treatment

  1. Lidia Thompson

    Antivirals as ME/CFS or Long Covid treatments (e.g. valacyclovir, valgancyclovir, amantadine)

    Split from Mail Online: Why many of those struck by Long Covid may be suffering from glandular fever: Blood tests on some patients are coming back positive for ‘ Here is a link from ME-pedia on the use use of valaciclovir. The study that is mentioned on this page showed that, " Improvement...
  2. Nixxy

    Sodium dichloroacetate

    Hello. I’m not sure what the right category was, but I wanted to share my experience with Prof Comhaire’s sodium dichloroacetate treatment. I’ve been sick since I was 16. I had an (really bad) EBV infection. A year or 5-7 after that, a hospital specializing in CFS/Fibro checked me out and...
  3. John Mac

    Reduced endothelial function in ME/CFS - results from open-label cyclophosphamide intervention study Fluge & Mella 2021

    Full title: Reduced endothelial function in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome - results from open-label cyclophosphamide intervention study Provisionally accepted https://www.frontiersin.org/articles/10.3389/fmed.2021.642710/abstract
  4. Sid

    Lancet Psychiatry: Regulatory requirements for psychological interventions (Purgato, 2021)

    Pretty ironic seeing one of Lancet’s subjournals publishing an editorial calling out the unregulated nature of psychological interventions. https://doi.org/10.1016/S2215-0366(20)30414-4
  5. U

    Ken Ware - Neurophysics therapy

    Does anyone here know Ken Ware? Apparently he’s pretty well known for his rehabilitation work with severe spinal cord injury patients. 5 me/cfs patients (moderate/severe with pots) from the Netherlands have gone to Australia to be treated by this guy and four out five have made an amazing...
  6. A

    Babesia, babesiosis (tick-borne disease)

    New tick found in north east Scotland From Twitter - new trick in Scotland, never found in sheep.previously babesia venatorum https://www.northern-scot.co.uk/news/global-scientific-first-as-parasite-found-in-north-east-sheep-186588/ @duncan @chrisb
  7. Ryan31337

    Randomized Trial of Ivabradine in Patients With Hyperadrenergic [POTS], 2021, Taub et al

    Paywall, https://www.jacc.org/doi/full/10.1016/j.jacc.2020.12.029 Now free access (Oct 2025)
  8. John Mac

    A systematic review of nutraceutical interventions for mitochondrial dysfunctions in ME/CFS, 2021, Marshall-Gradisnik et al

    https://translational-medicine.biomedcentral.com/articles/10.1186/s12967-021-02742-4
  9. John Mac

    Insights from Invasive Cardiopulmonary Exercise Testing of Patients with ME/CFS, 2021, Joseph et al

    https://journal.chestnet.org/article/S0012-3692(21)00256-7/fulltext EDIT: also available here: https://www.sciencedirect.com/science/article/abs/pii/S0012369221002567
  10. leokitten

    Selective translocator protein (TSPO) agonists

    Given that there is anecdotal evidence of lorazepam (Ativan) causing rapid temporary improvement of ME symptoms, even in very severe cases, I’ve wondered why ME researchers aren’t looking more closely at researching selective translocator protein (TSPO) agonists. TSPO is also known as the...
  11. Hutan

    Methylphenidate (Ritalin)

    Does Methylphenidate Reduce the Symptoms of Chronic Fatigue Syndrome?, 2006, Blockmans et al There's this 2006 Belgium study.
  12. Andy

    Low-Dose Dextromethorphan for the Treatment of Fibromyalgia Pain: [..] Longitudinal ... Pilot Trial, 2021, Mueller, Ness, Younger

    Full title: Low-Dose Dextromethorphan for the Treatment of Fibromyalgia Pain: Results from a Longitudinal, Single-Blind, Placebo-Controlled Pilot Trial Open access, https://www.dovepress.com/low-dose-dextromethorphan-for-the-treatment-of-fibromyalgia-pain-resul-peer-reviewed-fulltext-article-JPR
  13. Andy

    Open‐label study with the monoamine stabilizer (‐)‐OSU6162 in myalgic encephalomyelitis/chronic fatigue syndrome, Haghighi et al, 2021

    Open access, https://onlinelibrary.wiley.com/doi/full/10.1002/brb3.2040
  14. John Mac

    Review article: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS): Where Will the Drugs Come From? 2021, Toogood et al

    https://www.sciencedirect.com/science/article/pii/S1043661821000487
  15. Andy

    Journal of Clinical Medicine: Special Issue "Chronic Fatigue Syndrome/Myalgic Encephalomyelitis: Diagnosis and Treatment", 2021

    While I anticipate we will have separate threads for all papers published in this issue, I thought I would highlight the accuracy, or otherwise, of the detail associated with the 'special issue'. Most bolding mine. From https://www.mdpi.com/journal/jcm/special_issues/Chronic_Fatigue A special...
  16. Kitty

    Occupational therapy and ME/CFS

    In my experience of NHS treatment, OTs are the only healthcare professionals who understand how to deal with fatigue. They also know that people's natural response to post-viral illness is not to become fearful of activity, but quite the opposite – they always try to do too much too soon. I've...
  17. Dolphin

    Clinical practice guidelines by the IDSA ... 2020 guidelines for the prevention, diagnosis, and treatment of Lyme disease, 2020, Lantos et al

    https://n.neurology.org/content/neurology/early/2020/11/30/WNL.0000000000011151.full.pdf
  18. Andy

    Lessons Learned from a Rhode Island Academic Out-Patient Lyme and Tick-Borne Disease Clinic, 2020, McCarthy et al

    Abstract on PubMed, https://pubmed.ncbi.nlm.nih.gov/33261237/ Open access, http://rimed.org/rimedicaljournal/2020/12/2020-12-51-contribution-mccarthy.pdf
  19. Dolphin

    Amantadine and L-carnitine treatment of Chronic Fatigue Syndrome, 1997, Plioplys et al

    Copied from this thread https://pubmed.ncbi.nlm.nih.gov/9018019/ Amantadine and L-carnitine treatment of Chronic Fatigue Syndrome A V Plioplys 1, S Plioplys Neurobiology 1997;35(1):16-23. doi: 10.1159/000119325. PMID: 9018019 DOI: 10.1159/000119325 Abstract Carnitine is essential for...
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