn't sure what prefix to use given that the paper has been accepted in Cell but not published. I read about it in a paywalled news article as the abstract was presented at the ECTRIMS 2023. Ineffective Immune Control of Epstein-Barr Virus-Induced Autoreactive Responses is an Important Cause...
  16. E

    Chikungunya-virus-specific CD4+ T cells are associated with chronic chikungunya viral arthritic disease in humans, 2023, Chang et al

    Chikungunya-virus-specific CD4+ T cells are associated with chronic chikungunya viral arthritic disease in humans Abstract Chikungunya virus (CHIKV) is a mosquito-borne re-emerging viral infection that can cause chronic chikungunya viral arthritic disease (CHIKVD), which is characterized by...
  17. SNT Gatchaman

    [Preprint] ... Multi-omics study identifies immune programs associated with COVID-19 severity and mortality in hospitalized participants, 2023

    Integrated longitudinal multi-omics study identifies immune programs associated with COVID-19 severity and mortality in 1152 hospitalized participants Jeremy P. Gygi; Cole Maguire; Ravi K. Patel; Pramod Shinde; Anna Konstorum; Casey P. Shannon; Leqi Xu; Annmarie Hoch; Naresh Jayavelu; IMPACC...
  18. E

    SARS-CoV-2 viral persistence in lung alveolar macrophages is controlled by IFN-γ and NK cells, 2023, Huot et al

    SARS-CoV-2 viral persistence in lung alveolar macrophages is controlled by IFN-γ and NK cells Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA generally becomes undetectable in upper airways after a few days or weeks postinfection. Here we used a model of viral...
  19. SNT Gatchaman

    Sequential multi-omics analysis identifies clinical phenotypes and predictive biomarkers for long COVID, 2023, Wang et al

    Sequential multi-omics analysis identifies clinical phenotypes and predictive biomarkers for long COVID Kaiming Wang; Mobin Khoramjoo; Karthik Srinivasan; Paul M.K. Gordon; Rupasri Mandal; Dana Jackson; Wendy Sligl; Maria B. Grant; Josef M. Penninger; Christoph H. Borchers; David S. Wishart...
  20. SNT Gatchaman

    A myeloid program associated with COVID-19 severity is decreased by therapeutic blockade of IL-6 signaling, 2023, Hackney et al.

    A myeloid program associated with COVID-19 severity is decreased by therapeutic blockade of IL-6 signaling Altered myeloid inflammation and lymphopenia are hallmarks of severe infections. We identified the upregulated EN-RAGE gene program in airway and blood myeloid cells from patients with...
Back
Top Bottom