treatment

  1. John Mac

    Reduced endothelial function in ME/CFS - results from open-label cyclophosphamide intervention study Fluge & Mella 2021

    Full title: Reduced endothelial function in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome - results from open-label cyclophosphamide intervention study Provisionally accepted https://www.frontiersin.org/articles/10.3389/fmed.2021.642710/abstract
    • John Mac
    • Thread
    • 2021 cyclophosphamide drugs endothelial endothelial function fluge me/cfs mella paper treatment
    • Replies: 20
    • Forum: ME/CFS research
  2. Sid

    Lancet Psychiatry: Regulatory requirements for psychological interventions (Purgato, 2021)

    Pretty ironic seeing one of Lancet’s subjournals publishing an editorial calling out the unregulated nature of psychological interventions. https://doi.org/10.1016/S2215-0366(20)30414-4
  3. 5vforest

    Efficacy of Double-Dose Dapsone Combination Therapy in the Treatment of Chronic Lyme Disease/Post-Treatment Lyme Disease Syndrome (2020, Horowitz)

    Open access, full text: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7690415/
  4. A

    Babesia, babesiosis (tick-borne disease)

    New tick found in north east Scotland From Twitter - new trick in Scotland, never found in sheep.previously babesia venatorum https://www.northern-scot.co.uk/news/global-scientific-first-as-parasite-found-in-north-east-sheep-186588/ @duncan @chrisb
  5. Ryan31337

    Randomized Trial of Ivabradine in Patients With Hyperadrenergic [POTS], 2021, Taub et al

    Paywall, https://www.jacc.org/doi/full/10.1016/j.jacc.2020.12.029 Now free access (Oct 2025)
  6. John Mac

    A systematic review of nutraceutical interventions for mitochondrial dysfunctions in ME/CFS, 2021, Marshall-Gradisnik et al

    https://translational-medicine.biomedcentral.com/articles/10.1186/s12967-021-02742-4
    • John Mac
    • Thread
    • 2021 marshall-gradisnik mitochondria mitochondrial dysfunction nutraceutical review staines treatment
    • Replies: 3
    • Forum: ME/CFS research news
  7. John Mac

    Insights from Invasive Cardiopulmonary Exercise Testing of Patients with ME/CFS, 2021, Joseph et al

    https://journal.chestnet.org/article/S0012-3692(21)00256-7/fulltext EDIT: also available here: https://www.sciencedirect.com/science/article/abs/pii/S0012369221002567
    • John Mac
    • Thread
    • 2021 cpet exercise exercise physiology icpet joseph me/cfs paper pots preload failure treatment
    • Replies: 23
    • Forum: ME/CFS research
  8. leokitten

    Selective translocator protein (TSPO) agonists

    Given that there is anecdotal evidence of lorazepam (Ativan) causing rapid temporary improvement of ME symptoms, even in very severe cases, I’ve wondered why ME researchers aren’t looking more closely at researching selective translocator protein (TSPO) agonists. TSPO is also known as the...
    • leokitten
    • Thread
    • pbr peripheral benzodiazepine receptor translocator protein treatment tspo
    • Replies: 6
    • Forum: Other treatments
  9. Hutan

    Methylphenidate (Ritalin)

    Does Methylphenidate Reduce the Symptoms of Chronic Fatigue Syndrome?, 2006, Blockmans et al There's this 2006 Belgium study.
  10. Andy

    Low-Dose Dextromethorphan for the Treatment of Fibromyalgia Pain: [..] Longitudinal ... Pilot Trial, 2021, Mueller, Ness, Younger

    Full title: Low-Dose Dextromethorphan for the Treatment of Fibromyalgia Pain: Results from a Longitudinal, Single-Blind, Placebo-Controlled Pilot Trial Open access, https://www.dovepress.com/low-dose-dextromethorphan-for-the-treatment-of-fibromyalgia-pain-resul-peer-reviewed-fulltext-article-JPR
  11. Andy

    Open‐label study with the monoamine stabilizer (‐)‐OSU6162 in myalgic encephalomyelitis/chronic fatigue syndrome, Haghighi et al, 2021

    Open access, https://onlinelibrary.wiley.com/doi/full/10.1002/brb3.2040
    • Andy
    • Thread
    • 2021 me/cfs osu6162 paper treatment
    • Replies: 2
    • Forum: ME/CFS research
  12. John Mac

    Review article: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS): Where Will the Drugs Come From? 2021, Toogood et al

    https://www.sciencedirect.com/science/article/pii/S1043661821000487
    • John Mac
    • Thread
    • 2021 covid-19 drugs me/cfs paper seid toogood treatment
    • Replies: 16
    • Forum: ME/CFS research
  13. Andy

    Journal of Clinical Medicine: Special Issue "Chronic Fatigue Syndrome/Myalgic Encephalomyelitis: Diagnosis and Treatment", 2021

    While I anticipate we will have separate threads for all papers published in this issue, I thought I would highlight the accuracy, or otherwise, of the detail associated with the 'special issue'. Most bolding mine. From https://www.mdpi.com/journal/jcm/special_issues/Chronic_Fatigue A special...
    • Andy
    • Thread
    • 2021 diagnosis journal of clinical medicine me/cfs special issue treatment
    • Replies: 12
    • Forum: General ME/CFS news
  14. Kitty

    Occupational therapy and ME/CFS

    In my experience of NHS treatment, OTs are the only healthcare professionals who understand how to deal with fatigue. They also know that people's natural response to post-viral illness is not to become fearful of activity, but quite the opposite – they always try to do too much too soon. I've...
  15. Dolphin

    Clinical practice guidelines by the IDSA ... 2020 guidelines for the prevention, diagnosis, and treatment of Lyme disease, 2020, Lantos et al

    https://n.neurology.org/content/neurology/early/2020/11/30/WNL.0000000000011151.full.pdf
  16. Andy

    Lessons Learned from a Rhode Island Academic Out-Patient Lyme and Tick-Borne Disease Clinic, 2020, McCarthy et al

    Abstract on PubMed, https://pubmed.ncbi.nlm.nih.gov/33261237/ Open access, http://rimed.org/rimedicaljournal/2020/12/2020-12-51-contribution-mccarthy.pdf
  17. Dolphin

    Amantadine and L-carnitine treatment of Chronic Fatigue Syndrome, 1997, Plioplys et al

    Copied from this thread https://pubmed.ncbi.nlm.nih.gov/9018019/ Amantadine and L-carnitine treatment of Chronic Fatigue Syndrome A V Plioplys 1, S Plioplys Neurobiology 1997;35(1):16-23. doi: 10.1159/000119325. PMID: 9018019 DOI: 10.1159/000119325 Abstract Carnitine is essential for...
  18. M

    Review of the Emerging Evidence Demonstrating the Efficacy of Ivermectin in the Prophylaxis and Treatment of COVID-19

    Today, I found this preprint on the efficacy of Ivermectin in COVID-19 prophylaxis and treatment. In the context of COVID-19, Ivermectin looks more promising than any other drug I've read results on. The meta-review is partially based on unpublished data, though; it will take time until all the...
  19. J

    Safety and efficacy of amantadine, modafinil, and methylphenidate for fatigue in multiple sclerosis..., 2020, Nourbakhsh et al

    Safety and efficacy of amantadine, modafinil, and methylphenidate for fatigue in multiple sclerosis: a randomised, placebo-controlled, crossover, double-blind trial https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(20)30354-9/fulltext
  20. Andy

    Effectiveness of Active Therapy-Based Training to Improve the Balance in Patients with Fibromyalgia: A Systematic Review, 2020, Del-Moral-Garcia et al

    Open access, https://www.mdpi.com/2077-0383/9/11/3771/htm
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