https://www.medrxiv.org/content/10.1101/2021.07.14.21259081v1
Background Coronavirus disease 2019 (COVID-19) is a serious respiratory disease that results from infection with a newly discovered coronavirus (SARS-COV-2). Unfortunately, COVID-19 is not only a short-term infection but that...
This is a press release from a small Swiss pharmaceutical company. I'm sharing it because the newly appointed chief scientific officer said:
"Our lead product candidate, Quilience®, is an exciting technology that we discovered has partial orexin-2 binding activity, and therefore, offers...
The effect of IL-2 stimulation and treatment of TRPM3 on channel co-localisation with PIP2 and NK cell function in myalgic encephalomyelitis/chronic fatigue syndrome patients
Natalie Eaton-Fitch,
Hélène Cabanas,
Stanley du Preez,
Donald Staines &
Sonya Marshall-Gradisnik
Abstract...
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a disease with unknown etiology, no validated specific and sensitive biomarker, and no standard approved effective treatment. ME/CFS has a profound impact on the quality of life of both patients and caregivers and entails high costs...
Full title: Potential therapeutic benefit of Low Dose Naltrexone in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Role of Transient Receptor Potential Melastatin 3 ion channels in pathophysiology and treatment
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a debilitating...
Highlights
• Self-help treatments for young people with persistent physical symptoms are needed.
• The evidence on their effect on symptom burden is still scarce.
• Psychosocial outcomes are only included in few existing studies.
• Hypnotherapy as self-help format shows potential.
• Future...
Objective: Several studies suggested that Qigong exercise (QE) can relieve fatigue in patients diagnosed with various diseases. Our review aimed to evaluate the efficacy of QE for alleviating fatigue.
Methods: A related literature search was performed in the PubMed, Web of Science, Embase...
Authors: Emma C. Anderson, Maria Loades, Jennifer Starbuck, Phil Parker, Fiona Finch, Rebecca Barnes, Lucy Beasant & Esther Crawley
ABSTRACT
Rationale
UK specialist medical care (SMC) for paediatric Chronic Fatigue Syndrome (CFS/ME) includes behavioural approaches (Graded Exercise Therapy...
This is long.
If any one reads it, and have any information about some of the questions i have in there, especially if anyone have information about any other lawsuits against him (non PR related that is), i'd be interested in hearing from you.
I still get the occasional panick attack when...
Abstract
Introduction: Non-pharmacological approaches are recommended as first-line treatment for patients with fibromyalgia. This randomised controlled trial investigated the effects of a multicomponent rehabilitation programme for patients with recently diagnosed fibromyalgia in primary and...
"Approximately 1 in 10 people with COVID-19 continue to experience symptoms and impaired quality of life beyond 12 weeks, which is known as ‘Long COVID’. Common Long COVID symptoms include, extreme tiredness, shortness of breath, chest pain or tightness, ‘brain fog’, insomnia, heart...
First Clinical Study of the Safety and Blood Levels of a Human Monoclonal Antibody (2217LS) Against Lyme Disease Bacteria in Healthy People, 2021, MassBiologics, Phase I
Study Type : Interventional (Clinical Trial)
Estimated Enrollment : 48 participants
Allocation: Randomized
Intervention...
Abstract
Background and Objectives: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a chronic condition distinguished by disabling fatigue associated with post-exertional malaise, as well as changes to sleep, autonomic functioning, and cognition.
Mind-body interventions (MBIs)...
Has anyone had any experience with either of these 2 epilepsy drugs? There are some persistent anecdotal reports that these are helpful for MECFS symptoms.
This old survey showed that patients perceived that topiramate was one of the most effective drugs that people had taken...
(Very unsure where to put this, not quite guidelines, related to ME, but not research either)
(Also unsure why it took 2 years to publish this but it's new)
Part 1 of 2 (according to this tweet).
https://www.sciencedirect.com/science/article/pii/S1566070221000588
Abstract
Postural...
"Introduction
Safe and effective rehabilitation is a fundamental part of recovery from illness and can improve function in people living with disability. Currently insufficient evidence exists to guide best practice for safe and effective rehabilitation in people living with Long COVID...
(Note that this is an old study from 2004)
Abstract
Context: There is no established pharmacological treatment for the core symptoms of chronic fatigue syndrome (CFS). Galantamine hydrobromide, an acetyl cholesterone inhibitor, has pharmacological properties that might benefit patients with...
Abstract
The coronavirus disease (COVID-19), caused by severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) infection, is leading to unknown and unusual health conditions that are challenging to manage. Post-COVID-19 syndrome is one of those challenges, having become increasingly common...
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